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- W2140609929 abstract "Background The use of MRI for the study of ischemia and its consequences in small animals has been limited by the need for a thoracotomy and operative occlusion of the coronary arteries. The trauma of the surgery may be an important confounder in this open-chest model. The closure of the coronaries with a suture does not allow multiple occlusion-reperfusion cycles, and has limited the study of ischemia/reperfusion in small animals. The purpose of this study was to develop a “closed chest” model of ischemia/reperfusion, which would allow ischemia and infarction to be studied in real-time while the rat is in the MRI environment." @default.
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- W2140609929 date "2012-02-01" @default.
- W2140609929 modified "2023-09-26" @default.
- W2140609929 title "A method of studying the course of myocardial ischemia and reperfusion in rats in vivo" @default.
- W2140609929 doi "https://doi.org/10.1186/1532-429x-14-s1-p58" @default.
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