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• W2142343268 abstract "A series of androstano[17,16-c]pyrazolines and their oxidized derivatives (2–14) were synthesized using 3β-hydroxyandrostan-17-one as a starting material (1a, b). The synthesized compounds were evaluated for their antiandrogenic activity compared to that of Cyproterone® as positive control. Some of the compounds exhibited better antiandrogenic activity than the reference drug. The detailed synthesis, spectroscopic data, ED50, and toxicity (LD50 and LD90) of the synthesized compounds were reported." @default.
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• W2142343268 date "2006-01-01" @default.
• W2142343268 modified "2023-09-23" @default.
• W2142343268 title "Synthesis and antiandrogenic activity of some new 3-substituted androstano[17,16-c]-5′-aryl-pyrazoline and their derivatives" @default.
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• W2142343268 doi "https://doi.org/10.1016/j.bmc.2005.08.024" @default.
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