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• W2141093696 abstract "The basal ganglia are thought to participate in implicit sequence learning. However, the exact nature of this role has been difficult to determine in light of the conflicting evidence on implicit learning in subjects with Parkinson's disease (PD). We examined the performance of PD subjects using a modified form of the serial reaction time task, which ensured that learning remained implicit. Subjects with predominantly right-sided symptoms were trained on a 12-element sequence using the right hand. Although there was no evidence of sequence learning on the basis of response time savings, the subjects showed knowledge of the sequence when performance was assessed in terms of the number of errors made. This effect transferred to the left (untrained) hand as well. Thus, these data demonstrate that PD patients are not impaired at implicitly learning sequential order, but rather at the translation of sequence knowledge into rapid motor performance. Furthermore, the results suggest that the basal ganglia are not essential for implicit sequence learning in PD." @default.
• W2141093696 created "2016-06-24" @default.
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• W2141093696 date "2007-03-01" @default.
• W2141093696 modified "2023-10-06" @default.
• W2141093696 title "Selective impairments in implicit learning in Parkinson's disease" @default.
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• W2141093696 doi "https://doi.org/10.1016/j.brainres.2006.12.057" @default.
• W2141093696 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1865108" @default.
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