FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2142954279> ?p ?o ?g. }

• W2142954279 endingPage "1587" @default.
• W2142954279 startingPage "1581" @default.
• W2142954279 abstract "The kidney’s responsiveness to male sexual hormones has been often neglected. Renal secretion of organic anions is higher in male than in female individuals; as a consequence, most of the xenobiotics that are excreted from the organism through this pathway are eliminated more rapidly by males than by female animals. To gain further insight into this issue, we studied in vitro and in vivo characteristics of the transport of p-aminohippurate (PAH), a suitable marker for this system, in male and female rats, under different hormonal conditions. Kinetics of PAH showed a shorter elimination half-time in male than in female rats (t1/2el: male = 16.2 ± 2.1 min, female= 25.7 ± 4.5 min, P < 0.05). Castration of male rats increased t1/2el to a value similar to that of female rats (t1/2el: orchiectomized rat = 28.1 ± 7.1 min). Testosterone treatment of female rats increased the elimination rate to a value similar to that of male rats. In vitro PAH uptake by renal cortical slices from intact male rats was higher than that by slices from orchiectomized rats. Kinetic analyses of PAH uptake suggest that the difference was caused by a lower number of transporting molecules in orchiectomized than in intact animals, whereas the transporting capacity for each carrier was similar in male and in orchiectomized rats. Our results suggest that testosterone increases the number of functional carriers for PAH in the kidney." @default.
• W2142954279 created "2016-06-24" @default.
• W2142954279 creator A5033974697 @default.
• W2142954279 creator A5059048688 @default.
• W2142954279 creator A5066855720 @default.
• W2142954279 creator A5067668502 @default.
• W2142954279 date "1998-04-01" @default.
• W2142954279 modified "2023-10-17" @default.
• W2142954279 title "Influence of Sex Differences on the Renal Secretion of Organic Anions" @default.
• W2142954279 cites W1537077061 @default.
• W2142954279 cites W1975007646 @default.
• W2142954279 cites W1976680833 @default.
• W2142954279 cites W2000929308 @default.
• W2142954279 cites W2003905409 @default.
• W2142954279 cites W2020282477 @default.
• W2142954279 cites W2026057063 @default.
• W2142954279 cites W2040894635 @default.
• W2142954279 cites W2045125575 @default.
• W2142954279 cites W2045185915 @default.
• W2142954279 cites W2049743237 @default.
• W2142954279 cites W2064911183 @default.
• W2142954279 cites W2072093908 @default.
• W2142954279 cites W2074215115 @default.
• W2142954279 cites W2082230812 @default.
• W2142954279 cites W2087492252 @default.
• W2142954279 cites W2093483032 @default.
• W2142954279 cites W2279179891 @default.
• W2142954279 doi "https://doi.org/10.1210/endo.139.4.5930" @default.
• W2142954279 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9528937" @default.
• W2142954279 hasPublicationYear "1998" @default.
• W2142954279 type Work @default.
• W2142954279 sameAs 2142954279 @default.
• W2142954279 citedByCount "44" @default.
• W2142954279 countsByYear W21429542792012 @default.
• W2142954279 countsByYear W21429542792013 @default.
• W2142954279 countsByYear W21429542792014 @default.
• W2142954279 countsByYear W21429542792015 @default.
• W2142954279 countsByYear W21429542792016 @default.
• W2142954279 countsByYear W21429542792017 @default.
• W2142954279 countsByYear W21429542792019 @default.
• W2142954279 countsByYear W21429542792020 @default.
• W2142954279 countsByYear W21429542792021 @default.
• W2142954279 crossrefType "journal-article" @default.
• W2142954279 hasAuthorship W2142954279A5033974697 @default.
• W2142954279 hasAuthorship W2142954279A5059048688 @default.
• W2142954279 hasAuthorship W2142954279A5066855720 @default.
• W2142954279 hasAuthorship W2142954279A5067668502 @default.
• W2142954279 hasBestOaLocation W21429542791 @default.
• W2142954279 hasConcept C115448650 @default.
• W2142954279 hasConcept C126322002 @default.
• W2142954279 hasConcept C134018914 @default.
• W2142954279 hasConcept C150903083 @default.
• W2142954279 hasConcept C16613235 @default.
• W2142954279 hasConcept C181199279 @default.
• W2142954279 hasConcept C185592680 @default.
• W2142954279 hasConcept C202751555 @default.
• W2142954279 hasConcept C207001950 @default.
• W2142954279 hasConcept C2779256933 @default.
• W2142954279 hasConcept C2779279991 @default.
• W2142954279 hasConcept C2780091579 @default.
• W2142954279 hasConcept C2781440318 @default.
• W2142954279 hasConcept C2992926266 @default.
• W2142954279 hasConcept C49039625 @default.
• W2142954279 hasConcept C55493867 @default.
• W2142954279 hasConcept C71315377 @default.
• W2142954279 hasConcept C71924100 @default.
• W2142954279 hasConcept C86803240 @default.
• W2142954279 hasConceptScore W2142954279C115448650 @default.
• W2142954279 hasConceptScore W2142954279C126322002 @default.
• W2142954279 hasConceptScore W2142954279C134018914 @default.
• W2142954279 hasConceptScore W2142954279C150903083 @default.
• W2142954279 hasConceptScore W2142954279C16613235 @default.
• W2142954279 hasConceptScore W2142954279C181199279 @default.
• W2142954279 hasConceptScore W2142954279C185592680 @default.
• W2142954279 hasConceptScore W2142954279C202751555 @default.
• W2142954279 hasConceptScore W2142954279C207001950 @default.
• W2142954279 hasConceptScore W2142954279C2779256933 @default.
• W2142954279 hasConceptScore W2142954279C2779279991 @default.
• W2142954279 hasConceptScore W2142954279C2780091579 @default.
• W2142954279 hasConceptScore W2142954279C2781440318 @default.
• W2142954279 hasConceptScore W2142954279C2992926266 @default.
• W2142954279 hasConceptScore W2142954279C49039625 @default.
• W2142954279 hasConceptScore W2142954279C55493867 @default.
• W2142954279 hasConceptScore W2142954279C71315377 @default.
• W2142954279 hasConceptScore W2142954279C71924100 @default.
• W2142954279 hasConceptScore W2142954279C86803240 @default.
• W2142954279 hasIssue "4" @default.
• W2142954279 hasLocation W21429542791 @default.
• W2142954279 hasLocation W21429542792 @default.
• W2142954279 hasOpenAccess W2142954279 @default.
• W2142954279 hasPrimaryLocation W21429542791 @default.
• W2142954279 hasRelatedWork W1965833776 @default.
• W2142954279 hasRelatedWork W2027237635 @default.
• W2142954279 hasRelatedWork W2036732116 @default.
• W2142954279 hasRelatedWork W2046915766 @default.
• W2142954279 hasRelatedWork W2076924632 @default.
• W2142954279 hasRelatedWork W2101146068 @default.
• W2142954279 hasRelatedWork W2108619254 @default.

• next