Matches in SemOpenAlex for { <https://semopenalex.org/work/W2142970734> ?p ?o ?g. }
- W2142970734 endingPage "88" @default.
- W2142970734 startingPage "178" @default.
- W2142970734 abstract "Invasive fungal infections (IFIs) have become increasingly prevalent in the recent decade along with the increasing populations of immunocompromised patients and widespread use of the broad-spectrum antibiotics. The morbidity and the mortality of IFIs remain high while the diagnosis and treatment of IFIs are highly challenging. Recent advances in diagnostic methods and antifungal agents provide the potential to improve the outcomes of these infections. Conventional diagnostic methods including microbiological cultures and histopathological diagnosis have the disadvantages of either insensitivity or requiring invasive procedures. The innovative techniques of detecting circulating fungal antigens and detecting fungal genomic DNA represent improvements in the diagnosis of invasive aspergillosis. Several antifungal agents have been developed in recent years, such as lipid formulations of amphotericin B, newer azoles, and echinocandins. These agents have either lower toxicities or greater activities against certain fungi compared with older treatments. With the availability of diverse antifungal agents, their use in combination has the potential to produce additive or synergistic effects, leading to better treatment outcomes. Large-scale randomized clinical trials are needed to confirm the efficacy of combination strategies." @default.
- W2142970734 created "2016-06-24" @default.
- W2142970734 creator A5004807354 @default.
- W2142970734 creator A5028835481 @default.
- W2142970734 creator A5030958767 @default.
- W2142970734 date "2006-06-01" @default.
- W2142970734 modified "2023-09-29" @default.
- W2142970734 title "Invasive fungal infection--laboratory diagnosis and antifungal treatment." @default.
- W2142970734 cites W157973430 @default.
- W2142970734 cites W1863838995 @default.
- W2142970734 cites W1911541991 @default.
- W2142970734 cites W1964791233 @default.
- W2142970734 cites W1965945033 @default.
- W2142970734 cites W1966639183 @default.
- W2142970734 cites W1967601691 @default.
- W2142970734 cites W1969650434 @default.
- W2142970734 cites W1974053625 @default.
- W2142970734 cites W1974241692 @default.
- W2142970734 cites W1974953831 @default.
- W2142970734 cites W1979180336 @default.
- W2142970734 cites W1985985205 @default.
- W2142970734 cites W1987658252 @default.
- W2142970734 cites W1989277463 @default.
- W2142970734 cites W1991020976 @default.
- W2142970734 cites W1992970808 @default.
- W2142970734 cites W2003661565 @default.
- W2142970734 cites W2009224808 @default.
- W2142970734 cites W2016071165 @default.
- W2142970734 cites W2024310762 @default.
- W2142970734 cites W2026729241 @default.
- W2142970734 cites W2027962943 @default.
- W2142970734 cites W2029714817 @default.
- W2142970734 cites W2038485278 @default.
- W2142970734 cites W2040405627 @default.
- W2142970734 cites W2040773127 @default.
- W2142970734 cites W2043706449 @default.
- W2142970734 cites W2052913243 @default.
- W2142970734 cites W2069966646 @default.
- W2142970734 cites W2082695689 @default.
- W2142970734 cites W2084008476 @default.
- W2142970734 cites W2085440534 @default.
- W2142970734 cites W2087548480 @default.
- W2142970734 cites W2090630408 @default.
- W2142970734 cites W2092055508 @default.
- W2142970734 cites W2092448979 @default.
- W2142970734 cites W2093920981 @default.
- W2142970734 cites W2096311762 @default.
- W2142970734 cites W2097394217 @default.
- W2142970734 cites W2098175638 @default.
- W2142970734 cites W2099951777 @default.
- W2142970734 cites W2100032900 @default.
- W2142970734 cites W2102584901 @default.
- W2142970734 cites W2104240895 @default.
- W2142970734 cites W2104445943 @default.
- W2142970734 cites W2105376278 @default.
- W2142970734 cites W2106971281 @default.
- W2142970734 cites W2108285432 @default.
- W2142970734 cites W2108781643 @default.
- W2142970734 cites W2109760545 @default.
- W2142970734 cites W2110702182 @default.
- W2142970734 cites W2112230834 @default.
- W2142970734 cites W2114146849 @default.
- W2142970734 cites W2118315045 @default.
- W2142970734 cites W2119286832 @default.
- W2142970734 cites W2122547328 @default.
- W2142970734 cites W2122708612 @default.
- W2142970734 cites W2123454450 @default.
- W2142970734 cites W2124424991 @default.
- W2142970734 cites W2127508258 @default.
- W2142970734 cites W2128039798 @default.
- W2142970734 cites W2128856844 @default.
- W2142970734 cites W2129128266 @default.
- W2142970734 cites W2129942501 @default.
- W2142970734 cites W2133328722 @default.
- W2142970734 cites W2134872646 @default.
- W2142970734 cites W2138738780 @default.
- W2142970734 cites W2139598390 @default.
- W2142970734 cites W2142281465 @default.
- W2142970734 cites W2143474459 @default.
- W2142970734 cites W2144030592 @default.
- W2142970734 cites W2144495358 @default.
- W2142970734 cites W2146306688 @default.
- W2142970734 cites W2146544297 @default.
- W2142970734 cites W2149546447 @default.
- W2142970734 cites W2150250594 @default.
- W2142970734 cites W2156228013 @default.
- W2142970734 cites W2156924221 @default.
- W2142970734 cites W2158271921 @default.
- W2142970734 cites W2159121924 @default.
- W2142970734 cites W2160128406 @default.
- W2142970734 cites W2165739387 @default.
- W2142970734 cites W2170381561 @default.
- W2142970734 cites W2264291980 @default.
- W2142970734 cites W2338427714 @default.
- W2142970734 cites W2339779592 @default.
- W2142970734 cites W24105924 @default.
- W2142970734 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16783447" @default.
- W2142970734 hasPublicationYear "2006" @default.