FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140400864> ?p ?o ?g. }

• W2140400864 endingPage "S105" @default.
• W2140400864 startingPage "S105" @default.
• W2140400864 abstract "ObjectiveTo characterize the maternal glycemic response to betamethasone in nondiabetic compared to diabetic subjects, and to evaluate if maternal characteristics including glucose tolerance test result prior to receipt of betamethasone predict development of significant hyperglycemia in nondiabetic gravidas.Study DesignBlood glucose levels in 22 nondiabetic and 11 diabetic pregnant subjects were recorded for 48 hours following administration of betamethasone. Maximum blood glucose value and time to maximum value was compared between groups. Area under the curve (AUC) calculations were used to express the duration and degree of significant hyperglycemia for individual subjects. These summary measures were then correlated to subject demographic and laboratory characteristics to determine a profile of the nondiabetic pregnant patient at risk for significant hyperglycemia following administration of betamethasone.ResultsThe mean maximum blood sugar value was higher for diabetics (205 mg/dL vs. 173 mg/dL, p= < 0.01), however the mean time to the maximum was not statistically different (20.4 hours vs. 26.8 hours, p= 0.16). The value of a 50 gram oral glucose tolerance test given prior to administration of betamethasone was highly correlated with the amount of time spent with significant hyperglycemia for nondiabetic subjects (rho= 0.59, p= <0.01). Morbidly obese subjects spent less time with significant hyperglycemia than those with lower body mass indices (p= 0.03).ConclusionNondiabetic pregnant subjects demonstrate significant hyperglycemia after receipt of antenatal steroids at a time when premature delivery may occur. Consideration should be given to close monitoring of the glycemic response in nondiabetics with elevated glucose tolerance testing prior to the receipt of betamethasone. ObjectiveTo characterize the maternal glycemic response to betamethasone in nondiabetic compared to diabetic subjects, and to evaluate if maternal characteristics including glucose tolerance test result prior to receipt of betamethasone predict development of significant hyperglycemia in nondiabetic gravidas. To characterize the maternal glycemic response to betamethasone in nondiabetic compared to diabetic subjects, and to evaluate if maternal characteristics including glucose tolerance test result prior to receipt of betamethasone predict development of significant hyperglycemia in nondiabetic gravidas. Study DesignBlood glucose levels in 22 nondiabetic and 11 diabetic pregnant subjects were recorded for 48 hours following administration of betamethasone. Maximum blood glucose value and time to maximum value was compared between groups. Area under the curve (AUC) calculations were used to express the duration and degree of significant hyperglycemia for individual subjects. These summary measures were then correlated to subject demographic and laboratory characteristics to determine a profile of the nondiabetic pregnant patient at risk for significant hyperglycemia following administration of betamethasone. Blood glucose levels in 22 nondiabetic and 11 diabetic pregnant subjects were recorded for 48 hours following administration of betamethasone. Maximum blood glucose value and time to maximum value was compared between groups. Area under the curve (AUC) calculations were used to express the duration and degree of significant hyperglycemia for individual subjects. These summary measures were then correlated to subject demographic and laboratory characteristics to determine a profile of the nondiabetic pregnant patient at risk for significant hyperglycemia following administration of betamethasone. ResultsThe mean maximum blood sugar value was higher for diabetics (205 mg/dL vs. 173 mg/dL, p= < 0.01), however the mean time to the maximum was not statistically different (20.4 hours vs. 26.8 hours, p= 0.16). The value of a 50 gram oral glucose tolerance test given prior to administration of betamethasone was highly correlated with the amount of time spent with significant hyperglycemia for nondiabetic subjects (rho= 0.59, p= <0.01). Morbidly obese subjects spent less time with significant hyperglycemia than those with lower body mass indices (p= 0.03). The mean maximum blood sugar value was higher for diabetics (205 mg/dL vs. 173 mg/dL, p= < 0.01), however the mean time to the maximum was not statistically different (20.4 hours vs. 26.8 hours, p= 0.16). The value of a 50 gram oral glucose tolerance test given prior to administration of betamethasone was highly correlated with the amount of time spent with significant hyperglycemia for nondiabetic subjects (rho= 0.59, p= <0.01). Morbidly obese subjects spent less time with significant hyperglycemia than those with lower body mass indices (p= 0.03). ConclusionNondiabetic pregnant subjects demonstrate significant hyperglycemia after receipt of antenatal steroids at a time when premature delivery may occur. Consideration should be given to close monitoring of the glycemic response in nondiabetics with elevated glucose tolerance testing prior to the receipt of betamethasone. Nondiabetic pregnant subjects demonstrate significant hyperglycemia after receipt of antenatal steroids at a time when premature delivery may occur. Consideration should be given to close monitoring of the glycemic response in nondiabetics with elevated glucose tolerance testing prior to the receipt of betamethasone." @default.
