FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2141457529> ?p ?o ?g. }

• W2141457529 endingPage "276" @default.
• W2141457529 startingPage "271" @default.
• W2141457529 abstract "Background The purpose of this study is to evaluate long-term effects of spironolactone, an affordable and widely used aldosterone receptor blocker, in patients with heart failure (HF) and mild or no symptoms. Methods The study is a single-blind, placebo-controlled, blinded endpoint, randomized study. Patients with New York Heart Association (NYHA) classes I to II HF and left ventricular ejection fraction < 40% were randomized to spironolactone or placebo in addition to optimal therapy. The primary endpoint was the composite of death from any cause or cardiovascular hospitalization. Results A total of 130 patients were randomized to spironolactone (n = 65) or placebo (n = 65). Patients on spironolactone had a better event-free survival for cardiovascular death or cardiovascular hospitalizations and for cardiovascular hospitalizations alone. At multivariable analysis, only spironolactone therapy, left ventricular ejection fraction and serum creatinine levels had an independent prognostic value for the combined endpoint, whereas only spironolactone therapy and serum creatinine levels had an independent prognostic value for cardiovascular hospitalizations alone. Conclusions Administration of spironolactone reduced the composite of death and cardiovascular hospitalization in patients with NYHA classes I to II HF. These results suggest that spironolactone could be beneficial when administered on top of optimal therapy among patients with HF and mild or no symptoms." @default.
• W2141457529 created "2016-06-24" @default.
• W2141457529 creator A5000206751 @default.
• W2141457529 creator A5021758804 @default.
• W2141457529 creator A5024817912 @default.
• W2141457529 creator A5027401178 @default.
• W2141457529 creator A5053760015 @default.
• W2141457529 creator A5057572299 @default.
• W2141457529 creator A5061512474 @default.
• W2141457529 creator A5064833411 @default.
• W2141457529 creator A5077396196 @default.
• W2141457529 creator A5086713901 @default.
• W2141457529 date "2014-04-01" @default.
• W2141457529 modified "2023-10-14" @default.
• W2141457529 title "Effects of Spironolactone on Long-term Mortality and Morbidity in Patients With Heart Failure and Mild or No Symptoms" @default.
• W2141457529 cites W1964284149 @default.
• W2141457529 cites W1972482484 @default.
• W2141457529 cites W1988897145 @default.
• W2141457529 cites W2009279666 @default.
• W2141457529 cites W2012574332 @default.
• W2141457529 cites W2027163029 @default.
• W2141457529 cites W2031187741 @default.
• W2141457529 cites W2035540443 @default.
• W2141457529 cites W2058431890 @default.
• W2141457529 cites W2064854697 @default.
• W2141457529 cites W2072315913 @default.
• W2141457529 cites W2075175982 @default.
• W2141457529 cites W2090305396 @default.
• W2141457529 cites W2090544953 @default.
• W2141457529 cites W2098767714 @default.
• W2141457529 cites W2105095326 @default.
• W2141457529 cites W2109690433 @default.
• W2141457529 cites W2110392728 @default.
• W2141457529 cites W2124325536 @default.
• W2141457529 cites W2134730025 @default.
• W2141457529 cites W2134928243 @default.
• W2141457529 cites W2137306473 @default.
• W2141457529 cites W2139764595 @default.
• W2141457529 cites W2146521529 @default.
• W2141457529 cites W2146556029 @default.
• W2141457529 cites W2148910374 @default.
• W2141457529 cites W2152094259 @default.
• W2141457529 cites W2157756663 @default.
• W2141457529 cites W2164705414 @default.
• W2141457529 cites W2167010514 @default.
• W2141457529 cites W2167666858 @default.
• W2141457529 cites W2323458614 @default.
• W2141457529 cites W2469805673 @default.
• W2141457529 cites W4206632929 @default.
• W2141457529 cites W52877415 @default.
• W2141457529 doi "https://doi.org/10.1097/maj.0b013e31829dd6b1" @default.
• W2141457529 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24196866" @default.
• W2141457529 hasPublicationYear "2014" @default.
• W2141457529 type Work @default.
• W2141457529 sameAs 2141457529 @default.
• W2141457529 citedByCount "20" @default.
• W2141457529 countsByYear W21414575292014 @default.
• W2141457529 countsByYear W21414575292015 @default.
• W2141457529 countsByYear W21414575292016 @default.
• W2141457529 countsByYear W21414575292017 @default.
• W2141457529 countsByYear W21414575292018 @default.
• W2141457529 countsByYear W21414575292019 @default.
• W2141457529 countsByYear W21414575292020 @default.
• W2141457529 countsByYear W21414575292022 @default.
• W2141457529 countsByYear W21414575292023 @default.
• W2141457529 crossrefType "journal-article" @default.
• W2141457529 hasAuthorship W2141457529A5000206751 @default.
• W2141457529 hasAuthorship W2141457529A5021758804 @default.
• W2141457529 hasAuthorship W2141457529A5024817912 @default.
• W2141457529 hasAuthorship W2141457529A5027401178 @default.
• W2141457529 hasAuthorship W2141457529A5053760015 @default.
• W2141457529 hasAuthorship W2141457529A5057572299 @default.
• W2141457529 hasAuthorship W2141457529A5061512474 @default.
• W2141457529 hasAuthorship W2141457529A5064833411 @default.
• W2141457529 hasAuthorship W2141457529A5077396196 @default.
• W2141457529 hasAuthorship W2141457529A5086713901 @default.
• W2141457529 hasConcept C126322002 @default.
• W2141457529 hasConcept C142724271 @default.
• W2141457529 hasConcept C164705383 @default.
• W2141457529 hasConcept C168563851 @default.
• W2141457529 hasConcept C189135053 @default.
• W2141457529 hasConcept C203092338 @default.
• W2141457529 hasConcept C204787440 @default.
• W2141457529 hasConcept C27081682 @default.
• W2141457529 hasConcept C2776379505 @default.
• W2141457529 hasConcept C2778198053 @default.
• W2141457529 hasConcept C2778525890 @default.
• W2141457529 hasConcept C2780306776 @default.
• W2141457529 hasConcept C71924100 @default.
• W2141457529 hasConcept C78085059 @default.
• W2141457529 hasConceptScore W2141457529C126322002 @default.
• W2141457529 hasConceptScore W2141457529C142724271 @default.
• W2141457529 hasConceptScore W2141457529C164705383 @default.
• W2141457529 hasConceptScore W2141457529C168563851 @default.
• W2141457529 hasConceptScore W2141457529C189135053 @default.
• W2141457529 hasConceptScore W2141457529C203092338 @default.
• W2141457529 hasConceptScore W2141457529C204787440 @default.
• W2141457529 hasConceptScore W2141457529C27081682 @default.

• next