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- W2140355294 abstract "Monoiodobromosulfophthalein- I (MIBSP- I), one of the useful radiopharmaceuticals for liver function studies, has been prepared by a simple isotope exchange between the MIBSP and the molecular iodine- I in phosphate buffer, pH 5.3. The pooled cold MIBSP was prepared by a normal iodination of BSP using iodine monochloride, and separated from the iodination mixture by applying a Sephadex LH-20 chromatography. At 10, the exchange rate was so fast that the reaction could be terminated in 5 min to show upto 95% yield. The final product could be obtained simply by further heating for about 5 min in a boiling water bath in the presence of a small amount of hydrogen peroxide, and subsequent pH adjustment and membrane filtration." @default.
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- W2140355294 date "1977-03-01" @default.
- W2140355294 modified "2023-09-24" @default.
- W2140355294 title "A Simple Preparation of Monoiodobromosulfophthalein- 131 I by Isotope Exchange for Medical Use" @default.
- W2140355294 hasPublicationYear "1977" @default.
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