FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140839532> ?p ?o ?g. }

• W2140839532 endingPage "2428" @default.
• W2140839532 startingPage "2423" @default.
• W2140839532 abstract "Abstract Neuroblastoma remains responsible for a disproportionate amount of childhood cancer morbidity and mortality despite recent significant advances in understanding the genetic basis of tumor initiation and progression. About half of newly diagnosed patients can be reliably identified as having tumors of low malignant potential, and these children have cure rates of greater than 95% with little or no cytotoxic therapy. On the other hand, the other half of neuroblastomas typically present in an explosive fashion with widely metastatic disease, and reliable tumor-specific biomarkers have been defined for this phenotype as well. Empiric approaches to high-risk neuroblastoma therapy have relied on dramatic escalation of chemotherapy dose intensity and, recently, the incorporation of targeted immunotherapy, but nearly 50% of children with high-risk disease will be refractory to therapy or suffer a relapse, both of which are invariably fatal. Future improvements in high-risk neuroblastoma outcomes will require the identification of disease and patient-specific oncogenic vulnerabilities that can be leveraged therapeutically. Rational development of novel approaches to neuroblastoma therapy requires forward-thinking strategies to unequivocally prove activity in the relapse setting and, ultimately, efficacy in curing patients when integrated into frontline treatment plans. Clin Cancer Res; 18(9); 2423–8. ©2012 AACR." @default.
• W2140839532 created "2016-06-24" @default.
• W2140839532 creator A5005796905 @default.
• W2140839532 creator A5005797590 @default.
• W2140839532 date "2012-04-30" @default.
• W2140839532 modified "2023-10-14" @default.
• W2140839532 title "New Strategies in Refractory and Recurrent Neuroblastoma: Translational Opportunities to Impact Patient Outcome" @default.
• W2140839532 cites W1575002436 @default.
• W2140839532 cites W1825707388 @default.
• W2140839532 cites W1936567301 @default.
• W2140839532 cites W1951179504 @default.
• W2140839532 cites W1965605868 @default.
• W2140839532 cites W1967977447 @default.
• W2140839532 cites W1972000776 @default.
• W2140839532 cites W1982602011 @default.
• W2140839532 cites W1986157775 @default.
• W2140839532 cites W1990092992 @default.
• W2140839532 cites W2010978319 @default.
• W2140839532 cites W2011795445 @default.
• W2140839532 cites W2022354436 @default.
• W2140839532 cites W2024280594 @default.
• W2140839532 cites W2030646897 @default.
• W2140839532 cites W2035282066 @default.
• W2140839532 cites W2054051862 @default.
• W2140839532 cites W2060275730 @default.
• W2140839532 cites W2067216204 @default.
• W2140839532 cites W2073026109 @default.
• W2140839532 cites W2095849686 @default.
• W2140839532 cites W2096266806 @default.
• W2140839532 cites W2104593681 @default.
• W2140839532 cites W2104830962 @default.
• W2140839532 cites W2108541596 @default.
• W2140839532 cites W2121146521 @default.
• W2140839532 cites W2127775057 @default.
• W2140839532 cites W2129003087 @default.
• W2140839532 cites W2130465135 @default.
• W2140839532 cites W2130492852 @default.
• W2140839532 cites W2130925781 @default.
• W2140839532 cites W2136574608 @default.
• W2140839532 cites W2140032262 @default.
• W2140839532 cites W2140781632 @default.
• W2140839532 cites W2143634092 @default.
• W2140839532 cites W2144991904 @default.
• W2140839532 cites W2144999788 @default.
• W2140839532 cites W2149820950 @default.
• W2140839532 cites W2152420890 @default.
• W2140839532 cites W2153188415 @default.
• W2140839532 cites W2161707860 @default.
• W2140839532 cites W2327522594 @default.
• W2140839532 cites W2330923897 @default.
• W2140839532 cites W2334682430 @default.
• W2140839532 cites W2589841401 @default.
• W2140839532 cites W2590337937 @default.
• W2140839532 cites W4241801284 @default.
• W2140839532 cites W565993944 @default.
• W2140839532 doi "https://doi.org/10.1158/1078-0432.ccr-11-1409" @default.
• W2140839532 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3660732" @default.
• W2140839532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22427348" @default.
• W2140839532 hasPublicationYear "2012" @default.
• W2140839532 type Work @default.
• W2140839532 sameAs 2140839532 @default.
• W2140839532 citedByCount "63" @default.
• W2140839532 countsByYear W21408395322013 @default.
• W2140839532 countsByYear W21408395322014 @default.
• W2140839532 countsByYear W21408395322015 @default.
• W2140839532 countsByYear W21408395322016 @default.
• W2140839532 countsByYear W21408395322017 @default.
• W2140839532 countsByYear W21408395322018 @default.
• W2140839532 countsByYear W21408395322019 @default.
• W2140839532 countsByYear W21408395322020 @default.
• W2140839532 countsByYear W21408395322021 @default.
• W2140839532 countsByYear W21408395322022 @default.
• W2140839532 countsByYear W21408395322023 @default.
• W2140839532 crossrefType "journal-article" @default.
• W2140839532 hasAuthorship W2140839532A5005796905 @default.
• W2140839532 hasAuthorship W2140839532A5005797590 @default.
• W2140839532 hasBestOaLocation W21408395321 @default.
• W2140839532 hasConcept C121608353 @default.
• W2140839532 hasConcept C126322002 @default.
• W2140839532 hasConcept C142424586 @default.
• W2140839532 hasConcept C143998085 @default.
• W2140839532 hasConcept C177713679 @default.
• W2140839532 hasConcept C2776694085 @default.
• W2140839532 hasConcept C2776715637 @default.
• W2140839532 hasConcept C2777701055 @default.
• W2140839532 hasConcept C2779134260 @default.
• W2140839532 hasConcept C2781230642 @default.
• W2140839532 hasConcept C2993561819 @default.
• W2140839532 hasConcept C54355233 @default.
• W2140839532 hasConcept C71924100 @default.
• W2140839532 hasConcept C81885089 @default.
• W2140839532 hasConcept C86803240 @default.
• W2140839532 hasConcept C87355193 @default.
• W2140839532 hasConceptScore W2140839532C121608353 @default.
• W2140839532 hasConceptScore W2140839532C126322002 @default.
• W2140839532 hasConceptScore W2140839532C142424586 @default.
• W2140839532 hasConceptScore W2140839532C143998085 @default.
• W2140839532 hasConceptScore W2140839532C177713679 @default.

• next