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• W2140563246 abstract "Serotonin-1A (5-HT(1A)) receptors are known to play a role in impulsivity-related behavior. The C(-1019)G functional polymorphism (rs6295) has been suggested to regulate the 5-HT(1A) receptor gene (HTR(1A)) expression in presynaptic raphe neurons, namely, increased receptor concentration and reduced neuronal firing could be associated with the G allele. Previous studies indicate that this polymorphism is associated with aggression, suicide, and several psychiatric disorders, yet its association with impulsivity has rarely been investigated. We studied the relationship between impulsivity and the C(-1019)G polymorphism of the HTR(1A) in a population sample of 725 volunteers using the Impulsiveness subscale (IVE-I) of the Eysenck Impulsiveness, Venturesomeness, and Empathy scale and also the Barratt Impulsiveness Scale (BIS-11). Data were analyzed using analysis of variance with age and gender as covariates and Tukey's HSD post-hoc test. Post-hoc analysis revealed that the study had 0.958 power to detect 0.15 effect size. Significant differences between the C(-1019)G genotype groups (GG vs. GC vs. CC) were found. Subjects carrying GG genotype showed significantly higher impulsiveness scores compared to GC or CC carriers for the IVE-I scale (P = 0.014), for the Motor (P = 0.021), Cognitive Impulsiveness (P = 0.002), and for the BIS total score (P = 0.008) but not for the Nonplanning Impulsiveness (P = 0.520) subscale of the BIS-11. Our results suggest the involvement of the HTR(1A) in the continuum phenotype of impulsivity." @default.
• W2140563246 created "2016-06-24" @default.
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• W2140563246 date "2009-09-01" @default.
• W2140563246 modified "2023-09-27" @default.
• W2140563246 title "Significant association between the C(−1019)G functional polymorphism of the HTR_1Agene and impulsivity" @default.
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• W2140563246 cites W1980436171 @default.
• W2140563246 cites W1983336401 @default.
• W2140563246 cites W1988308733 @default.
• W2140563246 cites W1989217091 @default.
• W2140563246 cites W1989844817 @default.
• W2140563246 cites W1991438019 @default.
• W2140563246 cites W1995511712 @default.
• W2140563246 cites W2002671738 @default.
• W2140563246 cites W2002976929 @default.
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• W2140563246 cites W2010825915 @default.
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• W2140563246 cites W2014001501 @default.
• W2140563246 cites W2015920061 @default.
• W2140563246 cites W2020187940 @default.
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• W2140563246 cites W2021592118 @default.
• W2140563246 cites W2029111326 @default.
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• W2140563246 cites W2035632600 @default.
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• W2140563246 cites W2045552982 @default.
• W2140563246 cites W2046209075 @default.
• W2140563246 cites W2051376367 @default.
• W2140563246 cites W2054052132 @default.
• W2140563246 cites W2054515032 @default.
• W2140563246 cites W2055560477 @default.
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• W2140563246 doi "https://doi.org/10.1002/ajmg.b.31025" @default.
• W2140563246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19725031" @default.
• W2140563246 hasPublicationYear "2009" @default.
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