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- W2140677435 abstract "Over the last decade important advances have been made in our understanding of the molecular events underlying cellular responses to extracellular signals. Increased understanding of signal transduction mechanisms and gene regulation involved in immune responses has created opportunities for the discovery of novel therapeutic compounds useful in treating inflammatory disorders. One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses. Here, our current understanding of the MAP kinase pathway is reviewed, as well as recent advances in the design of novel agents that are able to modulate the activity of these signalling cascades." @default.
- W2140677435 created "2016-06-24" @default.
- W2140677435 creator A5069908102 @default.
- W2140677435 creator A5074090145 @default.
- W2140677435 creator A5087437075 @default.
- W2140677435 date "2003-01-01" @default.
- W2140677435 modified "2023-09-30" @default.
- W2140677435 title "Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets" @default.
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- W2140677435 doi "https://doi.org/10.1136/gut.52.1.144" @default.
- W2140677435 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1773518" @default.
- W2140677435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12477778" @default.
- W2140677435 hasPublicationYear "2003" @default.
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