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• W2142034809 abstract "We previously showed that conjugated linoleic acid (CLA) increases 15-keto-dihydro-prostaglandin F2alpha, a marker for cyclooxygenase-mediated lipid peroxidation and thus an indicator of cyclooxygenase-mediated inflammation. The aim of the present study was to investigate the effects of CLA on other indicators of inflammation in human subjects, including C-reactive protein, TNF-alpha, TNF-alpha receptors 1 and 2, and vascular cell adhesion molecule-1. In a double-blind, placebo-controlled study, fifty-three human subjects were supplemented with a mixture (4.2 g/d) of the isomers cis-9,trans-11 CLA and trans-10,cis-12 CLA or control oil for 3 months. CLA supplementation increased levels of C-reactive protein (P=0.003) compared with the control group. However, no changes in TNF-alpha, TNF-alpha receptors 1 and 2, and vascular cell adhesion molecule-1 were detected." @default.
• W2142034809 created "2016-06-24" @default.
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• W2142034809 date "2005-11-01" @default.
• W2142034809 modified "2023-10-16" @default.
• W2142034809 title "Conjugated linoleic acid increased C-reactive protein in human subjects" @default.
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• W2142034809 doi "https://doi.org/10.1079/bjn20041419" @default.
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