Matches in SemOpenAlex for { <https://semopenalex.org/work/W2141569007> ?p ?o ?g. }
- W2141569007 abstract "Francisella isolates from patients suffering from tularemia in Germany are generally strains of the species F. tularensis subsp. holarctica. To our knowledge, no other Francisella species are known for Germany. Recently, a new Francisella species could be isolated from a water reservoir of a cooling tower in Germany. We identified a Francisella sp. (isolate W12-1067) whose 16S rDNA is 99% identical to the respective nucleotide sequence of the recently published strain F. guangzhouensis. The overall sequence identity of the fopA, gyrA, rpoA, groEL, sdhA and dnaK genes is only 89%, indicating that strain W12-1067 is not identical to F. guangzhouensis. W12-1067 was isolated from a water reservoir of a cooling tower of a hospital in Germany. The growth optimum of the isolate is approximately 30°C, it can grow in the presence of 4–5% NaCl (halotolerant) and is able to grow without additional cysteine within the medium. The strain was able to replicate within a mouse-derived macrophage-like cell line. The whole genome of the strain was sequenced (~1.7 mbp, 32.2% G + C content) and the draft genome was annotated. Various virulence genes common to the genus Francisella are present, but the Francisella pathogenicity island (FPI) is missing. However, another putative type-VI secretion system is present within the genome of strain W12-1067. Isolate W12-1067 is closely related to the recently described F. guangzhouensis species and it replicates within eukaryotic host cells. Since W12-1067 exhibits a putative new type-VI secretion system and F. tularensis subsp. holarctica was found not to be the sole species in Germany, the new isolate is an interesting species to be analyzed in more detail. Further research is needed to investigate the epidemiology, ecology and pathogenicity of Francisella species present in Germany." @default.
- W2141569007 created "2016-06-24" @default.
- W2141569007 creator A5017966012 @default.
- W2141569007 creator A5018451897 @default.
- W2141569007 creator A5029571855 @default.
- W2141569007 creator A5036134061 @default.
- W2141569007 creator A5066631966 @default.
- W2141569007 creator A5068410101 @default.
- W2141569007 creator A5083666893 @default.
- W2141569007 creator A5083783156 @default.
- W2141569007 date "2014-06-25" @default.
- W2141569007 modified "2023-09-27" @default.
- W2141569007 title "Genome sequence and phenotypic analysis of a first German Francisella sp. isolate (W12-1067) not belonging to the species Francisella tularensis" @default.
- W2141569007 cites W1559209718 @default.
- W2141569007 cites W1572643137 @default.
- W2141569007 cites W1604915411 @default.
- W2141569007 cites W1606160270 @default.
- W2141569007 cites W1850013519 @default.
- W2141569007 cites W1852846064 @default.
- W2141569007 cites W1879359086 @default.
- W2141569007 cites W1882324835 @default.
- W2141569007 cites W1947628375 @default.
- W2141569007 cites W1965958122 @default.
- W2141569007 cites W1969000737 @default.
- W2141569007 cites W1970786682 @default.
- W2141569007 cites W1979152817 @default.
- W2141569007 cites W1979900370 @default.
- W2141569007 cites W1980119809 @default.
- W2141569007 cites W1985147156 @default.
- W2141569007 cites W1988101840 @default.
- W2141569007 cites W1992593677 @default.
- W2141569007 cites W1997774837 @default.
- W2141569007 cites W2004548026 @default.
- W2141569007 cites W2015183857 @default.
- W2141569007 cites W2020985296 @default.
- W2141569007 cites W2021968841 @default.
- W2141569007 cites W2022537334 @default.
- W2141569007 cites W2027644847 @default.
- W2141569007 cites W2033872995 @default.
- W2141569007 cites W2034695923 @default.
- W2141569007 cites W2035800722 @default.
- W2141569007 cites W2040330681 @default.
- W2141569007 cites W2040926474 @default.
- W2141569007 cites W2042215164 @default.
- W2141569007 cites W2046338759 @default.
- W2141569007 cites W2052093562 @default.
- W2141569007 cites W2053493806 @default.
- W2141569007 cites W2053574509 @default.
- W2141569007 cites W2057368616 @default.
- W2141569007 cites W2058054552 @default.
- W2141569007 cites W2061656821 @default.
- W2141569007 cites W2062055538 @default.
- W2141569007 cites W2062336984 @default.
- W2141569007 cites W2066567574 @default.
- W2141569007 cites W2068073783 @default.
- W2141569007 cites W2071708833 @default.
- W2141569007 cites W2072150609 @default.
- W2141569007 cites W2081427148 @default.
- W2141569007 cites W2082663122 @default.
- W2141569007 cites W2084420243 @default.
- W2141569007 cites W2088916058 @default.
- W2141569007 cites W2090084735 @default.
- W2141569007 cites W2092153134 @default.
- W2141569007 cites W2093292138 @default.
- W2141569007 cites W2094823810 @default.
- W2141569007 cites W2095791252 @default.
- W2141569007 cites W2097238956 @default.
- W2141569007 cites W2099560913 @default.
- W2141569007 cites W2099598774 @default.
- W2141569007 cites W2102789902 @default.
- W2141569007 cites W2105596396 @default.
- W2141569007 cites W2106260830 @default.
- W2141569007 cites W2108023684 @default.
- W2141569007 cites W2108275964 @default.
- W2141569007 cites W2113333497 @default.
- W2141569007 cites W2113991034 @default.
- W2141569007 cites W2114526484 @default.
- W2141569007 cites W2117041996 @default.
- W2141569007 cites W2117201736 @default.
- W2141569007 cites W2118435687 @default.
- W2141569007 cites W2121809643 @default.
- W2141569007 cites W2122592714 @default.
- W2141569007 cites W2125420227 @default.
- W2141569007 cites W2125739051 @default.
- W2141569007 cites W2127185441 @default.
- W2141569007 cites W2129136058 @default.
- W2141569007 cites W2130582802 @default.
- W2141569007 cites W2132054520 @default.
- W2141569007 cites W2132166220 @default.
- W2141569007 cites W2132396919 @default.
- W2141569007 cites W2134206955 @default.
- W2141569007 cites W2136534819 @default.
- W2141569007 cites W2136910774 @default.
- W2141569007 cites W2140228345 @default.
- W2141569007 cites W2141892017 @default.
- W2141569007 cites W2142730345 @default.
- W2141569007 cites W2143629111 @default.
- W2141569007 cites W2146927181 @default.
- W2141569007 cites W2148537746 @default.
- W2141569007 cites W2157883244 @default.