Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140875428> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W2140875428 endingPage "244" @default.
- W2140875428 startingPage "243" @default.
- W2140875428 abstract "Received January 18, 2002; revised February 28, 2002; accepted March 5, 2002. From the Department of Psychiatry and Psychology, Cleveland Clinic Foundation, Cleveland, Ohio. Address correspondence and reprint requests to Dr. Franco, Department of Psychiatry and Psychology—P57, 9500 Euclid Avenue, Cleveland, OH 44195; E-mail: francok@ccf.org. Stiff-man syndrome (SMS) is a rare autoimmune neurological condition first described a half decade ago and only rarely spotted on consultation-liaison services. It is characterized by involuntary rigidity and painful spasm of the axial muscles, resembling a chronic form of tetanus.1–10 Patients are likened to ‘‘tin soldiers,’’2 with the following criteria: (1) initial stiffness and rigidity in the axial muscles; (2) slow progression of stiffness to include proximal limb muscles, making volitional movements and ambulation difficult; (3) a fixed deformity of the spine, as in lordosis, and with some patients a restriction of hip movement; (4) the presence of superimposed episodic spasms precipitated by sudden movements, jarring noise, and emotional upset; (5) normal findings on motor and sensory nerve examinations; (6) normal intellect; and (7) electromyographic findings typical of continuous motor activity that can be abolished by intravenous or orally administered diazepam.3,4 Antiglutamic acid decarboxylase (antiGAD65) autoantibodies disrupt the function of gammaaminobutyric acid (GABA)7 and may explain why SMS, a relapsing and remitting disease, only partially responds to diazepam and baclofen, with 50% of patients becoming wheelchair bound.2 GABA agonists, such as benzodiazepines, alcohol, and barbiturates, in high doses can greatly alleviate psychiatric and neurological symptoms.5,10,11 We describe a patient diagnosed by neurological symptoms of SMS who also met criteria for generalized anxiety, major depression, and panic disorder." @default.
- W2140875428 created "2016-06-24" @default.
- W2140875428 creator A5027904912 @default.
- W2140875428 creator A5046701250 @default.
- W2140875428 date "2002-05-01" @default.
- W2140875428 modified "2023-10-10" @default.
- W2140875428 title "Stiff-Man Syndrome: A Case Report and Review of the Literature" @default.
- W2140875428 cites W1977945926 @default.
- W2140875428 cites W1998735846 @default.
- W2140875428 cites W2006350615 @default.
- W2140875428 cites W2029863714 @default.
- W2140875428 cites W2051461206 @default.
- W2140875428 cites W2054574140 @default.
- W2140875428 cites W2065990043 @default.
- W2140875428 cites W2158184918 @default.
- W2140875428 cites W2394975342 @default.
- W2140875428 cites W2747642795 @default.
- W2140875428 doi "https://doi.org/10.1176/appi.psy.43.3.243" @default.
- W2140875428 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12075042" @default.
- W2140875428 hasPublicationYear "2002" @default.
- W2140875428 type Work @default.
- W2140875428 sameAs 2140875428 @default.
- W2140875428 citedByCount "10" @default.
- W2140875428 countsByYear W21408754282012 @default.
- W2140875428 countsByYear W21408754282013 @default.
- W2140875428 countsByYear W21408754282021 @default.
- W2140875428 crossrefType "journal-article" @default.
- W2140875428 hasAuthorship W2140875428A5027904912 @default.
- W2140875428 hasAuthorship W2140875428A5046701250 @default.
- W2140875428 hasBestOaLocation W21408754281 @default.
- W2140875428 hasConcept C15744967 @default.
- W2140875428 hasConcept C71924100 @default.
- W2140875428 hasConceptScore W2140875428C15744967 @default.
- W2140875428 hasConceptScore W2140875428C71924100 @default.
- W2140875428 hasIssue "3" @default.
- W2140875428 hasLocation W21408754281 @default.
- W2140875428 hasLocation W21408754282 @default.
- W2140875428 hasOpenAccess W2140875428 @default.
- W2140875428 hasPrimaryLocation W21408754281 @default.
- W2140875428 hasRelatedWork W1506200166 @default.
- W2140875428 hasRelatedWork W1995515455 @default.
- W2140875428 hasRelatedWork W2048182022 @default.
- W2140875428 hasRelatedWork W2080531066 @default.
- W2140875428 hasRelatedWork W2604872355 @default.
- W2140875428 hasRelatedWork W2748952813 @default.
- W2140875428 hasRelatedWork W2899084033 @default.
- W2140875428 hasRelatedWork W3031052312 @default.
- W2140875428 hasRelatedWork W3032375762 @default.
- W2140875428 hasRelatedWork W3108674512 @default.
- W2140875428 hasVolume "43" @default.
- W2140875428 isParatext "false" @default.
- W2140875428 isRetracted "false" @default.
- W2140875428 magId "2140875428" @default.
- W2140875428 workType "article" @default.