FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2141878441> ?p ?o ?g. }

• W2141878441 endingPage "1232" @default.
• W2141878441 startingPage "1224" @default.
• W2141878441 abstract "An open question in bacterial genomics is the role that adaptive evolution of the core genome plays in diversification and adaptation of bacterial species, and how this might differ between groups of bacteria occupying different environmental circumstances. The genus Campylobacter encompasses several important human and animal enteric pathogens, with genome sequence data available for eight species. We estimate the Campylobacter core genome at 647 genes, with 92.5% of the nonrecombinant core genome loci under positive selection in at least one lineage and the same gene frequently under positive selection in multiple lineages. Tests are provided that reject recombination, saturation, and variation in codon usage bias as factors contributing to this high level of selection. We suggest this genome-wide adaptive evolution may result from a Red Queen macroevolutionary dynamic, in which species are involved in competition for resources within the mammalian and/or vertebrate gastrointestinal tract. Much reduced levels of positive selection evident in Streptococcus, as reported by the authors in an earlier work, may be a consequence of these taxa inhabiting less species-rich habitats, and more unique niches. Despite many common loci under positive selection in multiple Campylobacter lineages, we found no evidence for molecular adaptive convergence at the level of the same or adjacent codons, or even protein domains. Taken collectively, these results describe the diversification of a bacterial genus that involves pervasive natural selection pressure across virtually the entire genome, with this adaptation occurring in different ways in different lineages, despite the species tendency toward a common gastrointestinal habitat." @default.
• W2141878441 created "2016-06-24" @default.
• W2141878441 creator A5051115565 @default.
• W2141878441 creator A5075292558 @default.
• W2141878441 date "2009-03-20" @default.
• W2141878441 modified "2023-09-23" @default.
• W2141878441 title "Pervasive, genome-wide positive selection leading to functional divergence in the bacterial genus <i>Campylobacter</i>" @default.
• W2141878441 cites W1596515083 @default.
• W2141878441 cites W1977039424 @default.
• W2141878441 cites W1977085329 @default.
• W2141878441 cites W1979077777 @default.
• W2141878441 cites W1982603712 @default.
• W2141878441 cites W1983297759 @default.
• W2141878441 cites W1997121998 @default.
• W2141878441 cites W2002854942 @default.
• W2141878441 cites W2003602685 @default.
• W2141878441 cites W2004552562 @default.
• W2141878441 cites W2008856488 @default.
• W2141878441 cites W2020836030 @default.
• W2141878441 cites W2025164680 @default.
• W2141878441 cites W2025253353 @default.
• W2141878441 cites W2039790548 @default.
• W2141878441 cites W2048352486 @default.
• W2141878441 cites W2052743506 @default.
• W2141878441 cites W2086103962 @default.
• W2141878441 cites W2088981436 @default.
• W2141878441 cites W2090275964 @default.
• W2141878441 cites W2097977090 @default.
• W2141878441 cites W2105585336 @default.
• W2141878441 cites W2106931934 @default.
• W2141878441 cites W2110335151 @default.
• W2141878441 cites W2112011866 @default.
• W2141878441 cites W2116433671 @default.
• W2141878441 cites W2118879505 @default.
• W2141878441 cites W2121691652 @default.
• W2141878441 cites W2125302790 @default.
• W2141878441 cites W2127641304 @default.
• W2141878441 cites W2127707752 @default.
• W2141878441 cites W2132119306 @default.
• W2141878441 cites W2132836838 @default.
• W2141878441 cites W2133585817 @default.
• W2141878441 cites W2136847298 @default.
• W2141878441 cites W2143856819 @default.
• W2141878441 cites W2144568881 @default.
• W2141878441 cites W2150550043 @default.
• W2141878441 cites W2151645494 @default.
• W2141878441 cites W2154770881 @default.
• W2141878441 cites W2156866331 @default.
• W2141878441 cites W2157267947 @default.
• W2141878441 cites W2160364329 @default.
• W2141878441 cites W2165892911 @default.
• W2141878441 cites W2166574880 @default.
• W2141878441 cites W3022728992 @default.
• W2141878441 doi "https://doi.org/10.1101/gr.089250.108" @default.
• W2141878441 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2704436" @default.
• W2141878441 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19304960" @default.
• W2141878441 hasPublicationYear "2009" @default.
• W2141878441 type Work @default.
• W2141878441 sameAs 2141878441 @default.
• W2141878441 citedByCount "66" @default.
• W2141878441 countsByYear W21418784412012 @default.
• W2141878441 countsByYear W21418784412013 @default.
• W2141878441 countsByYear W21418784412014 @default.
• W2141878441 countsByYear W21418784412015 @default.
• W2141878441 countsByYear W21418784412016 @default.
• W2141878441 countsByYear W21418784412017 @default.
• W2141878441 countsByYear W21418784412018 @default.
• W2141878441 countsByYear W21418784412019 @default.
• W2141878441 countsByYear W21418784412020 @default.
• W2141878441 countsByYear W21418784412021 @default.
• W2141878441 countsByYear W21418784412022 @default.
• W2141878441 countsByYear W21418784412023 @default.
• W2141878441 crossrefType "journal-article" @default.
• W2141878441 hasAuthorship W2141878441A5051115565 @default.
• W2141878441 hasAuthorship W2141878441A5075292558 @default.
• W2141878441 hasBestOaLocation W21418784411 @default.
• W2141878441 hasConcept C104317684 @default.
• W2141878441 hasConcept C105176652 @default.
• W2141878441 hasConcept C141231307 @default.
• W2141878441 hasConcept C154945302 @default.
• W2141878441 hasConcept C174600577 @default.
• W2141878441 hasConcept C189206191 @default.
• W2141878441 hasConcept C2776817793 @default.
• W2141878441 hasConcept C2776957140 @default.
• W2141878441 hasConcept C2779910956 @default.
• W2141878441 hasConcept C3742359 @default.
• W2141878441 hasConcept C41008148 @default.
• W2141878441 hasConcept C523546767 @default.
• W2141878441 hasConcept C54355233 @default.
• W2141878441 hasConcept C7386963 @default.
• W2141878441 hasConcept C75268714 @default.
• W2141878441 hasConcept C78458016 @default.
• W2141878441 hasConcept C81917197 @default.
• W2141878441 hasConcept C86803240 @default.
• W2141878441 hasConceptScore W2141878441C104317684 @default.
• W2141878441 hasConceptScore W2141878441C105176652 @default.
• W2141878441 hasConceptScore W2141878441C141231307 @default.
• W2141878441 hasConceptScore W2141878441C154945302 @default.

• next