Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140673410> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2140673410 endingPage "87" @default.
- W2140673410 startingPage "87" @default.
- W2140673410 abstract "In vitro fertilization involves high dosage gonadotropin stimulation, which apparently has some negative impact on follicular endocrine function. As chorionic gonadotropin stimulation has been shown to increase the blood-follicular permeability in animal models, this raises the question if such an effect also applies to gonadotropins in humans, possibly affecting the endocrine follicular milieu. Follicular fluid and serum were collected at the time of follicular aspiration in in vitro fertilisation without (Natural cycle IVF, n = 24) and with (conventional gonadotropin stimulated IVF, n = 31) gonadotropin stimulation. The concentration of the extra-ovarian hormones prolactin and cortisol were analysed by immunoassays. Median serum prolactin and cortisol concentrations were 12.3 ng/mL and 399 nmol/L without versus 32.2 ng/mL and 623 nmol/L with gonadotropin stimulation. The corresponding concentrations in follicular fluid were 20.6 ng/mL and 445 nmol/L versus 28.8 ng/ml and 456 nmol/L for prolactin and cortisol. As a consequence, mean follicular fluid:serum ratios were significantly reduced under gonadotropin stimulation (prolactin p = 0.0138, cortisol p = 0.0001). As an enhanced blood-follicular permeability and transportation, induced by gonadotropin stimulation, would result in increased instead of decreased follicular fluid:serum ratios as found in this study, it can be assumed that this does not affect extra-ovarian protein and steroid hormones as illustrated by prolactin and cortisol. The model of serum follicular fluid:serum ratio of hormones, produced outside the ovaries, did not reveal a gonadotropin induced increased blood-follicular transportation capacity. Therefore it can be assumed that the effect of gonadotropins on follicular endocrine function is not due to an increased ovarian permeability of extra-ovarian hormones." @default.
- W2140673410 created "2016-06-24" @default.
- W2140673410 creator A5020284523 @default.
- W2140673410 creator A5033048768 @default.
- W2140673410 creator A5062620683 @default.
- W2140673410 creator A5068461476 @default.
- W2140673410 creator A5080990829 @default.
- W2140673410 date "2013-01-01" @default.
- W2140673410 modified "2023-10-14" @default.
- W2140673410 title "Exogenous gonadotropins do not increase the blood-follicular transportation capacity of extra-ovarian hormones such as prolactin and cortisol" @default.
- W2140673410 cites W1987865989 @default.
- W2140673410 cites W2093735285 @default.
- W2140673410 cites W2101969349 @default.
- W2140673410 cites W2121058082 @default.
- W2140673410 cites W2129807379 @default.
- W2140673410 cites W2147670254 @default.
- W2140673410 cites W2150040507 @default.
- W2140673410 cites W2165030844 @default.
- W2140673410 doi "https://doi.org/10.1186/1477-7827-11-87" @default.
- W2140673410 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3847872" @default.
- W2140673410 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24007293" @default.
- W2140673410 hasPublicationYear "2013" @default.
- W2140673410 type Work @default.
- W2140673410 sameAs 2140673410 @default.
- W2140673410 citedByCount "8" @default.
- W2140673410 countsByYear W21406734102014 @default.
- W2140673410 countsByYear W21406734102016 @default.
- W2140673410 countsByYear W21406734102017 @default.
- W2140673410 countsByYear W21406734102018 @default.
- W2140673410 countsByYear W21406734102021 @default.
- W2140673410 crossrefType "journal-article" @default.
- W2140673410 hasAuthorship W2140673410A5020284523 @default.
- W2140673410 hasAuthorship W2140673410A5033048768 @default.
- W2140673410 hasAuthorship W2140673410A5062620683 @default.
- W2140673410 hasAuthorship W2140673410A5068461476 @default.
- W2140673410 hasAuthorship W2140673410A5080990829 @default.
- W2140673410 hasBestOaLocation W21406734101 @default.
- W2140673410 hasConcept C126322002 @default.
- W2140673410 hasConcept C134018914 @default.
- W2140673410 hasConcept C187785154 @default.
- W2140673410 hasConcept C196843134 @default.
- W2140673410 hasConcept C24998067 @default.
- W2140673410 hasConcept C2775948956 @default.
- W2140673410 hasConcept C2776188440 @default.
- W2140673410 hasConcept C2776690073 @default.
- W2140673410 hasConcept C2778782382 @default.
- W2140673410 hasConcept C2779064019 @default.
- W2140673410 hasConcept C71315377 @default.
- W2140673410 hasConcept C71924100 @default.
- W2140673410 hasConcept C86803240 @default.
- W2140673410 hasConcept C95444343 @default.
- W2140673410 hasConceptScore W2140673410C126322002 @default.
- W2140673410 hasConceptScore W2140673410C134018914 @default.
- W2140673410 hasConceptScore W2140673410C187785154 @default.
- W2140673410 hasConceptScore W2140673410C196843134 @default.
- W2140673410 hasConceptScore W2140673410C24998067 @default.
- W2140673410 hasConceptScore W2140673410C2775948956 @default.
- W2140673410 hasConceptScore W2140673410C2776188440 @default.
- W2140673410 hasConceptScore W2140673410C2776690073 @default.
- W2140673410 hasConceptScore W2140673410C2778782382 @default.
- W2140673410 hasConceptScore W2140673410C2779064019 @default.
- W2140673410 hasConceptScore W2140673410C71315377 @default.
- W2140673410 hasConceptScore W2140673410C71924100 @default.
- W2140673410 hasConceptScore W2140673410C86803240 @default.
- W2140673410 hasConceptScore W2140673410C95444343 @default.
- W2140673410 hasIssue "1" @default.
- W2140673410 hasLocation W21406734101 @default.
- W2140673410 hasLocation W21406734102 @default.
- W2140673410 hasLocation W21406734103 @default.
- W2140673410 hasLocation W21406734104 @default.
- W2140673410 hasLocation W21406734105 @default.
- W2140673410 hasOpenAccess W2140673410 @default.
- W2140673410 hasPrimaryLocation W21406734101 @default.
- W2140673410 hasRelatedWork W1968130260 @default.
- W2140673410 hasRelatedWork W1995420981 @default.
- W2140673410 hasRelatedWork W2015670268 @default.
- W2140673410 hasRelatedWork W2053437304 @default.
- W2140673410 hasRelatedWork W2060618991 @default.
- W2140673410 hasRelatedWork W2074195238 @default.
- W2140673410 hasRelatedWork W2093720426 @default.
- W2140673410 hasRelatedWork W2140673410 @default.
- W2140673410 hasRelatedWork W2152306407 @default.
- W2140673410 hasRelatedWork W2416613209 @default.
- W2140673410 hasVolume "11" @default.
- W2140673410 isParatext "false" @default.
- W2140673410 isRetracted "false" @default.
- W2140673410 magId "2140673410" @default.
- W2140673410 workType "article" @default.