FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140397269> ?p ?o ?g. }

• W2140397269 endingPage "4197" @default.
• W2140397269 startingPage "4189" @default.
• W2140397269 abstract "The targeting of isthmotectal axons in the Xenopus binocular pathway is guided by both activity-dependent cues and activity-independent cues. Abnormal visual activity induced by unilateral eye rotation overrides activity-independent cues and causes isthmotectal axons to arborize at new locations during a critical period of development that ends ∼3 months postmetamorphosis (PM). Horseradish peroxidase staining of isthmotectal axons reveals that they normally run rostrocaudally in the tectum; in contrast, those axons in animals with early eye rotation have circuitous trajectories. In this paper, by studying the trajectories and branching patterns of isthmotectal axons at different times after eye rotation, we aimed to investigate when and how activity cues determine the projection pattern of isthmotectal axons. As suggested by electrophysiological recording, isthmotectal axons initially grow normally and make arbors according to activity-independent cues despite the presence of abnormal visual input. Our findings demonstrate that the development of abnormal trajectories starts by 2 weeks PM in response to eye rotation and is a protracted process. It begins in the tectal regions in which the initial connections of isthmotectal axons are first formed according to activity-independent cues. At transitional stages (5 and 10 weeks), axons with arbors at two different locations are observed, with locations corresponding to the old and new termination sites, respectively. Later, at 10 weeks of age, the fainter horseradish peroxidase staining in arbors at old termination sites suggests that the older arbors are undergoing withdrawal." @default.
• W2140397269 created "2016-06-24" @default.
• W2140397269 creator A5039729176 @default.
• W2140397269 creator A5055381354 @default.
• W2140397269 date "2000-06-01" @default.
• W2140397269 modified "2023-09-26" @default.
• W2140397269 title "The Development of Abnormal Axon Trajectories after Rotation of One Eye in<i>Xenopus</i>" @default.
• W2140397269 cites W1486903505 @default.
• W2140397269 cites W1555017510 @default.
• W2140397269 cites W1585520376 @default.
• W2140397269 cites W1601370356 @default.
• W2140397269 cites W1667808777 @default.
• W2140397269 cites W1940001296 @default.
• W2140397269 cites W1963806203 @default.
• W2140397269 cites W1967894762 @default.
• W2140397269 cites W1969097199 @default.
• W2140397269 cites W1980094138 @default.
• W2140397269 cites W1981169816 @default.
• W2140397269 cites W1982757808 @default.
• W2140397269 cites W1988490574 @default.
• W2140397269 cites W1989276676 @default.
• W2140397269 cites W1990506507 @default.
• W2140397269 cites W1991601699 @default.
• W2140397269 cites W1991878167 @default.
• W2140397269 cites W1993482929 @default.
• W2140397269 cites W1997437058 @default.
• W2140397269 cites W1998312044 @default.
• W2140397269 cites W1999912060 @default.
• W2140397269 cites W2015959352 @default.
• W2140397269 cites W2025626596 @default.
• W2140397269 cites W2032893195 @default.
• W2140397269 cites W2034105725 @default.
• W2140397269 cites W2035660891 @default.
• W2140397269 cites W2040037447 @default.
• W2140397269 cites W2041274445 @default.
• W2140397269 cites W2046729299 @default.
• W2140397269 cites W2072722219 @default.
• W2140397269 cites W2075537259 @default.
• W2140397269 cites W2085287004 @default.
• W2140397269 cites W2087248440 @default.
• W2140397269 cites W2087363824 @default.
• W2140397269 cites W2088875438 @default.
• W2140397269 cites W2132514566 @default.
• W2140397269 cites W2173013745 @default.
• W2140397269 cites W2290673031 @default.
• W2140397269 cites W2409063496 @default.
• W2140397269 cites W2575427543 @default.
• W2140397269 cites W2883830435 @default.
• W2140397269 cites W3160181233 @default.
• W2140397269 cites W4251019385 @default.
• W2140397269 cites W2092526747 @default.
• W2140397269 doi "https://doi.org/10.1523/jneurosci.20-11-04189.2000" @default.
• W2140397269 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6772623" @default.
• W2140397269 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10818154" @default.
• W2140397269 hasPublicationYear "2000" @default.
• W2140397269 type Work @default.
• W2140397269 sameAs 2140397269 @default.
• W2140397269 citedByCount "10" @default.
• W2140397269 countsByYear W21403972692012 @default.
• W2140397269 crossrefType "journal-article" @default.
• W2140397269 hasAuthorship W2140397269A5039729176 @default.
• W2140397269 hasAuthorship W2140397269A5055381354 @default.
• W2140397269 hasBestOaLocation W21403972691 @default.
• W2140397269 hasConcept C104317684 @default.
• W2140397269 hasConcept C105702510 @default.
• W2140397269 hasConcept C153050134 @default.
• W2140397269 hasConcept C169760540 @default.
• W2140397269 hasConcept C181199279 @default.
• W2140397269 hasConcept C185263204 @default.
• W2140397269 hasConcept C2777676563 @default.
• W2140397269 hasConcept C2779480072 @default.
• W2140397269 hasConcept C2779530196 @default.
• W2140397269 hasConcept C2779535977 @default.
• W2140397269 hasConcept C529278444 @default.
• W2140397269 hasConcept C54355233 @default.
• W2140397269 hasConcept C552161191 @default.
• W2140397269 hasConcept C55493867 @default.
• W2140397269 hasConcept C86803240 @default.
• W2140397269 hasConceptScore W2140397269C104317684 @default.
• W2140397269 hasConceptScore W2140397269C105702510 @default.
• W2140397269 hasConceptScore W2140397269C153050134 @default.
• W2140397269 hasConceptScore W2140397269C169760540 @default.
• W2140397269 hasConceptScore W2140397269C181199279 @default.
• W2140397269 hasConceptScore W2140397269C185263204 @default.
• W2140397269 hasConceptScore W2140397269C2777676563 @default.
• W2140397269 hasConceptScore W2140397269C2779480072 @default.
• W2140397269 hasConceptScore W2140397269C2779530196 @default.
• W2140397269 hasConceptScore W2140397269C2779535977 @default.
• W2140397269 hasConceptScore W2140397269C529278444 @default.
• W2140397269 hasConceptScore W2140397269C54355233 @default.
• W2140397269 hasConceptScore W2140397269C552161191 @default.
• W2140397269 hasConceptScore W2140397269C55493867 @default.
• W2140397269 hasConceptScore W2140397269C86803240 @default.
• W2140397269 hasIssue "11" @default.
• W2140397269 hasLocation W21403972691 @default.
• W2140397269 hasLocation W21403972692 @default.
• W2140397269 hasLocation W21403972693 @default.
• W2140397269 hasLocation W21403972694 @default.

• next