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• W2141036624 abstract "In mice, concomitant immunity to schistosomes seems to be largely dependent on factors that lack immunological specificity. In this review Alan Wilson describes the anatomical changes stimulated in the host's vasculature after the formation of granulomas around schistosome eggs in the liver. The blockage of portal venules by the granulomas leads to portal hypertension and the development of anastomoses that direct blood flow, schistosomula and eggs from the liver. An intact portal vasculature is required for schistosome maturation; some strains of mice appear to be resistant to schistosome infection because they have a predisposition to form anastomoses in the absence of infection." @default.
• W2141036624 created "2016-06-24" @default.
• W2141036624 creator A5079942529 @default.
• W2141036624 date "1990-01-01" @default.
• W2141036624 modified "2023-10-11" @default.
• W2141036624 title "Leaky livers, portal shunting and immunity to schistosomes" @default.
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• W2141036624 doi "https://doi.org/10.1016/0169-4758(90)90414-y" @default.
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