FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140552189> ?p ?o ?g. }

• W2140552189 endingPage "417" @default.
• W2140552189 startingPage "367" @default.
• W2140552189 abstract "There is an important interaction between the pumping performance of the ventricle, arterial haemodynamics and coronary blood flow. While previous non-linear 1D models have focused only on one of these components, the model presented in this study includes coronary and systemic arterial circulations, as well as ventricular pressure and an aortic valve that opens and closes ‘independently’ and based on local haemodynamics. The systemic circulation is modelled as a branching network of elastic tapering vessels. The terminal element applied at the extremities of the network is a single tapering vessel which is shown to adequately represent the input characteristics of the downstream vasculature. The coronary model consists of left and right coronary arteries which both branch into two ‘equivalent’ vessels that account for the lumped characteristics of subendocardial and subepicardial flows. As contracting heart muscle causes significant compression of the subendocardial vessels, a time-varying external pressure proportional to ventricular pressure is applied to the distal part of the equivalent subendocardial vessel. The aortic valve is modelled using a variable reflection coefficient with respect to backward-running aortic waves, and a variable transmission coefficient with respect to forward-running ventricular waves. A realistic ventricular pressure is the input to the system; however, an afterload-corrected ventricular pressure is calculated and results in pressure gradients between the ventricle and aorta that are similar to those observed in vivo. The 1D equations of fluid flow are solved using the locally conservative Galerkin method, which provides explicit element-wise conservation, and can naturally incorporate vessel branching. Each component of the model is verified using a number of tests to ensure accuracy and reveal the underlying processes that give rise to complex pressure and flow waveforms. The complete model is then implemented, and simulations are performed with input parameters representing ‘at rest’ and exercise states for a normal adult. The resulting waveforms contain all of the important features seen in vivo, and standard measures of haemodynamic state are found to be normal. In addition, one or several characteristics of some common diseases are imposed on the model and are found to produce haemodynamic changes that agree with experimental observations in the published literature. Using a patient-specific carotid bifurcation geometry, 1D velocity waveforms are also compared with waveforms obtained from a three-dimensional model. The 1D and 3D results show good agreement. Copyright © 2008 John Wiley & Sons, Ltd." @default.
• W2140552189 created "2016-06-24" @default.
• W2140552189 creator A5022806668 @default.
• W2140552189 creator A5034658963 @default.
• W2140552189 date "2008-03-11" @default.
• W2140552189 modified "2023-10-11" @default.
• W2140552189 title "A 1D arterial blood flow model incorporating ventricular pressure, aortic valve and regional coronary flow using the locally conservative Galerkin (LCG) method" @default.
• W2140552189 cites W1583187332 @default.
• W2140552189 cites W1782783105 @default.
• W2140552189 cites W1965973754 @default.
• W2140552189 cites W1968585604 @default.
• W2140552189 cites W1970367833 @default.
• W2140552189 cites W1972254609 @default.
• W2140552189 cites W1972591150 @default.
• W2140552189 cites W1974137970 @default.
• W2140552189 cites W1974286369 @default.
• W2140552189 cites W1975469467 @default.
• W2140552189 cites W1976047074 @default.
• W2140552189 cites W1982091732 @default.
• W2140552189 cites W1985813544 @default.
• W2140552189 cites W1994050031 @default.
• W2140552189 cites W1994514865 @default.
• W2140552189 cites W1999954866 @default.
• W2140552189 cites W2000897110 @default.
• W2140552189 cites W2007188816 @default.
• W2140552189 cites W2007838292 @default.
• W2140552189 cites W2011472183 @default.
• W2140552189 cites W2014261228 @default.
• W2140552189 cites W2015541104 @default.
• W2140552189 cites W2016214163 @default.
• W2140552189 cites W2021348557 @default.
• W2140552189 cites W2025094064 @default.
• W2140552189 cites W2025710183 @default.
• W2140552189 cites W2028161438 @default.
• W2140552189 cites W2032767423 @default.
• W2140552189 cites W2034474554 @default.
• W2140552189 cites W2036734794 @default.
• W2140552189 cites W2036745273 @default.
• W2140552189 cites W2036832512 @default.
• W2140552189 cites W2037246770 @default.
• W2140552189 cites W2038889042 @default.
• W2140552189 cites W2039362930 @default.
• W2140552189 cites W2039587866 @default.
• W2140552189 cites W2040224833 @default.
• W2140552189 cites W2041209797 @default.
• W2140552189 cites W2041472716 @default.
• W2140552189 cites W2045637452 @default.
• W2140552189 cites W2046037710 @default.
• W2140552189 cites W2048777539 @default.
• W2140552189 cites W2049730178 @default.
• W2140552189 cites W2052801507 @default.
• W2140552189 cites W2052971747 @default.
• W2140552189 cites W2056210683 @default.
• W2140552189 cites W2056352173 @default.
• W2140552189 cites W2056633584 @default.
• W2140552189 cites W2062336575 @default.
• W2140552189 cites W2062567904 @default.
• W2140552189 cites W2063619042 @default.
• W2140552189 cites W2066977652 @default.
• W2140552189 cites W2067298651 @default.
• W2140552189 cites W2070416644 @default.
• W2140552189 cites W2076444245 @default.
• W2140552189 cites W2078318670 @default.
• W2140552189 cites W2078762466 @default.
• W2140552189 cites W2081651178 @default.
• W2140552189 cites W2083476764 @default.
• W2140552189 cites W2086799842 @default.
• W2140552189 cites W2089758004 @default.
• W2140552189 cites W2090975009 @default.
• W2140552189 cites W2093505202 @default.
• W2140552189 cites W2095373768 @default.
• W2140552189 cites W2095407882 @default.
• W2140552189 cites W2097663931 @default.
• W2140552189 cites W2097847542 @default.
• W2140552189 cites W2098323358 @default.
• W2140552189 cites W2103113979 @default.
• W2140552189 cites W2107006864 @default.
• W2140552189 cites W2107983947 @default.
• W2140552189 cites W2119992348 @default.
• W2140552189 cites W2131115966 @default.
• W2140552189 cites W2133458581 @default.
• W2140552189 cites W2133680979 @default.
• W2140552189 cites W2136359902 @default.
• W2140552189 cites W2136976583 @default.
• W2140552189 cites W2140143190 @default.
• W2140552189 cites W2143381620 @default.
• W2140552189 cites W2146150343 @default.
• W2140552189 cites W2146495334 @default.
• W2140552189 cites W2150216163 @default.
• W2140552189 cites W2153937437 @default.
• W2140552189 cites W2158195166 @default.
• W2140552189 cites W2159598506 @default.
• W2140552189 cites W2159875889 @default.
• W2140552189 cites W2159998625 @default.
• W2140552189 cites W2162133926 @default.
• W2140552189 cites W2162516783 @default.
• W2140552189 cites W2167710645 @default.
• W2140552189 cites W2171116846 @default.

• next