FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140921320> ?p ?o ?g. }

• W2140921320 endingPage "731" @default.
• W2140921320 startingPage "721" @default.
• W2140921320 abstract "Vaccination immunotherapies offer the promise of long-term tumor control, and preclinical trials have found promising results. Active immunotherapy uses the adaptive immune response to specifically kill tumor cells. Tumor-specific antigens are processed by antigen-presenting cells and recognized by specific effector lymphocytes. However, basic vaccination strategies with tumor lysates have been unsuccessful in inducing antiglioma immunity in clinical trials. Gliomas are known to modulate the activity of antigen-presenting cells to reduce antitumor immune activity. Recently, tumor-derived heat shock proteins have been found to more effectively activate the immune response. Widely expressed, heat shock proteins are thought to present protein peptide fragments in a format conducive to processing by antigen-presenting cells. As a part of the protein synthesis machinery, peptides complexed with heat shock proteins are effectively representative of antigens expressed by the cell; these peptides convey the specificity of this vaccination strategy. The heat shock protein–peptide vaccine is one of many promising immunotherapeutic strategies being evaluated in clinical trials. These can be broadly classified as active, passive and adoptive, each with advantages and disadvantages. Here, we compare and contrast heat shock protein–peptide vaccines with other immunotherapies and describe the outcomes of clinical trials to date." @default.
• W2140921320 created "2016-06-24" @default.
• W2140921320 creator A5011340023 @default.
• W2140921320 creator A5019650092 @default.
• W2140921320 creator A5040305872 @default.
• W2140921320 creator A5040686327 @default.
• W2140921320 creator A5054141280 @default.
• W2140921320 creator A5090727974 @default.
• W2140921320 date "2011-06-01" @default.
• W2140921320 modified "2023-10-16" @default.
• W2140921320 title "Heat shock protein–peptide complex in the treatment of glioblastoma" @default.
• W2140921320 cites W120970592 @default.
• W2140921320 cites W1558109280 @default.
• W2140921320 cites W1569077405 @default.
• W2140921320 cites W1570195799 @default.
• W2140921320 cites W1585007382 @default.
• W2140921320 cites W1956379070 @default.
• W2140921320 cites W1973505579 @default.
• W2140921320 cites W1976048867 @default.
• W2140921320 cites W1977007393 @default.
• W2140921320 cites W1979708010 @default.
• W2140921320 cites W1984324846 @default.
• W2140921320 cites W1997390346 @default.
• W2140921320 cites W1997437092 @default.
• W2140921320 cites W2000475904 @default.
• W2140921320 cites W2001544973 @default.
• W2140921320 cites W2005976617 @default.
• W2140921320 cites W2018671779 @default.
• W2140921320 cites W2032090704 @default.
• W2140921320 cites W2037218639 @default.
• W2140921320 cites W2048800818 @default.
• W2140921320 cites W2051920652 @default.
• W2140921320 cites W2060551076 @default.
• W2140921320 cites W2066562421 @default.
• W2140921320 cites W2067708969 @default.
• W2140921320 cites W2070338771 @default.
• W2140921320 cites W2071923005 @default.
• W2140921320 cites W2072861830 @default.
• W2140921320 cites W2079099131 @default.
• W2140921320 cites W2080695496 @default.
• W2140921320 cites W2083155294 @default.
• W2140921320 cites W2093199673 @default.
• W2140921320 cites W2096287682 @default.
• W2140921320 cites W2099432930 @default.
• W2140921320 cites W2099735866 @default.
• W2140921320 cites W2112645925 @default.
• W2140921320 cites W2113942802 @default.
• W2140921320 cites W2123311867 @default.
• W2140921320 cites W2124078079 @default.
• W2140921320 cites W2139008103 @default.
• W2140921320 cites W2140715248 @default.
• W2140921320 cites W2143161597 @default.
• W2140921320 cites W2144652377 @default.
• W2140921320 cites W2161216730 @default.
• W2140921320 cites W2161289668 @default.
• W2140921320 cites W2164385994 @default.
• W2140921320 cites W2166469535 @default.
• W2140921320 cites W2167414381 @default.
• W2140921320 cites W2582877258 @default.
• W2140921320 doi "https://doi.org/10.1586/erv.11.49" @default.
• W2140921320 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21692695" @default.
• W2140921320 hasPublicationYear "2011" @default.
• W2140921320 type Work @default.
• W2140921320 sameAs 2140921320 @default.
• W2140921320 citedByCount "24" @default.
• W2140921320 countsByYear W21409213202012 @default.
• W2140921320 countsByYear W21409213202013 @default.
• W2140921320 countsByYear W21409213202014 @default.
• W2140921320 countsByYear W21409213202015 @default.
• W2140921320 countsByYear W21409213202016 @default.
• W2140921320 countsByYear W21409213202017 @default.
• W2140921320 countsByYear W21409213202018 @default.
• W2140921320 countsByYear W21409213202021 @default.
• W2140921320 crossrefType "journal-article" @default.
• W2140921320 hasAuthorship W2140921320A5011340023 @default.
• W2140921320 hasAuthorship W2140921320A5019650092 @default.
• W2140921320 hasAuthorship W2140921320A5040305872 @default.
• W2140921320 hasAuthorship W2140921320A5040686327 @default.
• W2140921320 hasAuthorship W2140921320A5054141280 @default.
• W2140921320 hasAuthorship W2140921320A5090727974 @default.
• W2140921320 hasConcept C104317684 @default.
• W2140921320 hasConcept C147483822 @default.
• W2140921320 hasConcept C193419808 @default.
• W2140921320 hasConcept C203014093 @default.
• W2140921320 hasConcept C205260736 @default.
• W2140921320 hasConcept C22070199 @default.
• W2140921320 hasConcept C2776662205 @default.
• W2140921320 hasConcept C2777701055 @default.
• W2140921320 hasConcept C2779341262 @default.
• W2140921320 hasConcept C502942594 @default.
• W2140921320 hasConcept C51785407 @default.
• W2140921320 hasConcept C55493867 @default.
• W2140921320 hasConcept C71924100 @default.
• W2140921320 hasConcept C86803240 @default.
• W2140921320 hasConcept C8891405 @default.
• W2140921320 hasConceptScore W2140921320C104317684 @default.
• W2140921320 hasConceptScore W2140921320C147483822 @default.
• W2140921320 hasConceptScore W2140921320C193419808 @default.

• next