FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143045019> ?p ?o ?g. }

• W2143045019 endingPage "945" @default.
• W2143045019 startingPage "937" @default.
• W2143045019 abstract "Objective The aim of this study was to evaluate the prognostic value of E-cadherin, β-catenin, vimentin and S100A4 expression in a cohort of squamous cell lung carcinoma (SqCC) patients. Methods Tumours from 204 patients with surgically resected SqCC were used for the immunohistochemical analyses of E-cadherin, β-catenin, vimentin and S100A4 expression. Correlations between the expression of these markers and clinicopathological parameters were analysed using the χ 2 test. The prognostic value of these markers was evaluated using univariate Kaplan–Meier survival analyses and multivariate Cox proportional hazards model analyses. Results Significant associations between E-cadherin expression and T stage (p=0.040), histological differentiation (p=0.005), lymph node metastasis (p<0.001), and recurrence (p<0.001) were identified. Decreased β-catenin expression was significantly correlated with T stage (p=0.003) and lymph node metastasis (p=0.010). Vimentin expression was associated with histological differentiation (p=0.017) and lymph node metastasis (p=0.001). Moreover, significant correlations were observed between S100A4 expression and lymph node metastasis (p=0.020) and recurrence (p<0.001). In the univariate analyses, high E-cadherin expression was a positive indicator for overall survival (OS) (p<0.001) and disease-free survival (DFS) (p<0.001), whereas high S100A4 or vimentin expression were negative indicators for OS (p<0.001 and p=0.010, respectively) and DFS (p<0.001 and p=0.006, respectively). In the multivariate analyses, E-cadherin and S100A4 expression were independent prognostic factors for OS (HR 0.697, 95% CI 0.524 to 0.926, p=0.013, and HR 1.508, 95% CI 1.122 to 2.027, p=0.007, respectively) and DFS (HR 0.634, 95% CI 0.471 to 0.852, p=0.003, and HR 1.490, 95% CI 1.101 to 2.015, p=0.010, respectively). Conclusions Effective analysis of E-cadherin and S100A4 expression may allow for the identification of patients who are at a high risk of recurrence and poor prognosis in SqCC." @default.
• W2143045019 created "2016-06-24" @default.
• W2143045019 creator A5027835055 @default.
• W2143045019 creator A5032529955 @default.
• W2143045019 creator A5061476822 @default.
• W2143045019 creator A5062337174 @default.
• W2143045019 creator A5068832650 @default.
• W2143045019 creator A5070019758 @default.
• W2143045019 creator A5081342373 @default.
• W2143045019 date "2013-07-13" @default.
• W2143045019 modified "2023-10-01" @default.
• W2143045019 title "Clinical significance of E-cadherin, β-catenin, vimentin and S100A4 expression in completely resected squamous cell lung carcinoma" @default.
• W2143045019 cites W109896574 @default.
• W2143045019 cites W1980507112 @default.
• W2143045019 cites W1983991097 @default.
• W2143045019 cites W1984093042 @default.
• W2143045019 cites W1996118868 @default.
• W2143045019 cites W1997763924 @default.
• W2143045019 cites W2011630672 @default.
• W2143045019 cites W2014691022 @default.
• W2143045019 cites W2014773666 @default.
• W2143045019 cites W2015418522 @default.
• W2143045019 cites W2018628280 @default.
• W2143045019 cites W2020703068 @default.
• W2143045019 cites W2027640690 @default.
• W2143045019 cites W2032931851 @default.
• W2143045019 cites W2038088306 @default.
• W2143045019 cites W2042240216 @default.
• W2143045019 cites W2043103956 @default.
• W2143045019 cites W2044261750 @default.
• W2143045019 cites W2046629102 @default.
• W2143045019 cites W2048067731 @default.
• W2143045019 cites W2048674016 @default.
• W2143045019 cites W2055130200 @default.
• W2143045019 cites W2059918221 @default.
• W2143045019 cites W2062186508 @default.
• W2143045019 cites W2085781596 @default.
• W2143045019 cites W2086050575 @default.
• W2143045019 cites W2102059693 @default.
• W2143045019 cites W2112659392 @default.
• W2143045019 cites W2120318554 @default.
• W2143045019 cites W2135789296 @default.
• W2143045019 cites W2142819263 @default.
• W2143045019 cites W2144660856 @default.
• W2143045019 cites W2148650874 @default.
• W2143045019 cites W2153397369 @default.
• W2143045019 cites W2157586477 @default.
• W2143045019 cites W2158687576 @default.
• W2143045019 cites W2182884407 @default.
• W2143045019 cites W2334141130 @default.
• W2143045019 cites W4239180165 @default.
• W2143045019 doi "https://doi.org/10.1136/jclinpath-2013-201467" @default.
• W2143045019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23853314" @default.
• W2143045019 hasPublicationYear "2013" @default.
• W2143045019 type Work @default.
• W2143045019 sameAs 2143045019 @default.
• W2143045019 citedByCount "52" @default.
• W2143045019 countsByYear W21430450192014 @default.
• W2143045019 countsByYear W21430450192015 @default.
• W2143045019 countsByYear W21430450192016 @default.
• W2143045019 countsByYear W21430450192017 @default.
• W2143045019 countsByYear W21430450192018 @default.
• W2143045019 countsByYear W21430450192019 @default.
• W2143045019 countsByYear W21430450192020 @default.
• W2143045019 countsByYear W21430450192021 @default.
• W2143045019 countsByYear W21430450192022 @default.
• W2143045019 countsByYear W21430450192023 @default.
• W2143045019 crossrefType "journal-article" @default.
• W2143045019 hasAuthorship W2143045019A5027835055 @default.
• W2143045019 hasAuthorship W2143045019A5032529955 @default.
• W2143045019 hasAuthorship W2143045019A5061476822 @default.
• W2143045019 hasAuthorship W2143045019A5062337174 @default.
• W2143045019 hasAuthorship W2143045019A5068832650 @default.
• W2143045019 hasAuthorship W2143045019A5070019758 @default.
• W2143045019 hasAuthorship W2143045019A5081342373 @default.
• W2143045019 hasConcept C121608353 @default.
• W2143045019 hasConcept C126322002 @default.
• W2143045019 hasConcept C142724271 @default.
• W2143045019 hasConcept C143998085 @default.
• W2143045019 hasConcept C144301174 @default.
• W2143045019 hasConcept C146357865 @default.
• W2143045019 hasConcept C147447768 @default.
• W2143045019 hasConcept C1491633281 @default.
• W2143045019 hasConcept C149402561 @default.
• W2143045019 hasConcept C151730666 @default.
• W2143045019 hasConcept C204232928 @default.
• W2143045019 hasConcept C2777546739 @default.
• W2143045019 hasConcept C2779013556 @default.
• W2143045019 hasConcept C2780849966 @default.
• W2143045019 hasConcept C38180746 @default.
• W2143045019 hasConcept C50382708 @default.
• W2143045019 hasConcept C54355233 @default.
• W2143045019 hasConcept C71924100 @default.
• W2143045019 hasConcept C86803240 @default.
• W2143045019 hasConceptScore W2143045019C121608353 @default.
• W2143045019 hasConceptScore W2143045019C126322002 @default.
• W2143045019 hasConceptScore W2143045019C142724271 @default.
• W2143045019 hasConceptScore W2143045019C143998085 @default.

• next