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- W2140785510 abstract "Objectives: It reported in-stent neoatherosclerosis is a frequent finding in Drug-Eluting Stents (DES) and occurs earlier than in Bare Metal Stent (BMS) from autopsy date. But, analyses of neointimal tissue components according to the follow-up period have not been fully examined in-vivo. The aim of this study was to characterize in-stent neoatherosclerosis using radiofrequency signals from 40 MHz intravascular ultrasound (IVUS), called iMAP-IVUS.Methods: IVUS examinations were performed on 32 consecutive angina patients (32 lesions) underwent repeated PCI for the treatment of DES in-stent restenosis. We assessed neointimal tissue characteristics using iMAP-IVUS. Neointimal plaque volumes were calculated by the difference between stent and lumen volumes and coded tissue as four components; fibrous, lipidic, necrotic, and calcified. The patients were divided into two groups according to the follow-up duration: group A (≤1 year, 18 lesions) and group B (>1 year, 14 lesions).Results: Mean follow-up periods between stent implantation and repeated PCI were 21±20 months (group A: 8±2 months; group B: 37±20 months). Baseline clinical and angiographic characteristics were similar for the two groups. The percentages of fibrotic, lipidic and calcified relative volume were similar in the both group, too. However, the percentages of necrotic relative volume was greater in the group B (>1 year) than in the group A (≤1 year) (11.07% vs. 8.28%, P<0.05).![Figure][1] Figure 1Conclusions: These results suggest that in-stent neoatherosclerosis might be important mechanism of failure or very late stent thrombosis of DES. [1]: pending:yes" @default.
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- W2140785510 date "2013-08-02" @default.
- W2140785510 modified "2023-09-24" @default.
- W2140785510 title "Analysis of In-stent neoatherosclerosis after drug-eluting stent implantation using a 40 MHz intravascular ultrasound imaging system" @default.
- W2140785510 doi "https://doi.org/10.1093/eurheartj/eht309.p3960" @default.
- W2140785510 hasPublicationYear "2013" @default.
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