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• W2140923109 startingPage "377" @default.
• W2140923109 abstract "The dominant research subject on schizophrenia, mood disorders, autism and other central nervous system diseases has been related to neurotransmitter system abnormalities. For example, the dopamine hypothesis states that schizophrenia is the result of dopaminergic hyperactivity. The therapeutic approach has also been directed towards finding agents which will modulate or regulate these neurotransmitter systems at any step. There is substantial and mounting evidence that subtle abnormalities of reactive oxygen species (ROS) and nitric oxide (NO) may underlie a wide range of neuropsychiatric disorders. NO has chemical properties that make it uniquely suitable as an intracellular and intercellular messenger. It is produced by the activity of nitric oxide synthases which are present in peripheral tissues and in neurons. On the other hand, NO is known to be an oxygen radical in the central and peripheral nervous systems. NO has been implicated in a number of physiological functions such as noradrenaline and dopamine releases, memory and learning and certain pathologies such as schizophrenia, bipolar disorder and major depression. Evidence has been considered here for the proposal that an abnormality of NO metabolism may be a contributory factor in some neuropsychiatric disorders. The direct evidence for NO abnormalities in schizophrenia and other psychiatric disorders remains relatively limited to date, although there are some clinical and experimental studies. The suggestion that NO and other ROS may play a role in some neuropsychiatric disorders clearly has important implications for new treatment possibilities. The primary objective of the present review was to summarize and critically evaluate the current knowledge regarding a potential contribution of NO to the neuropathophysiology of schizophrenia as well as other neuropsychiatric disorders." @default.
• W2140923109 created "2016-06-24" @default.
• W2140923109 creator A5001806795 @default.
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• W2140923109 creator A5062646309 @default.
• W2140923109 date "2004-09-03" @default.
• W2140923109 modified "2023-09-29" @default.
• W2140923109 title "Nitric oxide as a physiopathological factor in neuropsychiatric disorders." @default.
• W2140923109 cites W109954717 @default.
• W2140923109 cites W113694765 @default.
• W2140923109 cites W127651725 @default.
• W2140923109 cites W1482544743 @default.
• W2140923109 cites W1520081256 @default.
• W2140923109 cites W1530199299 @default.
• W2140923109 cites W1534046497 @default.
• W2140923109 cites W1535816350 @default.
• W2140923109 cites W1573348274 @default.
• W2140923109 cites W1590567489 @default.
• W2140923109 cites W1834906675 @default.
• W2140923109 cites W1854755157 @default.
• W2140923109 cites W185592114 @default.
• W2140923109 cites W1891884171 @default.
• W2140923109 cites W1941769213 @default.
• W2140923109 cites W1952325563 @default.
• W2140923109 cites W1964671322 @default.
• W2140923109 cites W1965040374 @default.
• W2140923109 cites W1966519623 @default.
• W2140923109 cites W1969217470 @default.
• W2140923109 cites W1969673408 @default.
• W2140923109 cites W1970450248 @default.
• W2140923109 cites W1970974990 @default.
• W2140923109 cites W1973178288 @default.
• W2140923109 cites W1973558071 @default.
• W2140923109 cites W1973658948 @default.
• W2140923109 cites W1977597523 @default.
• W2140923109 cites W1978804144 @default.
• W2140923109 cites W1980237253 @default.
• W2140923109 cites W1981169658 @default.
• W2140923109 cites W1982873620 @default.
• W2140923109 cites W1986875797 @default.
• W2140923109 cites W1988210470 @default.
• W2140923109 cites W1990465763 @default.
• W2140923109 cites W1991506996 @default.
• W2140923109 cites W1993408250 @default.
• W2140923109 cites W1994151063 @default.
• W2140923109 cites W1994773641 @default.
• W2140923109 cites W1995362640 @default.
• W2140923109 cites W1995643895 @default.
• W2140923109 cites W1996015317 @default.
• W2140923109 cites W1997044687 @default.
• W2140923109 cites W1997091817 @default.
• W2140923109 cites W1998830072 @default.
• W2140923109 cites W2001986709 @default.
• W2140923109 cites W2003614392 @default.
• W2140923109 cites W2003794997 @default.
• W2140923109 cites W2003891141 @default.
• W2140923109 cites W2004780745 @default.
• W2140923109 cites W2005355701 @default.
• W2140923109 cites W2006101031 @default.
• W2140923109 cites W2007890001 @default.
• W2140923109 cites W2008649582 @default.
• W2140923109 cites W2010282997 @default.
• W2140923109 cites W2011389103 @default.
• W2140923109 cites W2012468010 @default.
• W2140923109 cites W2014109189 @default.
• W2140923109 cites W2014564436 @default.
• W2140923109 cites W2015246589 @default.
• W2140923109 cites W2018205667 @default.
• W2140923109 cites W2019594102 @default.
• W2140923109 cites W2020569812 @default.
• W2140923109 cites W2020987340 @default.
• W2140923109 cites W2022185519 @default.
• W2140923109 cites W2022473067 @default.
• W2140923109 cites W2025245489 @default.
• W2140923109 cites W2026021897 @default.
• W2140923109 cites W2028284223 @default.
• W2140923109 cites W2030654802 @default.
• W2140923109 cites W2031458689 @default.
• W2140923109 cites W2031843542 @default.
• W2140923109 cites W2034188480 @default.
• W2140923109 cites W2041197933 @default.
• W2140923109 cites W2041931361 @default.
• W2140923109 cites W2042212205 @default.
• W2140923109 cites W2042519036 @default.
• W2140923109 cites W2042828619 @default.
• W2140923109 cites W2044726203 @default.
• W2140923109 cites W2046972912 @default.
• W2140923109 cites W2047649213 @default.
• W2140923109 cites W2050431276 @default.
• W2140923109 cites W2051106202 @default.
• W2140923109 cites W2051915459 @default.
• W2140923109 cites W2052644645 @default.
• W2140923109 cites W2056666175 @default.
• W2140923109 cites W2057264210 @default.
• W2140923109 cites W2060980402 @default.
• W2140923109 cites W2065949544 @default.

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