FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2142110251> ?p ?o ?g. }

• W2142110251 endingPage "728" @default.
• W2142110251 startingPage "718" @default.
• W2142110251 abstract "Two human malignant mesothelioma cell sublines, one with a fibroblast‐like and the other with an epithelial differentiation, were examined for their capacity to synthesize glycosaminoglycans in the presence of IGF‐I, EGF, and their combination. This synthesis depends on the morphology of the mesothelioma cells, with many‐fold higher amounts of both hyaluronan and proteoglycans being produced by the cells with epithelial morphology than by those of the fibroblast phenotype. In both cell lines this synthesis was affected in a dose‐dependent fashion by the exogenously added growth factors and exposure to IGF‐I and EGF in combination showed a synergistic effect. This effect of those factors seems to be mediated via protein tyrosin kinase‐dependent receptors and was different in the fibroblast‐like and epithelial cells. The synthetic rates of the various glycosaminoglycans formed (hyaluronan, galactosaminoglycans and heparan sulfate) were also variously affected by these factors, indicating differences in how the synthesis of the various glycosaminoglycans is regulated. The results obtained suggest a close correlation between the presence of the appropriate growth factor(s), the process of cell differentiation and the synthesis of glycosaminoglycans in these cells." @default.
• W2142110251 created "2016-06-24" @default.
• W2142110251 creator A5003643571 @default.
• W2142110251 creator A5036240187 @default.
• W2142110251 creator A5039375722 @default.
• W2142110251 creator A5077627094 @default.
• W2142110251 date "1996-07-08" @default.
• W2142110251 modified "2023-10-02" @default.
• W2142110251 title "Effect of insulin and epidermal growth factors on the synthesis of glycosaminoglycans/proteoglycans in cultured human malignant mesothelioma cells of different phenotypic morphology" @default.
• W2142110251 cites W100847059 @default.
• W2142110251 cites W1527891330 @default.
• W2142110251 cites W1562216431 @default.
• W2142110251 cites W1658991581 @default.
• W2142110251 cites W1852034244 @default.
• W2142110251 cites W1894641937 @default.
• W2142110251 cites W1909814615 @default.
• W2142110251 cites W1974873948 @default.
• W2142110251 cites W1987563200 @default.
• W2142110251 cites W1995197844 @default.
• W2142110251 cites W1999249942 @default.
• W2142110251 cites W2005272267 @default.
• W2142110251 cites W2006641366 @default.
• W2142110251 cites W2007658152 @default.
• W2142110251 cites W2022542106 @default.
• W2142110251 cites W2041420763 @default.
• W2142110251 cites W2046135781 @default.
• W2142110251 cites W2056688540 @default.
• W2142110251 cites W2063061113 @default.
• W2142110251 cites W2070546150 @default.
• W2142110251 cites W2079022265 @default.
• W2142110251 cites W2088274902 @default.
• W2142110251 cites W2089923335 @default.
• W2142110251 cites W2092889119 @default.
• W2142110251 cites W2122715519 @default.
• W2142110251 cites W2125008790 @default.
• W2142110251 cites W2163170931 @default.
• W2142110251 cites W2174542542 @default.
• W2142110251 cites W2188060873 @default.
• W2142110251 cites W2214696477 @default.
• W2142110251 cites W2272410830 @default.
• W2142110251 cites W2281459428 @default.
• W2142110251 cites W348026187 @default.
• W2142110251 cites W4251144546 @default.
• W2142110251 cites W4376596386 @default.
• W2142110251 cites W90346617 @default.
• W2142110251 doi "https://doi.org/10.1111/j.1699-0463.1996.tb04934.x" @default.
• W2142110251 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8980622" @default.
• W2142110251 hasPublicationYear "1996" @default.
• W2142110251 type Work @default.
• W2142110251 sameAs 2142110251 @default.
• W2142110251 citedByCount "9" @default.
• W2142110251 countsByYear W21421102512014 @default.
• W2142110251 crossrefType "journal-article" @default.
• W2142110251 hasAuthorship W2142110251A5003643571 @default.
• W2142110251 hasAuthorship W2142110251A5036240187 @default.
• W2142110251 hasAuthorship W2142110251A5039375722 @default.
• W2142110251 hasAuthorship W2142110251A5077627094 @default.
• W2142110251 hasConcept C153074725 @default.
• W2142110251 hasConcept C170493617 @default.
• W2142110251 hasConcept C185592680 @default.
• W2142110251 hasConcept C2775960820 @default.
• W2142110251 hasConcept C2776362946 @default.
• W2142110251 hasConcept C2778041096 @default.
• W2142110251 hasConcept C2780381497 @default.
• W2142110251 hasConcept C54355233 @default.
• W2142110251 hasConcept C55493867 @default.
• W2142110251 hasConcept C74373430 @default.
• W2142110251 hasConcept C81885089 @default.
• W2142110251 hasConcept C86803240 @default.
• W2142110251 hasConcept C95444343 @default.
• W2142110251 hasConceptScore W2142110251C153074725 @default.
• W2142110251 hasConceptScore W2142110251C170493617 @default.
• W2142110251 hasConceptScore W2142110251C185592680 @default.
• W2142110251 hasConceptScore W2142110251C2775960820 @default.
• W2142110251 hasConceptScore W2142110251C2776362946 @default.
• W2142110251 hasConceptScore W2142110251C2778041096 @default.
• W2142110251 hasConceptScore W2142110251C2780381497 @default.
• W2142110251 hasConceptScore W2142110251C54355233 @default.
• W2142110251 hasConceptScore W2142110251C55493867 @default.
• W2142110251 hasConceptScore W2142110251C74373430 @default.
• W2142110251 hasConceptScore W2142110251C81885089 @default.
• W2142110251 hasConceptScore W2142110251C86803240 @default.
• W2142110251 hasConceptScore W2142110251C95444343 @default.
• W2142110251 hasIssue "7-8" @default.
• W2142110251 hasLocation W21421102511 @default.
• W2142110251 hasLocation W21421102512 @default.
• W2142110251 hasOpenAccess W2142110251 @default.
• W2142110251 hasPrimaryLocation W21421102511 @default.
• W2142110251 hasRelatedWork W2024268683 @default.
• W2142110251 hasRelatedWork W2032784439 @default.
• W2142110251 hasRelatedWork W2057328263 @default.
• W2142110251 hasRelatedWork W2059274898 @default.
• W2142110251 hasRelatedWork W2075625336 @default.
• W2142110251 hasRelatedWork W2077996870 @default.
• W2142110251 hasRelatedWork W2089923335 @default.
• W2142110251 hasRelatedWork W2142110251 @default.
• W2142110251 hasRelatedWork W2159041180 @default.
• W2142110251 hasRelatedWork W2973215277 @default.

• next