Matches in SemOpenAlex for { <https://semopenalex.org/work/W2142872564> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2142872564 abstract "The quest for the development of an ideal male contraceptive has led to the discovery of the antifertility property of some species of C. papaya seed extracts. This study investigates the antifertility activity and reversibility of ethanol extract of C. papaya seeds in sexually matured male Wistar rats. 30 adult males and 60 female Wistar rats weighing between 180 and 220 g were used for the study. The male rats were randomly divided into 3 groups of 10 each. Group I which served as control were orally administered distilled water while groups II and III received 100 and 250 mg/kg/day of ethanol extract of C. papaya seeds respectively for a period of 90 days. 5 males from each group were subjected to fertility test before they were sacrificed to harvest the testes for histopathological analysis. The administration of the extract was discontinued for another 90 days period and the remaining 5 males in each group were subjected to fertility test before they were sacrificed to obtain the testes for histopathological analysis. The results showed normal pregnancy outcome in the females paired with the control group, reduced and zero pregnancy outcome in the females paired with the 100 and 250 mg/kg groups respectively after 90-day administration of the extract. After 90 days of discontinued administration of extract, normal pregnancy outcome were recorded in both the control and treated groups. The result of the histopathological analysis showed a moderate and highly depleted germinal epithelium in the 100 and 250 mg/kg groups respectively after 90 day administration of the extract. The germinal epithelium seen in both the control and the experimental groups were normal after 90 days discontinued extract administration. The study concludes that ethanol extract of C. papaya seeds induces reversible male contraception in Wistar rats." @default.
- W2142872564 created "2016-06-24" @default.
- W2142872564 creator A5009382671 @default.
- W2142872564 creator A5014940474 @default.
- W2142872564 creator A5017710516 @default.
- W2142872564 creator A5038280671 @default.
- W2142872564 creator A5067096838 @default.
- W2142872564 creator A5076035976 @default.
- W2142872564 creator A5077981426 @default.
- W2142872564 date "2011-01-01" @default.
- W2142872564 modified "2023-09-23" @default.
- W2142872564 title "Ethanol Extract of Carica papaya Seeds Induces Reversible Contraception in Adult Male Wistar Rats" @default.
- W2142872564 cites W1583691919 @default.
- W2142872564 cites W1964456676 @default.
- W2142872564 cites W2015491212 @default.
- W2142872564 cites W2019611354 @default.
- W2142872564 cites W2067525656 @default.
- W2142872564 cites W2082356362 @default.
- W2142872564 cites W2092606025 @default.
- W2142872564 cites W2265147515 @default.
- W2142872564 cites W2396019583 @default.
- W2142872564 cites W2418486829 @default.
- W2142872564 cites W2425311941 @default.
- W2142872564 cites W2467524863 @default.
- W2142872564 hasPublicationYear "2011" @default.
- W2142872564 type Work @default.
- W2142872564 sameAs 2142872564 @default.
- W2142872564 citedByCount "2" @default.
- W2142872564 countsByYear W21428725642014 @default.
- W2142872564 countsByYear W21428725642015 @default.
- W2142872564 crossrefType "journal-article" @default.
- W2142872564 hasAuthorship W2142872564A5009382671 @default.
- W2142872564 hasAuthorship W2142872564A5014940474 @default.
- W2142872564 hasAuthorship W2142872564A5017710516 @default.
- W2142872564 hasAuthorship W2142872564A5038280671 @default.
- W2142872564 hasAuthorship W2142872564A5067096838 @default.
- W2142872564 hasAuthorship W2142872564A5076035976 @default.
- W2142872564 hasAuthorship W2142872564A5077981426 @default.
- W2142872564 hasConcept C2779231358 @default.
- W2142872564 hasConcept C2779234561 @default.
- W2142872564 hasConcept C2908647359 @default.
- W2142872564 hasConcept C42407357 @default.
- W2142872564 hasConcept C518429986 @default.
- W2142872564 hasConcept C54355233 @default.
- W2142872564 hasConcept C556039675 @default.
- W2142872564 hasConcept C59822182 @default.
- W2142872564 hasConcept C71924100 @default.
- W2142872564 hasConcept C86803240 @default.
- W2142872564 hasConcept C99454951 @default.
- W2142872564 hasConceptScore W2142872564C2779231358 @default.
- W2142872564 hasConceptScore W2142872564C2779234561 @default.
- W2142872564 hasConceptScore W2142872564C2908647359 @default.
- W2142872564 hasConceptScore W2142872564C42407357 @default.
- W2142872564 hasConceptScore W2142872564C518429986 @default.
- W2142872564 hasConceptScore W2142872564C54355233 @default.
- W2142872564 hasConceptScore W2142872564C556039675 @default.
- W2142872564 hasConceptScore W2142872564C59822182 @default.
- W2142872564 hasConceptScore W2142872564C71924100 @default.
- W2142872564 hasConceptScore W2142872564C86803240 @default.
- W2142872564 hasConceptScore W2142872564C99454951 @default.
- W2142872564 hasLocation W21428725641 @default.
- W2142872564 hasOpenAccess W2142872564 @default.
- W2142872564 hasPrimaryLocation W21428725641 @default.
- W2142872564 hasRelatedWork W2074549457 @default.
- W2142872564 hasRelatedWork W2116768642 @default.
- W2142872564 hasRelatedWork W2184266514 @default.
- W2142872564 hasRelatedWork W2186974993 @default.
- W2142872564 hasRelatedWork W2187185696 @default.
- W2142872564 hasRelatedWork W2253679805 @default.
- W2142872564 hasRelatedWork W2326321421 @default.
- W2142872564 hasRelatedWork W2388475821 @default.
- W2142872564 hasRelatedWork W2393129046 @default.
- W2142872564 hasRelatedWork W2902191598 @default.
- W2142872564 hasRelatedWork W2948378903 @default.
- W2142872564 hasRelatedWork W2967776837 @default.
- W2142872564 hasRelatedWork W2995203193 @default.
- W2142872564 hasRelatedWork W3028603892 @default.
- W2142872564 hasRelatedWork W424901859 @default.
- W2142872564 hasRelatedWork W82304335 @default.
- W2142872564 hasRelatedWork W2186019531 @default.
- W2142872564 hasRelatedWork W2189228057 @default.
- W2142872564 hasRelatedWork W2571209588 @default.
- W2142872564 hasRelatedWork W2785491303 @default.
- W2142872564 isParatext "false" @default.
- W2142872564 isRetracted "false" @default.
- W2142872564 magId "2142872564" @default.
- W2142872564 workType "article" @default.