Matches in SemOpenAlex for { <https://semopenalex.org/work/W2142086152> ?p ?o ?g. }
- W2142086152 endingPage "486" @default.
- W2142086152 startingPage "473" @default.
- W2142086152 abstract "Gap junctions are composed of connexin 36 (Cx36) and play a critical role in the rod photoreceptor signaling pathways of the vertebrate retina. Despite the fact that their connection and modulation in various rod pathways have been extensively studied in adult animals, little is known about the contribution and regulation of gap junctions to the development of the AII amacrine cell (AC)-mediated rod pathway. Using immunohistochemistry and microinjection, this study demonstrates a steady increase in relative Cx36 protein expression in both plexiform layers of the rabbit retina at around the time of eye opening. However, immediately after eye opening, most Cx36 immunoreactive AII ACs show no gap junction coupling pattern to neighboring cells and it is not until the third postnatal week that AII cells begin to exhibit an adult-like tracer-coupling pattern. Moreover, studies using dark-rearing and AMPA receptor blockade during postnatal development both revealed that relative levels of Cx36 immunoreactivity in AII ACs were increased when neural activity was inhibited. Our findings suggest that Cx36 expression in the AII-mediated rod pathway is activity dependent in the developing rabbit retina. © 2015 Wiley Periodicals, Inc. Develop Neurobiol 76: 473–486, 2016" @default.
- W2142086152 created "2016-06-24" @default.
- W2142086152 creator A5023684203 @default.
- W2142086152 creator A5048602474 @default.
- W2142086152 date "2015-07-01" @default.
- W2142086152 modified "2023-10-13" @default.
- W2142086152 title "Cx36 expression in the AII-mediated rod pathway is activity dependent in the developing rabbit retina" @default.
- W2142086152 cites W1482341982 @default.
- W2142086152 cites W1527411996 @default.
- W2142086152 cites W1601640976 @default.
- W2142086152 cites W1668855765 @default.
- W2142086152 cites W1733112718 @default.
- W2142086152 cites W189597957 @default.
- W2142086152 cites W1897234079 @default.
- W2142086152 cites W1908448863 @default.
- W2142086152 cites W1958166723 @default.
- W2142086152 cites W1964615063 @default.
- W2142086152 cites W1966338550 @default.
- W2142086152 cites W1968183770 @default.
- W2142086152 cites W1971277218 @default.
- W2142086152 cites W1972811274 @default.
- W2142086152 cites W1976499757 @default.
- W2142086152 cites W1976613690 @default.
- W2142086152 cites W1979696744 @default.
- W2142086152 cites W1980767795 @default.
- W2142086152 cites W1982535090 @default.
- W2142086152 cites W1983705356 @default.
- W2142086152 cites W1988175619 @default.
- W2142086152 cites W1989038219 @default.
- W2142086152 cites W1991436519 @default.
- W2142086152 cites W1994469944 @default.
- W2142086152 cites W1996609490 @default.
- W2142086152 cites W2000014452 @default.
- W2142086152 cites W2001014670 @default.
- W2142086152 cites W2006216538 @default.
- W2142086152 cites W2006595434 @default.
- W2142086152 cites W2007227176 @default.
- W2142086152 cites W2009751872 @default.
- W2142086152 cites W2010051875 @default.
- W2142086152 cites W2019818057 @default.
- W2142086152 cites W2023928955 @default.
- W2142086152 cites W2024801885 @default.
- W2142086152 cites W2025792222 @default.
- W2142086152 cites W2028196238 @default.
- W2142086152 cites W2031131256 @default.
- W2142086152 cites W2032321427 @default.
- W2142086152 cites W2037923854 @default.
- W2142086152 cites W2037959347 @default.
- W2142086152 cites W2038918053 @default.
- W2142086152 cites W2043363167 @default.
- W2142086152 cites W2056078541 @default.
- W2142086152 cites W2056798630 @default.
- W2142086152 cites W2056854592 @default.
- W2142086152 cites W2057749607 @default.
- W2142086152 cites W2063640158 @default.
- W2142086152 cites W2063787806 @default.
- W2142086152 cites W2072491375 @default.
- W2142086152 cites W2075212294 @default.
- W2142086152 cites W2075214952 @default.
- W2142086152 cites W2076711237 @default.
- W2142086152 cites W2081792794 @default.
- W2142086152 cites W2082308689 @default.
- W2142086152 cites W2082861955 @default.
- W2142086152 cites W2087898838 @default.
- W2142086152 cites W2090083858 @default.
- W2142086152 cites W2090093046 @default.
- W2142086152 cites W2090363290 @default.
- W2142086152 cites W2113270338 @default.
- W2142086152 cites W2120147866 @default.
- W2142086152 cites W2125086080 @default.
- W2142086152 cites W2127023470 @default.
- W2142086152 cites W2140532521 @default.
- W2142086152 cites W2150899253 @default.
- W2142086152 cites W2153639012 @default.
- W2142086152 cites W2160259707 @default.
- W2142086152 cites W4256268317 @default.
- W2142086152 doi "https://doi.org/10.1002/dneu.22320" @default.
- W2142086152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26084632" @default.
- W2142086152 hasPublicationYear "2015" @default.
- W2142086152 type Work @default.
- W2142086152 sameAs 2142086152 @default.
- W2142086152 citedByCount "2" @default.
- W2142086152 countsByYear W21420861522017 @default.
- W2142086152 countsByYear W21420861522023 @default.
- W2142086152 crossrefType "journal-article" @default.
- W2142086152 hasAuthorship W2142086152A5023684203 @default.
- W2142086152 hasAuthorship W2142086152A5048602474 @default.
- W2142086152 hasConcept C105702510 @default.
- W2142086152 hasConcept C126322002 @default.
- W2142086152 hasConcept C127445978 @default.
- W2142086152 hasConcept C134018914 @default.
- W2142086152 hasConcept C158157758 @default.
- W2142086152 hasConcept C169760540 @default.
- W2142086152 hasConcept C2777093970 @default.
- W2142086152 hasConcept C2780228694 @default.
- W2142086152 hasConcept C2781099447 @default.
- W2142086152 hasConcept C62525196 @default.
- W2142086152 hasConcept C71924100 @default.