Matches in SemOpenAlex for { <https://semopenalex.org/work/W2141701467> ?p ?o ?g. }
- W2141701467 endingPage "260" @default.
- W2141701467 startingPage "253" @default.
- W2141701467 abstract "The brain is uniquely sensitive to disturbances in energy and oxygen supply, particularly during the early stage of life. Since hypoxemia can indirectly activate the intracellular messenger protein kinase C (PKC), we studied the PKCgamma-immunoreaction in the fetal hippocampal CA1 region of naive (n=4), instrumented control (n=7), and instrumented hypoxemic fetuses (n=14), at a mean gestational age of 127 days. Forty-eight hours of mild to moderate hypoxemia, were followed by a 48-h recovery period. Hypoxemia resulted in an increase in carotid blood flow (137% of control), and a shift towards a higher percentage of high-voltage electrocortical activity. After recovery, the fetal brain was fixated by perfusion of both carotid arteries, sectioned and immunostained for PKCgamma. The distribution of PKCgamma-immunoreactive cells was significantly changed after 48 h of hypoxemia in that the migration of cells (from the ventricular region towards the stratum pyramidale) was delayed (p<0.01) compared to naive and instrumented control animals. In contrast to the distribution, the relative total optical density of PKCgamma-ir cells and fibres in the CA1 hippocampal area was not significant different between the animal groups. We conclude that hypoxemia delayed migration of PKCgamma-ir cells, without neuronal degeneration." @default.
- W2141701467 created "2016-06-24" @default.
- W2141701467 creator A5019586656 @default.
- W2141701467 creator A5024510862 @default.
- W2141701467 creator A5043418440 @default.
- W2141701467 creator A5063259248 @default.
- W2141701467 creator A5087863283 @default.
- W2141701467 date "1999-05-01" @default.
- W2141701467 modified "2023-10-18" @default.
- W2141701467 title "Delayed neuronal migration of protein kinase Cγ immunoreactive cells in hippocampal CA1 area after 48 h of moderate hypoxemia in the near term ovine fetus" @default.
- W2141701467 cites W128630652 @default.
- W2141701467 cites W1452598255 @default.
- W2141701467 cites W1516468632 @default.
- W2141701467 cites W1521404049 @default.
- W2141701467 cites W1604333472 @default.
- W2141701467 cites W1943296211 @default.
- W2141701467 cites W1964371761 @default.
- W2141701467 cites W1976336392 @default.
- W2141701467 cites W1982892406 @default.
- W2141701467 cites W1986996949 @default.
- W2141701467 cites W1993384893 @default.
- W2141701467 cites W1997260013 @default.
- W2141701467 cites W1998164097 @default.
- W2141701467 cites W1998609823 @default.
- W2141701467 cites W2005239029 @default.
- W2141701467 cites W2006842487 @default.
- W2141701467 cites W2010729897 @default.
- W2141701467 cites W2014174769 @default.
- W2141701467 cites W2020622209 @default.
- W2141701467 cites W2021341799 @default.
- W2141701467 cites W2025711627 @default.
- W2141701467 cites W2027179750 @default.
- W2141701467 cites W2029625160 @default.
- W2141701467 cites W2031702150 @default.
- W2141701467 cites W2032236398 @default.
- W2141701467 cites W2035750459 @default.
- W2141701467 cites W2039761786 @default.
- W2141701467 cites W2040010868 @default.
- W2141701467 cites W2041369842 @default.
- W2141701467 cites W2053257765 @default.
- W2141701467 cites W2056550656 @default.
- W2141701467 cites W2059782821 @default.
- W2141701467 cites W2061170333 @default.
- W2141701467 cites W2067744618 @default.
- W2141701467 cites W2074939436 @default.
- W2141701467 cites W2080550745 @default.
- W2141701467 cites W2081513292 @default.
- W2141701467 cites W2086222826 @default.
- W2141701467 cites W2086603399 @default.
- W2141701467 cites W2105277370 @default.
- W2141701467 cites W2129031038 @default.
- W2141701467 cites W2130019743 @default.
- W2141701467 cites W2154779383 @default.
- W2141701467 cites W2155864261 @default.
- W2141701467 cites W2174668858 @default.
- W2141701467 doi "https://doi.org/10.1016/s0165-3806(99)00011-5" @default.
- W2141701467 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10320764" @default.
- W2141701467 hasPublicationYear "1999" @default.
- W2141701467 type Work @default.
- W2141701467 sameAs 2141701467 @default.
- W2141701467 citedByCount "8" @default.
- W2141701467 crossrefType "journal-article" @default.
- W2141701467 hasAuthorship W2141701467A5019586656 @default.
- W2141701467 hasAuthorship W2141701467A5024510862 @default.
- W2141701467 hasAuthorship W2141701467A5043418440 @default.
- W2141701467 hasAuthorship W2141701467A5063259248 @default.
- W2141701467 hasAuthorship W2141701467A5087863283 @default.
- W2141701467 hasConcept C126322002 @default.
- W2141701467 hasConcept C148762608 @default.
- W2141701467 hasConcept C169760540 @default.
- W2141701467 hasConcept C172680121 @default.
- W2141701467 hasConcept C184235292 @default.
- W2141701467 hasConcept C195794163 @default.
- W2141701467 hasConcept C2776779939 @default.
- W2141701467 hasConcept C2779234561 @default.
- W2141701467 hasConcept C54355233 @default.
- W2141701467 hasConcept C71924100 @default.
- W2141701467 hasConcept C86803240 @default.
- W2141701467 hasConcept C95444343 @default.
- W2141701467 hasConceptScore W2141701467C126322002 @default.
- W2141701467 hasConceptScore W2141701467C148762608 @default.
- W2141701467 hasConceptScore W2141701467C169760540 @default.
- W2141701467 hasConceptScore W2141701467C172680121 @default.
- W2141701467 hasConceptScore W2141701467C184235292 @default.
- W2141701467 hasConceptScore W2141701467C195794163 @default.
- W2141701467 hasConceptScore W2141701467C2776779939 @default.
- W2141701467 hasConceptScore W2141701467C2779234561 @default.
- W2141701467 hasConceptScore W2141701467C54355233 @default.
- W2141701467 hasConceptScore W2141701467C71924100 @default.
- W2141701467 hasConceptScore W2141701467C86803240 @default.
- W2141701467 hasConceptScore W2141701467C95444343 @default.
- W2141701467 hasIssue "2" @default.
- W2141701467 hasLocation W21417014671 @default.
- W2141701467 hasLocation W21417014672 @default.
- W2141701467 hasOpenAccess W2141701467 @default.
- W2141701467 hasPrimaryLocation W21417014671 @default.
- W2141701467 hasRelatedWork W1520323361 @default.
- W2141701467 hasRelatedWork W1578462026 @default.