Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143000346> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2143000346 endingPage "66" @default.
- W2143000346 startingPage "62" @default.
- W2143000346 abstract "Ubiquitin is a 76 amino acid protein with a remarkable degree of evolutionary conservation. Ubiquitin plays an essential role in a large number of eukaryotic cellular processes by targeting proteins for proteasome-mediated degradation. Most ubiquitin genes are found as head-to-tail polymers whose products are posttranslationally processed to ubiquitin monomers. We have characterized polyubuiquitin genes from the photosynthetic amoeboflagellate Chlorarachnion sp. CCMP 621 (also known as Bigelowiella natans) and found that they deviate from the canonical polyubiquitin structure in having an amino acid insertion at the junction between each monomer, suggesting that polyubiquitin processing in this organism is unique among eukaryotes. The gene structure indicates that processing likely cleaves monomers at the amino terminus of the insertion. We examined the phylogenetic distribution of the insertion by sequencing polyubiquitin genes from several other eukaryotic groups and found it to be confined to Cercozoa (including Chlorarachnion, Lotharella, Cercomonas, and Euglypha) and Foraminifera (including Reticulomyxa and Haynesina). This character strongly suggests that Cercozoa and Foraminifera are close relatives and form a new “supergroup” of eukaryotes." @default.
- W2143000346 created "2016-06-24" @default.
- W2143000346 creator A5000089566 @default.
- W2143000346 creator A5018194803 @default.
- W2143000346 creator A5030023294 @default.
- W2143000346 creator A5060816259 @default.
- W2143000346 date "2003-01-01" @default.
- W2143000346 modified "2023-09-30" @default.
- W2143000346 title "A Novel Polyubiquitin Structure in Cercozoa and Foraminifera: Evidence for a New Eukaryotic Supergroup" @default.
- W2143000346 cites W1221688681 @default.
- W2143000346 cites W1507367785 @default.
- W2143000346 cites W1579785391 @default.
- W2143000346 cites W1832030339 @default.
- W2143000346 cites W1969921248 @default.
- W2143000346 cites W1981113277 @default.
- W2143000346 cites W1991930087 @default.
- W2143000346 cites W1994583059 @default.
- W2143000346 cites W1995734176 @default.
- W2143000346 cites W2013745066 @default.
- W2143000346 cites W2040438092 @default.
- W2143000346 cites W2044655424 @default.
- W2143000346 cites W2055321471 @default.
- W2143000346 cites W2069923353 @default.
- W2143000346 cites W2095918749 @default.
- W2143000346 cites W2103986453 @default.
- W2143000346 cites W2105827326 @default.
- W2143000346 cites W2126487146 @default.
- W2143000346 cites W2143903605 @default.
- W2143000346 cites W2166987747 @default.
- W2143000346 cites W2168817846 @default.
- W2143000346 cites W2172692604 @default.
- W2143000346 doi "https://doi.org/10.1093/molbev/msg006" @default.
- W2143000346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12519907" @default.
- W2143000346 hasPublicationYear "2003" @default.
- W2143000346 type Work @default.
- W2143000346 sameAs 2143000346 @default.
- W2143000346 citedByCount "84" @default.
- W2143000346 countsByYear W21430003462012 @default.
- W2143000346 countsByYear W21430003462013 @default.
- W2143000346 countsByYear W21430003462014 @default.
- W2143000346 countsByYear W21430003462016 @default.
- W2143000346 countsByYear W21430003462017 @default.
- W2143000346 countsByYear W21430003462018 @default.
- W2143000346 countsByYear W21430003462019 @default.
- W2143000346 countsByYear W21430003462021 @default.
- W2143000346 countsByYear W21430003462023 @default.
- W2143000346 crossrefType "journal-article" @default.
- W2143000346 hasAuthorship W2143000346A5000089566 @default.
- W2143000346 hasAuthorship W2143000346A5018194803 @default.
- W2143000346 hasAuthorship W2143000346A5030023294 @default.
- W2143000346 hasAuthorship W2143000346A5060816259 @default.
- W2143000346 hasBestOaLocation W21430003461 @default.
- W2143000346 hasConcept C104317684 @default.
- W2143000346 hasConcept C134459356 @default.
- W2143000346 hasConcept C193252679 @default.
- W2143000346 hasConcept C25602115 @default.
- W2143000346 hasConcept C27740335 @default.
- W2143000346 hasConcept C38062823 @default.
- W2143000346 hasConcept C515207424 @default.
- W2143000346 hasConcept C54355233 @default.
- W2143000346 hasConcept C67705224 @default.
- W2143000346 hasConcept C86803240 @default.
- W2143000346 hasConcept C88478588 @default.
- W2143000346 hasConcept C90132467 @default.
- W2143000346 hasConcept C95444343 @default.
- W2143000346 hasConceptScore W2143000346C104317684 @default.
- W2143000346 hasConceptScore W2143000346C134459356 @default.
- W2143000346 hasConceptScore W2143000346C193252679 @default.
- W2143000346 hasConceptScore W2143000346C25602115 @default.
- W2143000346 hasConceptScore W2143000346C27740335 @default.
- W2143000346 hasConceptScore W2143000346C38062823 @default.
- W2143000346 hasConceptScore W2143000346C515207424 @default.
- W2143000346 hasConceptScore W2143000346C54355233 @default.
- W2143000346 hasConceptScore W2143000346C67705224 @default.
- W2143000346 hasConceptScore W2143000346C86803240 @default.
- W2143000346 hasConceptScore W2143000346C88478588 @default.
- W2143000346 hasConceptScore W2143000346C90132467 @default.
- W2143000346 hasConceptScore W2143000346C95444343 @default.
- W2143000346 hasIssue "1" @default.
- W2143000346 hasLocation W21430003461 @default.
- W2143000346 hasLocation W21430003462 @default.
- W2143000346 hasOpenAccess W2143000346 @default.
- W2143000346 hasPrimaryLocation W21430003461 @default.
- W2143000346 hasRelatedWork W2002129075 @default.
- W2143000346 hasRelatedWork W2005485591 @default.
- W2143000346 hasRelatedWork W2059620027 @default.
- W2143000346 hasRelatedWork W2125317050 @default.
- W2143000346 hasRelatedWork W2139653729 @default.
- W2143000346 hasRelatedWork W2348681936 @default.
- W2143000346 hasRelatedWork W4246627024 @default.
- W2143000346 hasRelatedWork W4309654402 @default.
- W2143000346 hasRelatedWork W4378834194 @default.
- W2143000346 hasRelatedWork W4384651976 @default.
- W2143000346 hasVolume "20" @default.
- W2143000346 isParatext "false" @default.
- W2143000346 isRetracted "false" @default.
- W2143000346 magId "2143000346" @default.
- W2143000346 workType "article" @default.