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- W2141885699 abstract "ABSTRACT The results of earlier investigations that tested whether CD8 + T cells are required in the defense against Leishmania major have been inconsistent. We used CD8-deficient mice to directly address this issue. After primary infection with L. major , CD8-deficient mice controlled the infection for over 1 year and mounted strong T helper 1 cell responses. Thus, CD8 + T cells are not required for the long-term control of a primary infection with L. major ." @default.
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- W2141885699 date "1998-08-01" @default.
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- W2141885699 title "Effective and Long-Lasting Immunity against the Parasite <i>Leishmania major</i> in CD8-Deficient Mice" @default.
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- W2141885699 doi "https://doi.org/10.1128/iai.66.8.3968-3970.1998" @default.
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