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- W2142387178 abstract "Colorectal cancer (CRC) is the third most common cause of cancer-related death in the United States. Early identification and treatment of pre-cancerous colorectal lesions, or node-negative CRC are highly effective interventions that substantially reduce disease-specific mortality. Colonoscopy remains a highly effective primary screening tool based on its excellent diagnostic accuracy, and its ability to remove pre-cancerous lesions. However, the nature of the procedure limits compliance with colonoscopy intended for population-based CRC screening. A significant advance in the screening and care of these patients could be realized by blood-based biomarkers, which could accurately identify patients at-risk for CRC development whom might benefit from early and/or more frequent surveillance for disease. We reviewed and herein discuss the potential for serum based DNA methylation biomarkers for screening and early detection of CRC." @default.
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- W2142387178 date "2013-01-01" @default.
- W2142387178 modified "2023-10-13" @default.
- W2142387178 title "Serum-Based DNA Methylation Biomarkers in Colorectal Cancer: Potential for Screening and Early Detection" @default.
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- W2142387178 doi "https://doi.org/10.7150/jca.5839" @default.
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