Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140633405> ?p ?o ?g. }
- W2140633405 endingPage "1440" @default.
- W2140633405 startingPage "1430" @default.
- W2140633405 abstract "Tacrolimus is being increasingly used as an immunosuppressive agent in transplant recipients. The drug is metabolized by the cytochrome P-450 3A system, thus antimicrobials that inhibit or induce these enzymes can alter levels of tacrolimus in the bloodstream. Tacrolimus is potentially nephrotoxic and neurotoxic; the likelihood of toxicity rises as blood levels of the drug increase. Increased tacrolimus levels and subsequent toxicity have been produced by a number of antimicrobial agents that inhibit the cytochrome P-450 3A system. Conversely, drugs with the potential to induce the cytochrome P-450 3A system can reduce the levels of tacrolimus in the blood, leading to increased risk of acute rejection in transplant recipients. Antimicrobial agents that can have adverse effects on renal function may add to the nephrotoxicity of tacrolimus. The potential for drug interactions should be reviewed before antimicrobial agents are prescribed to patients treated with tacrolimus." @default.
- W2140633405 created "2016-06-24" @default.
- W2140633405 creator A5015076483 @default.
- W2140633405 creator A5046706963 @default.
- W2140633405 date "1997-12-01" @default.
- W2140633405 modified "2023-09-26" @default.
- W2140633405 title "Interactions Between Tacrolimus and Antimicrobial Agents" @default.
- W2140633405 cites W1563644974 @default.
- W2140633405 cites W1573393476 @default.
- W2140633405 cites W1751165781 @default.
- W2140633405 cites W1801751795 @default.
- W2140633405 cites W1833207062 @default.
- W2140633405 cites W1872591512 @default.
- W2140633405 cites W196300365 @default.
- W2140633405 cites W1968815613 @default.
- W2140633405 cites W1969355908 @default.
- W2140633405 cites W1969971113 @default.
- W2140633405 cites W1981121981 @default.
- W2140633405 cites W1985346266 @default.
- W2140633405 cites W1990171875 @default.
- W2140633405 cites W1990652438 @default.
- W2140633405 cites W1992908383 @default.
- W2140633405 cites W1997303460 @default.
- W2140633405 cites W2004273144 @default.
- W2140633405 cites W2007144355 @default.
- W2140633405 cites W2022407518 @default.
- W2140633405 cites W2024120064 @default.
- W2140633405 cites W2024312686 @default.
- W2140633405 cites W2025400695 @default.
- W2140633405 cites W2026326627 @default.
- W2140633405 cites W2027774666 @default.
- W2140633405 cites W2035982296 @default.
- W2140633405 cites W2038478347 @default.
- W2140633405 cites W2040722704 @default.
- W2140633405 cites W2043050382 @default.
- W2140633405 cites W2045137114 @default.
- W2140633405 cites W2046517531 @default.
- W2140633405 cites W2046673246 @default.
- W2140633405 cites W2048626084 @default.
- W2140633405 cites W2052489584 @default.
- W2140633405 cites W2053747884 @default.
- W2140633405 cites W2058981384 @default.
- W2140633405 cites W2063067458 @default.
- W2140633405 cites W2065470776 @default.
- W2140633405 cites W2065518515 @default.
- W2140633405 cites W2071032812 @default.
- W2140633405 cites W2072952063 @default.
- W2140633405 cites W2074227070 @default.
- W2140633405 cites W2077770154 @default.
- W2140633405 cites W2079597136 @default.
- W2140633405 cites W2080563471 @default.
- W2140633405 cites W2087204184 @default.
- W2140633405 cites W2089676317 @default.
- W2140633405 cites W2093834364 @default.
- W2140633405 cites W2105872313 @default.
- W2140633405 cites W2109378639 @default.
- W2140633405 cites W2112469703 @default.
- W2140633405 cites W2112478701 @default.
- W2140633405 cites W2122887593 @default.
- W2140633405 cites W2124780348 @default.
- W2140633405 cites W2165289393 @default.
- W2140633405 cites W2171616450 @default.
- W2140633405 cites W2224352920 @default.
- W2140633405 cites W2324657679 @default.
- W2140633405 cites W2325718923 @default.
- W2140633405 cites W2411024667 @default.
- W2140633405 cites W2411236424 @default.
- W2140633405 cites W2412641923 @default.
- W2140633405 cites W2415235022 @default.
- W2140633405 cites W2417147764 @default.
- W2140633405 cites W2417483979 @default.
- W2140633405 cites W2418028934 @default.
- W2140633405 cites W2421674954 @default.
- W2140633405 cites W2442591067 @default.
- W2140633405 cites W3025148848 @default.
- W2140633405 cites W2275247454 @default.
- W2140633405 doi "https://doi.org/10.1086/516138" @default.
- W2140633405 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9431391" @default.
- W2140633405 hasPublicationYear "1997" @default.
- W2140633405 type Work @default.
- W2140633405 sameAs 2140633405 @default.
- W2140633405 citedByCount "97" @default.
- W2140633405 countsByYear W21406334052012 @default.
- W2140633405 countsByYear W21406334052013 @default.
- W2140633405 countsByYear W21406334052014 @default.
- W2140633405 countsByYear W21406334052015 @default.
- W2140633405 countsByYear W21406334052016 @default.
- W2140633405 countsByYear W21406334052017 @default.
- W2140633405 countsByYear W21406334052018 @default.
- W2140633405 countsByYear W21406334052019 @default.
- W2140633405 countsByYear W21406334052020 @default.
- W2140633405 countsByYear W21406334052021 @default.
- W2140633405 countsByYear W21406334052022 @default.
- W2140633405 countsByYear W21406334052023 @default.
- W2140633405 crossrefType "journal-article" @default.
- W2140633405 hasAuthorship W2140633405A5015076483 @default.
- W2140633405 hasAuthorship W2140633405A5046706963 @default.
- W2140633405 hasBestOaLocation W21406334051 @default.