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- W2142822969 endingPage "275" @default.
- W2142822969 startingPage "265" @default.
- W2142822969 abstract "The current regulation of parathyroid hormone (PTH) and the development of parathyroid disorders in chronic kidney disease involve complex mechanisms. Factors such as calcium, phosphorous, calcitriol, vitamin D receptor, calcium-sensing receptor and fibroblast growth factor 23 play a key role in the regulatory process in the pathogenesis of secondary hyperparathyroidism.This review provides an analysis of published results related to the different models and approaches used to study the mechanisms involved in the pathogenesis of secondary hyperparathyroidism. The review includes clinical studies, animal and ex vivo/in vitro models which have been extensively used in this area.Readers will have an overview of the main findings and progress achieved in the knowledge of the parathyroid function combining the results obtained from the different models used to understand the parathyroid gland regulation.Each of the available models used to study the complex system of parathyroid regulation has advantages and limitations; therefore, it is necessary to combine the information obtained from more than one model in order to have a more complete knowledge of the mechanisms involved in PTH regulation." @default.
- W2142822969 created "2016-06-24" @default.
- W2142822969 creator A5043363248 @default.
- W2142822969 creator A5052450362 @default.
- W2142822969 creator A5057833421 @default.
- W2142822969 creator A5066920068 @default.
- W2142822969 date "2010-02-13" @default.
- W2142822969 modified "2023-09-27" @default.
- W2142822969 title "Parathyroid gland regulation: contribution of thein vivoandin vitromodels" @default.
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