• W2140400864 created "2016-06-24" @default.
• W2140400864 creator A5029301272 @default.
• W2140400864 creator A5042849826 @default.
• W2140400864 creator A5054096064 @default.
• W2140400864 creator A5067224613 @default.
• W2140400864 date "2012-01-01" @default.
• W2140400864 modified "2023-10-16" @default.
• W2140400864 title "209: Effect of antenatal betamethasone on blood glucose levels in nondiabetic and diabetic gravidas" @default.
• W2140400864 doi "https://doi.org/10.1016/j.ajog.2011.10.227" @default.
• W2140400864 hasPublicationYear "2012" @default.
• W2140400864 type Work @default.
• W2140400864 sameAs 2140400864 @default.
• W2140400864 citedByCount "0" @default.
• W2140400864 crossrefType "journal-article" @default.
• W2140400864 hasAuthorship W2140400864A5029301272 @default.
• W2140400864 hasAuthorship W2140400864A5042849826 @default.
• W2140400864 hasAuthorship W2140400864A5054096064 @default.
• W2140400864 hasAuthorship W2140400864A5067224613 @default.
• W2140400864 hasConcept C126322002 @default.
• W2140400864 hasConcept C134018914 @default.
• W2140400864 hasConcept C2780473172 @default.
• W2140400864 hasConcept C2781162121 @default.
• W2140400864 hasConcept C555293320 @default.
• W2140400864 hasConcept C71924100 @default.
• W2140400864 hasConceptScore W2140400864C126322002 @default.
• W2140400864 hasConceptScore W2140400864C134018914 @default.
• W2140400864 hasConceptScore W2140400864C2780473172 @default.
• W2140400864 hasConceptScore W2140400864C2781162121 @default.
• W2140400864 hasConceptScore W2140400864C555293320 @default.
• W2140400864 hasConceptScore W2140400864C71924100 @default.
• W2140400864 hasIssue "1" @default.
• W2140400864 hasLocation W21404008641 @default.
• W2140400864 hasOpenAccess W2140400864 @default.
• W2140400864 hasPrimaryLocation W21404008641 @default.
• W2140400864 hasRelatedWork W1966504330 @default.
• W2140400864 hasRelatedWork W1979139803 @default.
• W2140400864 hasRelatedWork W2012047342 @default.
• W2140400864 hasRelatedWork W2012551297 @default.
• W2140400864 hasRelatedWork W2037631372 @default.
• W2140400864 hasRelatedWork W2040058909 @default.
• W2140400864 hasRelatedWork W2062313512 @default.
• W2140400864 hasRelatedWork W2091536151 @default.
• W2140400864 hasRelatedWork W2111497807 @default.
• W2140400864 hasRelatedWork W2748952813 @default.
• W2140400864 hasVolume "206" @default.
• W2140400864 isParatext "false" @default.
• W2140400864 isRetracted "false" @default.
• W2140400864 magId "2140400864" @default.
• W2140400864 workType "article" @default.