Matches in SemOpenAlex for { <https://semopenalex.org/work/W2142238897> ?p ?o ?g. }
- W2142238897 endingPage "663" @default.
- W2142238897 startingPage "657" @default.
- W2142238897 abstract "The potential benefit of hyaluronans in alleviating pain associated with osteoarthritis (OA) in joints other than the knee is of increasing interest. This double-blind, randomized, controlled study examined the safety and efficacy of intraarticular sodium hyaluronate (Hyalgan) in the treatment of pain associated with ankle OA.Thirty consecutive patients with ankle OA documented by X-ray were randomized to treatment with five weekly injections of either sodium hyaluronate 2 mL (HYL) or phosphate-buffered saline 2 mL (control) in the tibiotalar joint. The primary endpoint was pain on movement and weightbearing using the Ankle Osteoarthritis Scale (AOS) 3 months after injection (a 100-mm visual analog scale [VAS]). Additional measures included the Western Ontario and McMaster Universities (WOMAC) OA Index and patient global assessment through 6 months; the Short Form-12 (SF-12) Health Survey at 3 months and 6 months; and all reported adverse events (AEs).The study groups differed only in age, baseline WOMAC pain, and AOS total scores; 80% of the HYL and 73% of the control patients completed the study. At Month 3, the primary endpoint of the study, the HYL group demonstrated a significantly greater improvement from baseline in AOS total score than did the control group (HYL: -17.4 +/- 5.0 mm;-5.1 +/- 4.0 mm; p = 0.0407). The incidence of AEs was low, with no significant differences between the groups. There were no post-injection flares.Our study suggests that sodium hyaluronate may be a safe and effective option for pain associated with ankle OA, although larger studies are needed." @default.
- W2142238897 created "2016-06-24" @default.
- W2142238897 creator A5021040304 @default.
- W2142238897 creator A5031970656 @default.
- W2142238897 creator A5047470226 @default.
- W2142238897 creator A5065748696 @default.
- W2142238897 creator A5071031488 @default.
- W2142238897 creator A5089219499 @default.
- W2142238897 date "2008-07-01" @default.
- W2142238897 modified "2023-10-14" @default.
- W2142238897 title "Safety and Efficacy of Intra-articular Sodium Hyaluronate (Hyalgan<sup>®</sup>) in a Randomized, Double-Blind Study for Osteoarthritis of the Ankle" @default.
- W2142238897 cites W1967057044 @default.
- W2142238897 cites W1979403242 @default.
- W2142238897 cites W1989562112 @default.
- W2142238897 cites W1991461457 @default.
- W2142238897 cites W2047707946 @default.
- W2142238897 cites W2064512855 @default.
- W2142238897 cites W2084222669 @default.
- W2142238897 cites W2112755074 @default.
- W2142238897 cites W2115671833 @default.
- W2142238897 cites W2139519103 @default.
- W2142238897 cites W2159126988 @default.
- W2142238897 cites W2174647847 @default.
- W2142238897 cites W2316972231 @default.
- W2142238897 cites W3022341518 @default.
- W2142238897 cites W4298157142 @default.
- W2142238897 doi "https://doi.org/10.3113/fai.2008.0657" @default.
- W2142238897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18785414" @default.
- W2142238897 hasPublicationYear "2008" @default.
- W2142238897 type Work @default.
- W2142238897 sameAs 2142238897 @default.
- W2142238897 citedByCount "94" @default.
- W2142238897 countsByYear W21422388972012 @default.
- W2142238897 countsByYear W21422388972013 @default.
- W2142238897 countsByYear W21422388972014 @default.
- W2142238897 countsByYear W21422388972015 @default.
- W2142238897 countsByYear W21422388972016 @default.
- W2142238897 countsByYear W21422388972017 @default.
- W2142238897 countsByYear W21422388972018 @default.
- W2142238897 countsByYear W21422388972019 @default.
- W2142238897 countsByYear W21422388972020 @default.
- W2142238897 countsByYear W21422388972021 @default.
- W2142238897 countsByYear W21422388972022 @default.
- W2142238897 countsByYear W21422388972023 @default.
- W2142238897 crossrefType "journal-article" @default.
- W2142238897 hasAuthorship W2142238897A5021040304 @default.
- W2142238897 hasAuthorship W2142238897A5031970656 @default.
- W2142238897 hasAuthorship W2142238897A5047470226 @default.
- W2142238897 hasAuthorship W2142238897A5065748696 @default.
- W2142238897 hasAuthorship W2142238897A5071031488 @default.
- W2142238897 hasAuthorship W2142238897A5089219499 @default.
- W2142238897 hasConcept C126322002 @default.
- W2142238897 hasConcept C141071460 @default.
- W2142238897 hasConcept C14184104 @default.
- W2142238897 hasConcept C142724271 @default.
- W2142238897 hasConcept C168563851 @default.
- W2142238897 hasConcept C1862650 @default.
- W2142238897 hasConcept C197934379 @default.
- W2142238897 hasConcept C203092338 @default.
- W2142238897 hasConcept C204787440 @default.
- W2142238897 hasConcept C2776164576 @default.
- W2142238897 hasConcept C2777917749 @default.
- W2142238897 hasConcept C2778640784 @default.
- W2142238897 hasConcept C2779286237 @default.
- W2142238897 hasConcept C2909830753 @default.
- W2142238897 hasConcept C3019843197 @default.
- W2142238897 hasConcept C71924100 @default.
- W2142238897 hasConceptScore W2142238897C126322002 @default.
- W2142238897 hasConceptScore W2142238897C141071460 @default.
- W2142238897 hasConceptScore W2142238897C14184104 @default.
- W2142238897 hasConceptScore W2142238897C142724271 @default.
- W2142238897 hasConceptScore W2142238897C168563851 @default.
- W2142238897 hasConceptScore W2142238897C1862650 @default.
- W2142238897 hasConceptScore W2142238897C197934379 @default.
- W2142238897 hasConceptScore W2142238897C203092338 @default.
- W2142238897 hasConceptScore W2142238897C204787440 @default.
- W2142238897 hasConceptScore W2142238897C2776164576 @default.
- W2142238897 hasConceptScore W2142238897C2777917749 @default.
- W2142238897 hasConceptScore W2142238897C2778640784 @default.
- W2142238897 hasConceptScore W2142238897C2779286237 @default.
- W2142238897 hasConceptScore W2142238897C2909830753 @default.
- W2142238897 hasConceptScore W2142238897C3019843197 @default.
- W2142238897 hasConceptScore W2142238897C71924100 @default.
- W2142238897 hasIssue "7" @default.
- W2142238897 hasLocation W21422388971 @default.
- W2142238897 hasLocation W21422388972 @default.
- W2142238897 hasOpenAccess W2142238897 @default.
- W2142238897 hasPrimaryLocation W21422388971 @default.
- W2142238897 hasRelatedWork W2036435359 @default.
- W2142238897 hasRelatedWork W2081936818 @default.
- W2142238897 hasRelatedWork W2098222112 @default.
- W2142238897 hasRelatedWork W2383683641 @default.
- W2142238897 hasRelatedWork W2560792941 @default.
- W2142238897 hasRelatedWork W2576737981 @default.
- W2142238897 hasRelatedWork W2797061458 @default.
- W2142238897 hasRelatedWork W2809547195 @default.
- W2142238897 hasRelatedWork W2993574397 @default.
- W2142238897 hasRelatedWork W3187189475 @default.