Matches in SemOpenAlex for { <https://semopenalex.org/work/W2142183601> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2142183601 endingPage "862" @default.
- W2142183601 startingPage "858" @default.
- W2142183601 abstract "Food-borne trematodiasis is an emerging public health problem with more than 10% of the world's population at risk of infection, yet there are only 2 drugs available for treatment and morbidity control. We assessed the effect of a promising broad-spectrum anthelmintic drug, i.e., tribendimidine, with an experimental focus on adult Echinostoma caproni. Female NMRI mice were infected with 30 E. caproni for 2 wk and then administered single oral doses of tribendimidine ranging between 25 and 500 mg/kg. Three days post-treatment, mice were necropsied, and adult worms were recovered from their intestines. Worm burden reductions were assessed against untreated control mice. In addition, scanning electron microscopic observations were done on adult E. caproni recovered from mice given a single dose of 150 mg/kg tribendimidine intragastrically 2, 4, and 8 hr post-treatment. Worm burden reductions of 100% were achieved at doses of 125 mg/kg and above. Severe damage of the tegument, including extensive peeling, formation of blebs, and structural loss of the definition of collar and tegumentary spines already occurred within 2 hr after drug administration. Our findings call for further investigations using tribendimidine in other trematode-animal models, because this compound shows promising trematocidal activity." @default.
- W2142183601 created "2016-06-24" @default.
- W2142183601 creator A5004103610 @default.
- W2142183601 creator A5015991419 @default.
- W2142183601 creator A5033452459 @default.
- W2142183601 date "2006-08-01" @default.
- W2142183601 modified "2023-09-25" @default.
- W2142183601 title "EFFECT OF TRIBENDIMIDINE ON ADULT ECHINOSTOMA CAPRONI HARBORED IN MICE, INCLUDING SCANNING ELECTRON MICROSCOPIC OBSERVATIONS" @default.
- W2142183601 cites W1763319754 @default.
- W2142183601 cites W1965609285 @default.
- W2142183601 cites W2023552484 @default.
- W2142183601 cites W2039428342 @default.
- W2142183601 cites W2061703004 @default.
- W2142183601 cites W2062750423 @default.
- W2142183601 cites W2063740108 @default.
- W2142183601 cites W2083109054 @default.
- W2142183601 cites W2092160057 @default.
- W2142183601 cites W2092562689 @default.
- W2142183601 cites W2096117384 @default.
- W2142183601 cites W2134575926 @default.
- W2142183601 cites W2158723210 @default.
- W2142183601 doi "https://doi.org/10.1645/ge-793r.1" @default.
- W2142183601 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16995405" @default.
- W2142183601 hasPublicationYear "2006" @default.
- W2142183601 type Work @default.
- W2142183601 sameAs 2142183601 @default.
- W2142183601 citedByCount "18" @default.
- W2142183601 countsByYear W21421836012012 @default.
- W2142183601 countsByYear W21421836012013 @default.
- W2142183601 countsByYear W21421836012014 @default.
- W2142183601 countsByYear W21421836012018 @default.
- W2142183601 crossrefType "journal-article" @default.
- W2142183601 hasAuthorship W2142183601A5004103610 @default.
- W2142183601 hasAuthorship W2142183601A5015991419 @default.
- W2142183601 hasAuthorship W2142183601A5033452459 @default.
- W2142183601 hasConcept C146998594 @default.
- W2142183601 hasConcept C159047783 @default.
- W2142183601 hasConcept C2776908094 @default.
- W2142183601 hasConcept C2908647359 @default.
- W2142183601 hasConcept C42407357 @default.
- W2142183601 hasConcept C71924100 @default.
- W2142183601 hasConcept C86803240 @default.
- W2142183601 hasConcept C90856448 @default.
- W2142183601 hasConcept C98274493 @default.
- W2142183601 hasConcept C99454951 @default.
- W2142183601 hasConceptScore W2142183601C146998594 @default.
- W2142183601 hasConceptScore W2142183601C159047783 @default.
- W2142183601 hasConceptScore W2142183601C2776908094 @default.
- W2142183601 hasConceptScore W2142183601C2908647359 @default.
- W2142183601 hasConceptScore W2142183601C42407357 @default.
- W2142183601 hasConceptScore W2142183601C71924100 @default.
- W2142183601 hasConceptScore W2142183601C86803240 @default.
- W2142183601 hasConceptScore W2142183601C90856448 @default.
- W2142183601 hasConceptScore W2142183601C98274493 @default.
- W2142183601 hasConceptScore W2142183601C99454951 @default.
- W2142183601 hasIssue "4" @default.
- W2142183601 hasLocation W21421836011 @default.
- W2142183601 hasLocation W21421836012 @default.
- W2142183601 hasOpenAccess W2142183601 @default.
- W2142183601 hasPrimaryLocation W21421836011 @default.
- W2142183601 hasRelatedWork W1614581804 @default.
- W2142183601 hasRelatedWork W2030019381 @default.
- W2142183601 hasRelatedWork W2046739471 @default.
- W2142183601 hasRelatedWork W2088062465 @default.
- W2142183601 hasRelatedWork W2256089770 @default.
- W2142183601 hasRelatedWork W2412816124 @default.
- W2142183601 hasRelatedWork W2745736500 @default.
- W2142183601 hasRelatedWork W2993351644 @default.
- W2142183601 hasRelatedWork W3027666029 @default.
- W2142183601 hasRelatedWork W2344399163 @default.
- W2142183601 hasVolume "92" @default.
- W2142183601 isParatext "false" @default.
- W2142183601 isRetracted "false" @default.
- W2142183601 magId "2142183601" @default.
- W2142183601 workType "article" @default.