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• W2141400514 startingPage "4665" @default.
• W2141400514 abstract "We recently identified the cytoskeletal regulatory protein moesin as a novel gene that inhibits retroviral replication prior to reverse transcription by downregulation of stable microtubule formation. Here, we provide evidence that overexpression of ezrin, another closely related ezrin-radixin-moesin (ERM) family member, also blocks replication of both murine leukemia viruses and human immunodeficiency virus type 1 (HIV-1) in Rat2 fibroblasts before reverse transcription, while knockdown of endogenous ezrin increases the susceptibility of human cells to HIV-1 infection. Together, these results suggest that ERM proteins may be important determinants of retrovirus susceptibility through negative regulation of stable microtubule networks." @default.
• W2141400514 created "2016-06-24" @default.
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• W2141400514 date "2008-05-01" @default.
• W2141400514 modified "2023-10-04" @default.
• W2141400514 title "The Ezrin-Radixin-Moesin Family Member Ezrin Regulates Stable Microtubule Formation and Retroviral Infection" @default.
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• W2141400514 doi "https://doi.org/10.1128/jvi.02403-07" @default.
• W2141400514 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2293059" @default.
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• W2141400514 hasPublicationYear "2008" @default.
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