FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2141817086> ?p ?o ?g. }

• W2141817086 endingPage "3053" @default.
• W2141817086 startingPage "3048" @default.
• W2141817086 abstract "We studied the growth-promoting effects of 2 sodium pump-selective cardiotonic steroids, ouabain and marinobufagenin, on cultured cells from vascular smooth muscle (VSMCs) from human umbilical vein and a rat VSMC line, A7r5.Both ouabain and marinobufagenin activated proliferation of these cells in a concentration-dependent manner, reflecting the cardiotonic steroid sensitivity of the specific alpha1 subunit contained within each cell source. The observed effective concentration ranges of both compounds was below that necessary to induce cytoplasmic ion alterations by sodium pump inhibition.These data indicate that the ouabain-activated proliferative effect previously observed in canine VSMCs occurs in other VSMC sources. This growth effect seems to be initiated by drug interaction with the sodium pump, reflected by the affinity of the steroid for the pump, and is independent of altered transmembrane ionic gradients." @default.
• W2141817086 created "2016-06-24" @default.
• W2141817086 creator A5003064763 @default.
• W2141817086 creator A5020579375 @default.
• W2141817086 creator A5024955198 @default.
• W2141817086 creator A5065363939 @default.
• W2141817086 creator A5068001060 @default.
• W2141817086 creator A5083990871 @default.
• W2141817086 creator A5089980629 @default.
• W2141817086 date "2003-12-16" @default.
• W2141817086 modified "2023-09-30" @default.
• W2141817086 title "Ouabain- and Marinobufagenin-Induced Proliferation of Human Umbilical Vein Smooth Muscle Cells and a Rat Vascular Smooth Muscle Cell Line, A7r5" @default.
• W2141817086 cites W1508102251 @default.
• W2141817086 cites W1598566568 @default.
• W2141817086 cites W1968320638 @default.
• W2141817086 cites W1974406064 @default.
• W2141817086 cites W1987401644 @default.
• W2141817086 cites W1998033241 @default.
• W2141817086 cites W2065804122 @default.
• W2141817086 cites W2079899892 @default.
• W2141817086 cites W2082786285 @default.
• W2141817086 cites W2116947619 @default.
• W2141817086 cites W2117667731 @default.
• W2141817086 cites W2144470409 @default.
• W2141817086 cites W2156606731 @default.
• W2141817086 cites W2162369109 @default.
• W2141817086 cites W2175631194 @default.
• W2141817086 cites W2191947373 @default.
• W2141817086 cites W2233243860 @default.
• W2141817086 cites W2325782905 @default.
• W2141817086 cites W2338021565 @default.
• W2141817086 doi "https://doi.org/10.1161/01.cir.0000101919.00548.86" @default.
• W2141817086 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14638550" @default.
• W2141817086 hasPublicationYear "2003" @default.
• W2141817086 type Work @default.
• W2141817086 sameAs 2141817086 @default.
• W2141817086 citedByCount "100" @default.
• W2141817086 countsByYear W21418170862012 @default.
• W2141817086 countsByYear W21418170862013 @default.
• W2141817086 countsByYear W21418170862014 @default.
• W2141817086 countsByYear W21418170862015 @default.
• W2141817086 countsByYear W21418170862016 @default.
• W2141817086 countsByYear W21418170862017 @default.
• W2141817086 countsByYear W21418170862018 @default.
• W2141817086 countsByYear W21418170862019 @default.
• W2141817086 countsByYear W21418170862020 @default.
• W2141817086 countsByYear W21418170862021 @default.
• W2141817086 countsByYear W21418170862022 @default.
• W2141817086 countsByYear W21418170862023 @default.
• W2141817086 crossrefType "journal-article" @default.
• W2141817086 hasAuthorship W2141817086A5003064763 @default.
• W2141817086 hasAuthorship W2141817086A5020579375 @default.
• W2141817086 hasAuthorship W2141817086A5024955198 @default.
• W2141817086 hasAuthorship W2141817086A5065363939 @default.
• W2141817086 hasAuthorship W2141817086A5068001060 @default.
• W2141817086 hasAuthorship W2141817086A5083990871 @default.
• W2141817086 hasAuthorship W2141817086A5089980629 @default.
• W2141817086 hasBestOaLocation W21418170861 @default.
• W2141817086 hasConcept C126322002 @default.
• W2141817086 hasConcept C134018914 @default.
• W2141817086 hasConcept C178790620 @default.
• W2141817086 hasConcept C185592680 @default.
• W2141817086 hasConcept C202751555 @default.
• W2141817086 hasConcept C2777411675 @default.
• W2141817086 hasConcept C2779133857 @default.
• W2141817086 hasConcept C2779395532 @default.
• W2141817086 hasConcept C2992686903 @default.
• W2141817086 hasConcept C537181965 @default.
• W2141817086 hasConcept C54355233 @default.
• W2141817086 hasConcept C55493867 @default.
• W2141817086 hasConcept C71924100 @default.
• W2141817086 hasConcept C81885089 @default.
• W2141817086 hasConcept C86803240 @default.
• W2141817086 hasConcept C95444343 @default.
• W2141817086 hasConceptScore W2141817086C126322002 @default.
• W2141817086 hasConceptScore W2141817086C134018914 @default.
• W2141817086 hasConceptScore W2141817086C178790620 @default.
• W2141817086 hasConceptScore W2141817086C185592680 @default.
• W2141817086 hasConceptScore W2141817086C202751555 @default.
• W2141817086 hasConceptScore W2141817086C2777411675 @default.
• W2141817086 hasConceptScore W2141817086C2779133857 @default.
• W2141817086 hasConceptScore W2141817086C2779395532 @default.
• W2141817086 hasConceptScore W2141817086C2992686903 @default.
• W2141817086 hasConceptScore W2141817086C537181965 @default.
• W2141817086 hasConceptScore W2141817086C54355233 @default.
• W2141817086 hasConceptScore W2141817086C55493867 @default.
• W2141817086 hasConceptScore W2141817086C71924100 @default.
• W2141817086 hasConceptScore W2141817086C81885089 @default.
• W2141817086 hasConceptScore W2141817086C86803240 @default.
• W2141817086 hasConceptScore W2141817086C95444343 @default.
• W2141817086 hasIssue "24" @default.
• W2141817086 hasLocation W21418170861 @default.
• W2141817086 hasLocation W21418170862 @default.
• W2141817086 hasOpenAccess W2141817086 @default.
• W2141817086 hasPrimaryLocation W21418170861 @default.
• W2141817086 hasRelatedWork W1548017463 @default.
• W2141817086 hasRelatedWork W2000746949 @default.
• W2141817086 hasRelatedWork W2006202112 @default.

• next