FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2142749013> ?p ?o ?g. }

• W2142749013 endingPage "1015" @default.
• W2142749013 startingPage "1007" @default.
• W2142749013 abstract "The possible relationship between calcium and microtubules in the regulation of granulosa cell steroidogenesis was assessed by using agents known to alter microtubule-tubulin equilibrium together with the ionophore A23187, an antibiotic that facilitates the movement of calcium across plasma membranes. Using immunofluorescence and morphometric analysis, we determined alterations in microtubule organization and overall cell shape, respectively, in response to ionophore-stimulated production of progesterone and 20 alpha-hydroxypregn-4-en-3-one (20 alpha-OH-progesterone) during 24 h of culture. In addition, the influences of colchicine and nocodazole, two agents known to induce microtubule depolymerization, and of taxol, an agent that stabilizes tubulin polymers, on calcium-dependent regulation of granulosa cell progestin production in vitro were examined. Cells cultured as controls were flattened, highly irregular in outline, and associated with a complexly organized, well-spread cytoplasmic network of microtubules. In contrast, those maintained in the presence of increasing concentrations of ionophore were progressively more circular and smooth in outline, occupied less area on the growth surface, and contained cytoplasmic arrays of microtubules considerably less extensive than those of the controls and occupying areas defined by the more regular cellular perimeters. While progestin production in the absence or presence of a submaximally stimulatory concentration of A23187 was increased by both colchicine and nocodazole, the microtubule-depolymerizing agents had little to no effect on the production of the steroids by granulosa cells maximally stimulated by the ionophore. However, both basal and ionophore-induced progestin production were unaltered by taxol except at a concentration of 10 microM in the presence of 0.25 micrograms/ml A23187.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2142749013 created "2016-06-24" @default.
• W2142749013 creator A5013170437 @default.
• W2142749013 creator A5088468059 @default.
• W2142749013 date "1987-05-01" @default.
• W2142749013 modified "2023-09-24" @default.
• W2142749013 title "Microtubules and the Calcium-Dependent Regulation of Rat Granulosa Cell Steroidogenesis1" @default.
• W2142749013 cites W1500700435 @default.
• W2142749013 cites W1520787125 @default.
• W2142749013 cites W1906431592 @default.
• W2142749013 cites W1964769283 @default.
• W2142749013 cites W1971501979 @default.
• W2142749013 cites W1976580430 @default.
• W2142749013 cites W1981477956 @default.
• W2142749013 cites W1985079309 @default.
• W2142749013 cites W1995035941 @default.
• W2142749013 cites W2001006416 @default.
• W2142749013 cites W2008190738 @default.
• W2142749013 cites W2016520189 @default.
• W2142749013 cites W2020282014 @default.
• W2142749013 cites W2030004024 @default.
• W2142749013 cites W2032766957 @default.
• W2142749013 cites W2032786029 @default.
• W2142749013 cites W2040151760 @default.
• W2142749013 cites W2041300637 @default.
• W2142749013 cites W2046007185 @default.
• W2142749013 cites W2046303194 @default.
• W2142749013 cites W2090070255 @default.
• W2142749013 cites W2136723220 @default.
• W2142749013 cites W2137756635 @default.
• W2142749013 cites W2145555831 @default.
• W2142749013 cites W2189012402 @default.
• W2142749013 cites W2275570665 @default.
• W2142749013 cites W2335448436 @default.
• W2142749013 cites W2406016146 @default.
• W2142749013 cites W2411339929 @default.
• W2142749013 cites W2466880197 @default.
• W2142749013 doi "https://doi.org/10.1095/biolreprod36.4.1007" @default.
• W2142749013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3109509" @default.
• W2142749013 hasPublicationYear "1987" @default.
• W2142749013 type Work @default.
• W2142749013 sameAs 2142749013 @default.
• W2142749013 citedByCount "16" @default.
• W2142749013 countsByYear W21427490132012 @default.
• W2142749013 countsByYear W21427490132021 @default.
• W2142749013 crossrefType "journal-article" @default.
• W2142749013 hasAuthorship W2142749013A5013170437 @default.
• W2142749013 hasAuthorship W2142749013A5088468059 @default.
• W2142749013 hasBestOaLocation W21427490131 @default.
• W2142749013 hasConcept C126322002 @default.
• W2142749013 hasConcept C134018914 @default.
• W2142749013 hasConcept C142669718 @default.
• W2142749013 hasConcept C1491633281 @default.
• W2142749013 hasConcept C190062978 @default.
• W2142749013 hasConcept C20418707 @default.
• W2142749013 hasConcept C2776636253 @default.
• W2142749013 hasConcept C2776989580 @default.
• W2142749013 hasConcept C2779014961 @default.
• W2142749013 hasConcept C2779363559 @default.
• W2142749013 hasConcept C41625074 @default.
• W2142749013 hasConcept C519063684 @default.
• W2142749013 hasConcept C54355233 @default.
• W2142749013 hasConcept C55493867 @default.
• W2142749013 hasConcept C71924100 @default.
• W2142749013 hasConcept C79879829 @default.
• W2142749013 hasConcept C84425145 @default.
• W2142749013 hasConcept C86803240 @default.
• W2142749013 hasConcept C95444343 @default.
• W2142749013 hasConceptScore W2142749013C126322002 @default.
• W2142749013 hasConceptScore W2142749013C134018914 @default.
• W2142749013 hasConceptScore W2142749013C142669718 @default.
• W2142749013 hasConceptScore W2142749013C1491633281 @default.
• W2142749013 hasConceptScore W2142749013C190062978 @default.
• W2142749013 hasConceptScore W2142749013C20418707 @default.
• W2142749013 hasConceptScore W2142749013C2776636253 @default.
• W2142749013 hasConceptScore W2142749013C2776989580 @default.
• W2142749013 hasConceptScore W2142749013C2779014961 @default.
• W2142749013 hasConceptScore W2142749013C2779363559 @default.
• W2142749013 hasConceptScore W2142749013C41625074 @default.
• W2142749013 hasConceptScore W2142749013C519063684 @default.
• W2142749013 hasConceptScore W2142749013C54355233 @default.
• W2142749013 hasConceptScore W2142749013C55493867 @default.
• W2142749013 hasConceptScore W2142749013C71924100 @default.
• W2142749013 hasConceptScore W2142749013C79879829 @default.
• W2142749013 hasConceptScore W2142749013C84425145 @default.
• W2142749013 hasConceptScore W2142749013C86803240 @default.
• W2142749013 hasConceptScore W2142749013C95444343 @default.
• W2142749013 hasIssue "4" @default.
• W2142749013 hasLocation W21427490131 @default.
• W2142749013 hasLocation W21427490132 @default.
• W2142749013 hasOpenAccess W2142749013 @default.
• W2142749013 hasPrimaryLocation W21427490131 @default.
• W2142749013 hasRelatedWork W1972671198 @default.
• W2142749013 hasRelatedWork W2017365073 @default.
• W2142749013 hasRelatedWork W2068188645 @default.
• W2142749013 hasRelatedWork W2069851853 @default.
• W2142749013 hasRelatedWork W2085397809 @default.
• W2142749013 hasRelatedWork W2142749013 @default.

• next