FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140838862> ?p ?o ?g. }

• W2140838862 endingPage "432" @default.
• W2140838862 startingPage "427" @default.
• W2140838862 abstract "Objectives: To evaluate whether the direct renin inhibitor, aliskiren, has a more favorable effect compared to amlodipine on atherosclerotic biomarkers in patients with stable coronary artery disease and diabetes currently receiving standard secondary prevention therapy. Methods: A total of 38 patients were randomly assigned initially to either aliskiren (150 mg daily) or amlodipine (5 mg daily) for 2 weeks after which the dose of either medication was increased to its maximum daily dose for 4 additional weeks. Baseline and 6-week blood samples were analyzed for changes from baseline and between treatment groups for vascular and intracellular cell adhesion molecule, C-reactive protein, nitric oxide, plasminogen activator inhibitor 1, 8-isoprostane, and thiobarbituric acid reactive substances. Results: Thirty-one patients completed the study. More of the dropouts occurred in patients receiving aliskiren. Systolic blood pressure decreased in both treatment arms with no differences between the groups being noted. Plasminogen activator inhibitor 1, nitric oxide, and C-reactive protein concentrations increased in both groups from baseline but changes from baseline or between groups were not significant. Vascular and intracellular cell adhesion molecule, thiobarbituric acid reactive substances, and isoprostane concentrations decreased in each treatment arm from baseline, but these changes were not significant and no differences were noted between the groups. Conclusions: Treatment with either aliskiren or amlodipine did not significantly alter surrogate biomarkers of atherosclerosis in patients with both diabetes and established cardiovascular disease already receiving appropriate secondary cardiovascular prevention therapy. The study is limited in its size and duration to see an effect." @default.
• W2140838862 created "2016-06-24" @default.
• W2140838862 creator A5004069438 @default.
• W2140838862 creator A5007635798 @default.
• W2140838862 creator A5012015699 @default.
• W2140838862 creator A5029844807 @default.
• W2140838862 creator A5038934174 @default.
• W2140838862 creator A5071021545 @default.
• W2140838862 creator A5091245477 @default.
• W2140838862 date "2013-05-20" @default.
• W2140838862 modified "2023-09-27" @default.
• W2140838862 title "Effects of Direct Renin Inhibition on Atherosclerotic Biomarkers in Patients With Stable Coronary Artery Disease and Type 2 Diabetes Mellitus" @default.
• W2140838862 cites W1972919038 @default.
• W2140838862 cites W1994079702 @default.
• W2140838862 cites W2000977900 @default.
• W2140838862 cites W2002270463 @default.
• W2140838862 cites W2009085960 @default.
• W2140838862 cites W2014524011 @default.
• W2140838862 cites W2018441116 @default.
• W2140838862 cites W2036585955 @default.
• W2140838862 cites W2038800901 @default.
• W2140838862 cites W2039831544 @default.
• W2140838862 cites W2066142107 @default.
• W2140838862 cites W2071637616 @default.
• W2140838862 cites W2076049791 @default.
• W2140838862 cites W2082502030 @default.
• W2140838862 cites W2085029809 @default.
• W2140838862 cites W2087944691 @default.
• W2140838862 cites W2096321722 @default.
• W2140838862 cites W2097424152 @default.
• W2140838862 cites W2107330022 @default.
• W2140838862 cites W2118795360 @default.
• W2140838862 cites W2119056313 @default.
• W2140838862 cites W2121754021 @default.
• W2140838862 cites W2122088193 @default.
• W2140838862 cites W2125966706 @default.
• W2140838862 cites W2127043863 @default.
• W2140838862 cites W2128451215 @default.
• W2140838862 cites W2131170531 @default.
• W2140838862 cites W2134318532 @default.
• W2140838862 cites W2137329488 @default.
• W2140838862 cites W2138862624 @default.
• W2140838862 cites W2139757550 @default.
• W2140838862 cites W2140172772 @default.
• W2140838862 cites W2142552310 @default.
• W2140838862 cites W2144663588 @default.
• W2140838862 cites W2145632481 @default.
• W2140838862 cites W2152798629 @default.
• W2140838862 cites W2156722540 @default.
• W2140838862 cites W2166155176 @default.
• W2140838862 cites W2167113946 @default.
• W2140838862 cites W2171818587 @default.
• W2140838862 cites W2331385536 @default.
• W2140838862 cites W3196613989 @default.
• W2140838862 doi "https://doi.org/10.1177/1074248413489772" @default.
• W2140838862 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23695772" @default.
• W2140838862 hasPublicationYear "2013" @default.
• W2140838862 type Work @default.
• W2140838862 sameAs 2140838862 @default.
• W2140838862 citedByCount "3" @default.
• W2140838862 countsByYear W21408388622015 @default.
• W2140838862 countsByYear W21408388622016 @default.
• W2140838862 crossrefType "journal-article" @default.
• W2140838862 hasAuthorship W2140838862A5004069438 @default.
• W2140838862 hasAuthorship W2140838862A5007635798 @default.
• W2140838862 hasAuthorship W2140838862A5012015699 @default.
• W2140838862 hasAuthorship W2140838862A5029844807 @default.
• W2140838862 hasAuthorship W2140838862A5038934174 @default.
• W2140838862 hasAuthorship W2140838862A5071021545 @default.
• W2140838862 hasAuthorship W2140838862A5091245477 @default.
• W2140838862 hasConcept C126322002 @default.
• W2140838862 hasConcept C134018914 @default.
• W2140838862 hasConcept C164705383 @default.
• W2140838862 hasConcept C198710026 @default.
• W2140838862 hasConcept C2778213512 @default.
• W2140838862 hasConcept C2779646130 @default.
• W2140838862 hasConcept C2779838083 @default.
• W2140838862 hasConcept C555293320 @default.
• W2140838862 hasConcept C71924100 @default.
• W2140838862 hasConcept C84393581 @default.
• W2140838862 hasConceptScore W2140838862C126322002 @default.
• W2140838862 hasConceptScore W2140838862C134018914 @default.
• W2140838862 hasConceptScore W2140838862C164705383 @default.
• W2140838862 hasConceptScore W2140838862C198710026 @default.
• W2140838862 hasConceptScore W2140838862C2778213512 @default.
• W2140838862 hasConceptScore W2140838862C2779646130 @default.
• W2140838862 hasConceptScore W2140838862C2779838083 @default.
• W2140838862 hasConceptScore W2140838862C555293320 @default.
• W2140838862 hasConceptScore W2140838862C71924100 @default.
• W2140838862 hasConceptScore W2140838862C84393581 @default.
• W2140838862 hasIssue "5" @default.
• W2140838862 hasLocation W21408388621 @default.
• W2140838862 hasLocation W21408388622 @default.
• W2140838862 hasOpenAccess W2140838862 @default.
• W2140838862 hasPrimaryLocation W21408388621 @default.
• W2140838862 hasRelatedWork W1966234050 @default.
• W2140838862 hasRelatedWork W1979286215 @default.
• W2140838862 hasRelatedWork W2038107659 @default.

• next