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• W2140846350 abstract "In order to create a novel mechanism for herbicide resistance in plants, we expressed a single-chain antibody fragment (scFv) in tobacco with specific affinity to the auxinic herbicide picloram. Transgenic tobacco plants and seedlings expressing this scFv against picloram were protected from its effect in a dose-dependent manner. This is the first successful use of an antibody to confer in vivo resistance to a low molecular weight xenobiotic (i.e. < 1000 Da). Our results suggest the possibility for a generic antibody-based approach to create crops resistant to low molecular weight xenobiotics for subsequent use in the bioremediation of contaminated soils, crop protection and as novel selectable markers." @default.
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• W2140846350 date "2004-02-03" @default.
• W2140846350 modified "2023-10-14" @default.
• W2140846350 title "Immunomodulation confers herbicide resistance in plants" @default.
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• W2140846350 doi "https://doi.org/10.1111/j.1467-7652.2004.00060.x" @default.
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