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- W2141905945 abstract "Highly efficient, catalytic enantioselective synthesis of N-arylsulfonyl α-amino nitriles from the corresponding α-amido sulfones has been achieved under toluene–aqueous potassium cyanide biphasic conditions using chiral quaternary ammonium iodide (R,R,R)-1 as an effective phase-transfer catalyst. This Strecker synthesis involving the in situ generation of the reactive N-sulfonyl imines is advantageous for the cyanation of the substrates having primary and secondary alkyl substituents." @default.
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- W2141905945 date "2007-02-01" @default.
- W2141905945 modified "2023-10-17" @default.
- W2141905945 title "Advantage of in situ generation of N-arylsulfonyl imines from α-amide sulfones in the phase-transfer-catalyzed asymmetric Strecker reaction" @default.
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- W2141905945 doi "https://doi.org/10.1016/j.tetlet.2006.12.122" @default.
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