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• W2142728218 abstract "Neuroendocrine cell hyperplasia of infancy (NEHI) has recently been described as an obstructive airway disease that affects infants aged 1–24 months, and presents typically with tachypnoea, crackles and hypoxia. The pathogenesis of the disease is unknown. We describe the clinical course of nine infants with radiologically and histologically confirmed NEHI. Host or environmental factors were not associated with the disease development. All infants with lung function tests demonstrated findings consistent with severe irreversible peripheral airway obstruction, assessed with whole body plethysmography (6/6) or the rapid thoracoabdominal compression technique (5/5). While the symptoms abated in all infants, six infants developed a non-atopic asthma during the follow-up. Systemic or inhaled corticosteroid treatment did not affect the duration of the symptoms. NEHI may mimic severe asthma and thus this entity should be taken into account when evaluating infants with chronic respiratory symptoms." @default.
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• W2142728218 date "2012-11-17" @default.
• W2142728218 modified "2023-10-01" @default.
• W2142728218 title "Neuroendocrine cell hyperplasia of infancy: a prospective follow-up of nine children" @default.
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• W2142728218 doi "https://doi.org/10.1136/archdischild-2012-302115" @default.
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