FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2142450653> ?p ?o ?g. }

• W2142450653 endingPage "2751" @default.
• W2142450653 startingPage "2742" @default.
• W2142450653 abstract "Lymphocytes use integrin-based platforms to move and adhere firmly to the surface of other cells. The molecular mechanisms governing lymphocyte adhesion dynamics are however poorly understood. In this study, we show that in mouse B lymphocytes, the actin binding protein vinculin localizes to the ring-shaped integrin-rich domain of the immune synapse (IS); the assembly of this platform, triggered by cognate immune interactions, is needed for chemokine-mediated B cell motility arrest and leads to firm, long-lasting B cell adhesion to the APC. Vinculin is recruited early in IS formation, in parallel to a local phosphatidylinositol (4,5)-bisphosphate wave, and requires spleen tyrosine kinase activity. Lack of vinculin at the IS impairs firm adhesion, promoting, in turn, cell migration with Ag clustered at the uropod. Vinculin localization to the B cell contact area depends on actomyosin. These results identify vinculin as a major controller of integrin-mediated adhesion dynamics in B cells." @default.
• W2142450653 created "2016-06-24" @default.
• W2142450653 creator A5044151726 @default.
• W2142450653 creator A5059535145 @default.
• W2142450653 creator A5061724902 @default.
• W2142450653 date "2013-09-01" @default.
• W2142450653 modified "2023-10-13" @default.
• W2142450653 title "Vinculin Arrests Motile B Cells by Stabilizing Integrin Clustering at the Immune Synapse" @default.
• W2142450653 cites W1495361973 @default.
• W2142450653 cites W1525030838 @default.
• W2142450653 cites W1967139887 @default.
• W2142450653 cites W1968272833 @default.
• W2142450653 cites W1970248850 @default.
• W2142450653 cites W1973201987 @default.
• W2142450653 cites W1974374103 @default.
• W2142450653 cites W1982022868 @default.
• W2142450653 cites W1987625947 @default.
• W2142450653 cites W1991214264 @default.
• W2142450653 cites W2006519535 @default.
• W2142450653 cites W2011562061 @default.
• W2142450653 cites W2014118715 @default.
• W2142450653 cites W2023841575 @default.
• W2142450653 cites W2026463319 @default.
• W2142450653 cites W2027298203 @default.
• W2142450653 cites W2027381548 @default.
• W2142450653 cites W2028682200 @default.
• W2142450653 cites W2035325286 @default.
• W2142450653 cites W2036286128 @default.
• W2142450653 cites W2048305477 @default.
• W2142450653 cites W2049398130 @default.
• W2142450653 cites W2056703680 @default.
• W2142450653 cites W2059532010 @default.
• W2142450653 cites W2070495940 @default.
• W2142450653 cites W2078849072 @default.
• W2142450653 cites W2083735008 @default.
• W2142450653 cites W2084302112 @default.
• W2142450653 cites W2086149271 @default.
• W2142450653 cites W2094577052 @default.
• W2142450653 cites W2097139362 @default.
• W2142450653 cites W2097555314 @default.
• W2142450653 cites W2102551110 @default.
• W2142450653 cites W2109137926 @default.
• W2142450653 cites W2109706035 @default.
• W2142450653 cites W2115759372 @default.
• W2142450653 cites W2123216897 @default.
• W2142450653 cites W2125292721 @default.
• W2142450653 cites W2125744499 @default.
• W2142450653 cites W2134873228 @default.
• W2142450653 cites W2139970775 @default.
• W2142450653 cites W2142371485 @default.
• W2142450653 cites W2143805521 @default.
• W2142450653 cites W2145258545 @default.
• W2142450653 cites W2145392559 @default.
• W2142450653 cites W2149873896 @default.
• W2142450653 cites W2149928606 @default.
• W2142450653 cites W2155942922 @default.
• W2142450653 cites W2158491428 @default.
• W2142450653 cites W2162560056 @default.
• W2142450653 cites W2167552306 @default.
• W2142450653 cites W2169006700 @default.
• W2142450653 cites W2169007182 @default.
• W2142450653 cites W2171644620 @default.
• W2142450653 cites W2185271266 @default.
• W2142450653 doi "https://doi.org/10.4049/jimmunol.1300684" @default.
• W2142450653 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23872053" @default.
• W2142450653 hasPublicationYear "2013" @default.
• W2142450653 type Work @default.
• W2142450653 sameAs 2142450653 @default.
• W2142450653 citedByCount "20" @default.
• W2142450653 countsByYear W21424506532014 @default.
• W2142450653 countsByYear W21424506532015 @default.
• W2142450653 countsByYear W21424506532016 @default.
• W2142450653 countsByYear W21424506532018 @default.
• W2142450653 countsByYear W21424506532019 @default.
• W2142450653 countsByYear W21424506532020 @default.
• W2142450653 countsByYear W21424506532021 @default.
• W2142450653 countsByYear W21424506532023 @default.
• W2142450653 crossrefType "journal-article" @default.
• W2142450653 hasAuthorship W2142450653A5044151726 @default.
• W2142450653 hasAuthorship W2142450653A5059535145 @default.
• W2142450653 hasAuthorship W2142450653A5061724902 @default.
• W2142450653 hasBestOaLocation W21424506531 @default.
• W2142450653 hasConcept C125705527 @default.
• W2142450653 hasConcept C1491633281 @default.
• W2142450653 hasConcept C151166631 @default.
• W2142450653 hasConcept C178790620 @default.
• W2142450653 hasConcept C185592680 @default.
• W2142450653 hasConcept C19317047 @default.
• W2142450653 hasConcept C195687474 @default.
• W2142450653 hasConcept C203014093 @default.
• W2142450653 hasConcept C2776090121 @default.
• W2142450653 hasConcept C2777979848 @default.
• W2142450653 hasConcept C55493867 @default.
• W2142450653 hasConcept C62478195 @default.
• W2142450653 hasConcept C84416704 @default.
• W2142450653 hasConcept C85789140 @default.
• W2142450653 hasConcept C86803240 @default.
• W2142450653 hasConcept C8891405 @default.

• next