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• W2143005000 abstract "Objective: Our goal was to compare sensitivity, specificity, and predictive values of glucose and cytokines [interleukin-1 (IL-1), interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor (TNF)] in amniotic fluid (AF) to detect an AF-positive culture. Methods: Amniocentesis was performed on 113 patients with preterm labour (PTL) and intact membranes. Fluid was cultured for aerobic and anaerobic bacteria, and for mycoplasmas. AF analysis included cytokines and glucose determinations. Results: The prevalence of positive AF cultures was 11.5% (13/113). Anaerobic bacteria were isolated in 9 patients (69.2%). The glucose <16 mg/dl and cytokines values; IL-1 >640 pg/ml, IL-6 >55,000 pg/ml, IL-8 >1,000 pg/ml, TNF >672 pg/ml, were significantly correlated (P < 0.01) with AF culture result. Glucose had a sensitivity of 69.2% and a specifity of 96% for the prediction of positive AF culture. The sensitivity and specifity of the cytokines ranged from 61.5–53.4% and 79.8–8.99%, respectively. Conclusions: In the diagnosis of the AF-positive culture, glucose <16 mg/dl is more sensitive than cytokines. J. Matern.-Fetal Med. 1999;8:155–158. © 1999 Wiley-Liss, Inc." @default.
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• W2143005000 date "1999-07-01" @default.
• W2143005000 modified "2023-10-14" @default.
• W2143005000 title "Amniotic fluid glucose and cytokines values in the early diagnosis of amniotic infection in patients with preterm labor and intact membranes" @default.
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• W2143005000 doi "https://doi.org/10.1002/(sici)1520-6661(199907/08)8:4<155::aid-mfm3>3.0.co;2-2" @default.
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