Matches in SemOpenAlex for { <https://semopenalex.org/work/W2142325714> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2142325714 endingPage "701" @default.
- W2142325714 startingPage "697" @default.
- W2142325714 abstract "Evaluation of HIV-induced IL-2 production by peripheral blood mononuclear cells (PBMC) and HIV-specific T helper and cytotoxic T lymphocyte (CTL) responses in health care workers (HCW) occupationally exposed to HIV reveals a high rate of response to HIV among non-seroconverters. IL-10 is also known to interfere with HIV infection in vitro. To evaluate the induction of IL-10 by HIV antigens in HCW occupationally exposed to HIV, 18 HCW with percutaneous injury were enrolled in this study, 9 of them exposed to HIV-contaminated blood, and 9 exposed to HIV-negative blood. PBMC were incubated on plates coated with HIV-1 antigens, and IL-10 was measured in supernatants by ELISA. Five of nine HCW exposed to HIV-contaminated blood presented HIV-induced IL-10. Two of nine HCW exposed to HIV-negative source patients also had detectable levels of HIV-induced IL-10, one of them in the sample obtained on the day of accidental exposure. There was a relationship between the type of device involved in injury and IL-10 production. Individuals exposed to hollow needles or scalpels presented HIV-induced IL-10, whereas those exposed to solid needles and to digital puncture did not, suggesting a relationship between infectious load and IL-10. Although occupational exposure to HIV leads to a low rate of seroconversion, these individuals can develop an antigen-specific immune response characterized in our study by induction of IL-10 in PBMC in vitro." @default.
- W2142325714 created "2016-06-24" @default.
- W2142325714 creator A5024588860 @default.
- W2142325714 creator A5025542473 @default.
- W2142325714 creator A5030844937 @default.
- W2142325714 creator A5044529313 @default.
- W2142325714 creator A5079261852 @default.
- W2142325714 creator A5079615499 @default.
- W2142325714 date "2002-06-01" @default.
- W2142325714 modified "2023-10-16" @default.
- W2142325714 title "Induction of interleukin-10 by HIV antigens in peripheral mononuclear cells of health care workers after occupational exposure to HIV-1-positive blood" @default.
- W2142325714 cites W1601365541 @default.
- W2142325714 cites W1974647588 @default.
- W2142325714 cites W2033431358 @default.
- W2142325714 cites W2063011880 @default.
- W2142325714 cites W2071877014 @default.
- W2142325714 cites W2104503802 @default.
- W2142325714 cites W2118110579 @default.
- W2142325714 cites W2170206314 @default.
- W2142325714 cites W2329960468 @default.
- W2142325714 doi "https://doi.org/10.1590/s0100-879x2002000600010" @default.
- W2142325714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12045835" @default.
- W2142325714 hasPublicationYear "2002" @default.
- W2142325714 type Work @default.
- W2142325714 sameAs 2142325714 @default.
- W2142325714 citedByCount "1" @default.
- W2142325714 crossrefType "journal-article" @default.
- W2142325714 hasAuthorship W2142325714A5024588860 @default.
- W2142325714 hasAuthorship W2142325714A5025542473 @default.
- W2142325714 hasAuthorship W2142325714A5030844937 @default.
- W2142325714 hasAuthorship W2142325714A5044529313 @default.
- W2142325714 hasAuthorship W2142325714A5079261852 @default.
- W2142325714 hasAuthorship W2142325714A5079615499 @default.
- W2142325714 hasBestOaLocation W21423257141 @default.
- W2142325714 hasConcept C137061746 @default.
- W2142325714 hasConcept C147483822 @default.
- W2142325714 hasConcept C154317977 @default.
- W2142325714 hasConcept C202751555 @default.
- W2142325714 hasConcept C203014093 @default.
- W2142325714 hasConcept C2777451964 @default.
- W2142325714 hasConcept C3013748606 @default.
- W2142325714 hasConcept C55493867 @default.
- W2142325714 hasConcept C71924100 @default.
- W2142325714 hasConcept C86803240 @default.
- W2142325714 hasConcept C8891405 @default.
- W2142325714 hasConceptScore W2142325714C137061746 @default.
- W2142325714 hasConceptScore W2142325714C147483822 @default.
- W2142325714 hasConceptScore W2142325714C154317977 @default.
- W2142325714 hasConceptScore W2142325714C202751555 @default.
- W2142325714 hasConceptScore W2142325714C203014093 @default.
- W2142325714 hasConceptScore W2142325714C2777451964 @default.
- W2142325714 hasConceptScore W2142325714C3013748606 @default.
- W2142325714 hasConceptScore W2142325714C55493867 @default.
- W2142325714 hasConceptScore W2142325714C71924100 @default.
- W2142325714 hasConceptScore W2142325714C86803240 @default.
- W2142325714 hasConceptScore W2142325714C8891405 @default.
- W2142325714 hasIssue "6" @default.
- W2142325714 hasLocation W21423257141 @default.
- W2142325714 hasLocation W21423257142 @default.
- W2142325714 hasLocation W21423257143 @default.
- W2142325714 hasOpenAccess W2142325714 @default.
- W2142325714 hasPrimaryLocation W21423257141 @default.
- W2142325714 hasRelatedWork W2001055320 @default.
- W2142325714 hasRelatedWork W2008949385 @default.
- W2142325714 hasRelatedWork W2031356189 @default.
- W2142325714 hasRelatedWork W2043505088 @default.
- W2142325714 hasRelatedWork W2220102944 @default.
- W2142325714 hasRelatedWork W2381196212 @default.
- W2142325714 hasRelatedWork W2409441623 @default.
- W2142325714 hasRelatedWork W26323743 @default.
- W2142325714 hasRelatedWork W4290205309 @default.
- W2142325714 hasRelatedWork W1988261318 @default.
- W2142325714 hasVolume "35" @default.
- W2142325714 isParatext "false" @default.
- W2142325714 isRetracted "false" @default.
- W2142325714 magId "2142325714" @default.
- W2142325714 workType "article" @default.