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- W2142386606 abstract "L-5HTP and tranylcypromine were compared in an open, but controlled and cross-over study, in patients suffering from major depression; all were non-responders to several reuptake inhibitors, including oxaprotiline and fluvoxamine. After four unsuccessful sleep-deprivations, L-5HTP or tranylcypromine were given during four weeks in a crossover design. Of 17 patients given L-5HTP during both treatment periods, none responded, whereas of 26 patients treated with tranylcypromine, 15 responded. Thus, L-5HTP is not a therapeutically effective alternative in depressed patients who have not responded to reuptake inhibitors." @default.
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- W2142386606 date "1985-07-01" @default.
- W2142386606 modified "2023-09-27" @default.
- W2142386606 title "L-5HTP in Depression Resistant to Re-Uptake Inhibitors" @default.
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- W2142386606 doi "https://doi.org/10.1192/bjp.147.1.16" @default.
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