FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2141010070> ?p ?o ?g. }

• W2141010070 endingPage "511" @default.
• W2141010070 startingPage "506" @default.
• W2141010070 abstract "PCR has greatly facilitated pertussis diagnosis due to the speed, sensitivity, and specificity of this assay compared to other detection methods. Various single-target PCR assays are currently utilized, but none is universally considered to be the gold standard. Our aim was to assess the use of multitarget versus single-target PCR for the diagnosis of pertussis in clinical samples. PCR assays targeting insertion sequence IS481 (IS), pertussis toxin ptxA promoter region (PT), and outer membrane porin (PO), or recA (RA) were evaluated in respiratory specimens collected from 4,442 patients with suspected pertussis. The diagnosis of pertussis was confirmed in 309 (6.96%) patients by the 3-target IS-PT-PO/RA PCR versus 247 (5.56%) by the conventional single-target IS (P=0.007). Compared to single-target IS, the three-target combination increased the proportion of positive specimens by 1.25-fold, and two-target combinations increased the proportion of positive specimens by 1.10- to 1.24-fold. In addition, nine cases of B. parapertussis infection were also confirmed by using the discriminative features of this multitarget PCR. Of the 89 culture-proven pertussis cases, 17 (19.1%) and 5 of the 16 patients (31.3%) admitted to intensive care unit would have been missed had only the single-target IS PCR been applied. Patients with mild disease (P=0.004) and shorter hospitalization (P=0.006) were less likely to have positive cultures. This consensus generating real-time PCR approach permits a sensitive detection, as well as an accurate species identification of the causative Bordetella pathogens for the timely management of patients." @default.
• W2141010070 created "2016-06-24" @default.
• W2141010070 creator A5000114104 @default.
• W2141010070 creator A5010848966 @default.
• W2141010070 creator A5061418945 @default.
• W2141010070 creator A5070328573 @default.
• W2141010070 date "2007-02-01" @default.
• W2141010070 modified "2023-09-27" @default.
• W2141010070 title "Multitarget PCR for Diagnosis of Pertussis and Its Clinical Implications" @default.
• W2141010070 cites W1573514861 @default.
• W2141010070 cites W1577790644 @default.
• W2141010070 cites W1786548866 @default.
• W2141010070 cites W1866797630 @default.
• W2141010070 cites W1891298982 @default.
• W2141010070 cites W1980741999 @default.
• W2141010070 cites W1986369539 @default.
• W2141010070 cites W1993942711 @default.
• W2141010070 cites W2000055267 @default.
• W2141010070 cites W2018720680 @default.
• W2141010070 cites W2024469556 @default.
• W2141010070 cites W2024688526 @default.
• W2141010070 cites W2029653765 @default.
• W2141010070 cites W2031514997 @default.
• W2141010070 cites W2048080427 @default.
• W2141010070 cites W2050229873 @default.
• W2141010070 cites W2051723450 @default.
• W2141010070 cites W2055438078 @default.
• W2141010070 cites W2082516604 @default.
• W2141010070 cites W2086433509 @default.
• W2141010070 cites W2103711483 @default.
• W2141010070 cites W2104608219 @default.
• W2141010070 cites W2110113003 @default.
• W2141010070 cites W2119016258 @default.
• W2141010070 cites W2119291968 @default.
• W2141010070 cites W2122357292 @default.
• W2141010070 cites W2132415401 @default.
• W2141010070 cites W2136945172 @default.
• W2141010070 cites W2137589065 @default.
• W2141010070 cites W2139425781 @default.
• W2141010070 cites W2142572601 @default.
• W2141010070 cites W2154817878 @default.
• W2141010070 cites W2155534524 @default.
• W2141010070 cites W2157174482 @default.
• W2141010070 cites W2164155181 @default.
• W2141010070 cites W2167342627 @default.
• W2141010070 cites W2170329452 @default.
• W2141010070 cites W2172136786 @default.
• W2141010070 cites W2188576152 @default.
• W2141010070 doi "https://doi.org/10.1128/jcm.02042-06" @default.
• W2141010070 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1829034" @default.
• W2141010070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17151210" @default.
• W2141010070 hasPublicationYear "2007" @default.
• W2141010070 type Work @default.
• W2141010070 sameAs 2141010070 @default.
• W2141010070 citedByCount "47" @default.
• W2141010070 countsByYear W21410100702012 @default.
• W2141010070 countsByYear W21410100702013 @default.
• W2141010070 countsByYear W21410100702014 @default.
• W2141010070 countsByYear W21410100702015 @default.
• W2141010070 countsByYear W21410100702016 @default.
• W2141010070 countsByYear W21410100702017 @default.
• W2141010070 countsByYear W21410100702018 @default.
• W2141010070 countsByYear W21410100702019 @default.
• W2141010070 countsByYear W21410100702020 @default.
• W2141010070 countsByYear W21410100702021 @default.
• W2141010070 countsByYear W21410100702023 @default.
• W2141010070 crossrefType "journal-article" @default.
• W2141010070 hasAuthorship W2141010070A5000114104 @default.
• W2141010070 hasAuthorship W2141010070A5010848966 @default.
• W2141010070 hasAuthorship W2141010070A5061418945 @default.
• W2141010070 hasAuthorship W2141010070A5070328573 @default.
• W2141010070 hasBestOaLocation W21410100701 @default.
• W2141010070 hasConcept C104317684 @default.
• W2141010070 hasConcept C126322002 @default.
• W2141010070 hasConcept C170493617 @default.
• W2141010070 hasConcept C203014093 @default.
• W2141010070 hasConcept C22070199 @default.
• W2141010070 hasConcept C2777582894 @default.
• W2141010070 hasConcept C2779214499 @default.
• W2141010070 hasConcept C40993552 @default.
• W2141010070 hasConcept C49105822 @default.
• W2141010070 hasConcept C49773422 @default.
• W2141010070 hasConcept C523546767 @default.
• W2141010070 hasConcept C54355233 @default.
• W2141010070 hasConcept C71924100 @default.
• W2141010070 hasConcept C80631254 @default.
• W2141010070 hasConcept C86803240 @default.
• W2141010070 hasConcept C90924648 @default.
• W2141010070 hasConceptScore W2141010070C104317684 @default.
• W2141010070 hasConceptScore W2141010070C126322002 @default.
• W2141010070 hasConceptScore W2141010070C170493617 @default.
• W2141010070 hasConceptScore W2141010070C203014093 @default.
• W2141010070 hasConceptScore W2141010070C22070199 @default.
• W2141010070 hasConceptScore W2141010070C2777582894 @default.
• W2141010070 hasConceptScore W2141010070C2779214499 @default.
• W2141010070 hasConceptScore W2141010070C40993552 @default.
• W2141010070 hasConceptScore W2141010070C49105822 @default.
• W2141010070 hasConceptScore W2141010070C49773422 @default.

• next