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- W2143018668 abstract "In this paper we have studied three aspects of the biological effectiveness of the cyclotron neutrons as compared with X irradiations: firstly, oxygen enhancement ratios for fast neutrons and for X rays were compared using survival of Ehrlich ascites tumour cells as a basis for judging the likelihood of improvements in the treatment of partially anoxic tumours; secondly, RBEs for different types of damage in different tissues and organs were measured in order to see whether these fell into a narrow range, which could be considered to be typical of the neutron beam, or whether the values differed for different biological end points; thirdly, some data were derived on the effects of fractionation. Four biological systems were used as follows. (1) Mouse Ehrlich ascites tumour cells, from which survival curves have been obtained after irradiation of the tumour in vitro under carefully controlled gas conditions. (2) Growth studies after irradiation of the Ehrlich ascites tumour grown as a solid tumour and irradiated in vivo. (3) Weight loss in mouse testis following irradiation has been measured at 28 days and at the time of maximum loss. (4) The survival of chick embryos irradiated after four days incubation as measured at 24 hours and six days after irradiation." @default.
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- W2143018668 date "1963-02-01" @default.
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- W2143018668 title "IV. Comparisons of the Effects of X Rays and Cyclotron Neutrons on Mouse Ascites Tumours, Mouse Testis and Chick Embryos" @default.
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- W2143018668 doi "https://doi.org/10.1259/0007-1285-36-422-92" @default.
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