FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2143048304> ?p ?o ?g. }

• W2143048304 endingPage "843" @default.
• W2143048304 startingPage "838" @default.
• W2143048304 abstract "OBJECTIVE Corneal confocal microscopy is a novel diagnostic technique for the detection of nerve damage and repair in a range of peripheral neuropathies, in particular diabetic neuropathy. Normative reference values are required to enable clinical translation and wider use of this technique. We have therefore undertaken a multicenter collaboration to provide worldwide age-adjusted normative values of corneal nerve fiber parameters. RESEARCH DESIGN AND METHODS A total of 1,965 corneal nerve images from 343 healthy volunteers were pooled from six clinical academic centers. All subjects underwent examination with the Heidelberg Retina Tomograph corneal confocal microscope. Images of the central corneal subbasal nerve plexus were acquired by each center using a standard protocol and analyzed by three trained examiners using manual tracing and semiautomated software (CCMetrics). Age trends were established using simple linear regression, and normative corneal nerve fiber density (CNFD), corneal nerve fiber branch density (CNBD), corneal nerve fiber length (CNFL), and corneal nerve fiber tortuosity (CNFT) reference values were calculated using quantile regression analysis. RESULTS There was a significant linear age-dependent decrease in CNFD (−0.164 no./mm2 per year for men, P &lt; 0.01, and −0.161 no./mm2 per year for women, P &lt; 0.01). There was no change with age in CNBD (0.192 no./mm2 per year for men, P = 0.26, and −0.050 no./mm2 per year for women, P = 0.78). CNFL decreased in men (−0.045 mm/mm2 per year, P = 0.07) and women (−0.060 mm/mm2 per year, P = 0.02). CNFT increased with age in men (0.044 per year, P &lt; 0.01) and women (0.046 per year, P &lt; 0.01). Height, weight, and BMI did not influence the 5th percentile normative values for any corneal nerve parameter. CONCLUSIONS This study provides robust worldwide normative reference values for corneal nerve parameters to be used in research and clinical practice in the study of diabetic and other peripheral neuropathies." @default.
• W2143048304 created "2016-06-24" @default.
• W2143048304 creator A5000841344 @default.
• W2143048304 creator A5026945028 @default.
• W2143048304 creator A5030498027 @default.
• W2143048304 creator A5031158173 @default.
• W2143048304 creator A5033575514 @default.
• W2143048304 creator A5035371538 @default.
• W2143048304 creator A5043566990 @default.
• W2143048304 creator A5047457945 @default.
• W2143048304 creator A5049406112 @default.
• W2143048304 creator A5049705278 @default.
• W2143048304 creator A5050036233 @default.
• W2143048304 creator A5071820799 @default.
• W2143048304 creator A5072691306 @default.
• W2143048304 creator A5077171863 @default.
• W2143048304 creator A5082026989 @default.
• W2143048304 creator A5082983207 @default.
• W2143048304 creator A5091487204 @default.
• W2143048304 date "2015-01-29" @default.
• W2143048304 modified "2023-10-11" @default.
• W2143048304 title "Normative Values for Corneal Nerve Morphology Assessed Using Corneal Confocal Microscopy: A Multinational Normative Data Set" @default.
• W2143048304 cites W1504350555 @default.
• W2143048304 cites W1854315659 @default.
• W2143048304 cites W1916590412 @default.
• W2143048304 cites W1972723379 @default.
• W2143048304 cites W2009359450 @default.
• W2143048304 cites W2027326244 @default.
• W2143048304 cites W2036196846 @default.
• W2143048304 cites W2036255272 @default.
• W2143048304 cites W2042805349 @default.
• W2143048304 cites W2046632943 @default.
• W2143048304 cites W2052861422 @default.
• W2143048304 cites W2060761781 @default.
• W2143048304 cites W2068279167 @default.
• W2143048304 cites W2069015893 @default.
• W2143048304 cites W2094239852 @default.
• W2143048304 cites W2096121163 @default.
• W2143048304 cites W2101631478 @default.
• W2143048304 cites W2103243775 @default.
• W2143048304 cites W2108663538 @default.
• W2143048304 cites W2113599279 @default.
• W2143048304 cites W2117172569 @default.
• W2143048304 cites W2123715778 @default.
• W2143048304 cites W2126539362 @default.
• W2143048304 cites W2136253074 @default.
• W2143048304 cites W2137020103 @default.
• W2143048304 cites W2139960926 @default.
• W2143048304 cites W2147926338 @default.
• W2143048304 cites W2150666931 @default.
• W2143048304 cites W2154145465 @default.
• W2143048304 cites W2156165690 @default.
• W2143048304 doi "https://doi.org/10.2337/dc14-2311" @default.
• W2143048304 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4407754" @default.
• W2143048304 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25633665" @default.
• W2143048304 hasPublicationYear "2015" @default.
• W2143048304 type Work @default.
• W2143048304 sameAs 2143048304 @default.
• W2143048304 citedByCount "142" @default.
• W2143048304 countsByYear W21430483042015 @default.
• W2143048304 countsByYear W21430483042016 @default.
• W2143048304 countsByYear W21430483042017 @default.
• W2143048304 countsByYear W21430483042018 @default.
• W2143048304 countsByYear W21430483042019 @default.
• W2143048304 countsByYear W21430483042020 @default.
• W2143048304 countsByYear W21430483042021 @default.
• W2143048304 countsByYear W21430483042022 @default.
• W2143048304 countsByYear W21430483042023 @default.
• W2143048304 crossrefType "journal-article" @default.
• W2143048304 hasAuthorship W2143048304A5000841344 @default.
• W2143048304 hasAuthorship W2143048304A5026945028 @default.
• W2143048304 hasAuthorship W2143048304A5030498027 @default.
• W2143048304 hasAuthorship W2143048304A5031158173 @default.
• W2143048304 hasAuthorship W2143048304A5033575514 @default.
• W2143048304 hasAuthorship W2143048304A5035371538 @default.
• W2143048304 hasAuthorship W2143048304A5043566990 @default.
• W2143048304 hasAuthorship W2143048304A5047457945 @default.
• W2143048304 hasAuthorship W2143048304A5049406112 @default.
• W2143048304 hasAuthorship W2143048304A5049705278 @default.
• W2143048304 hasAuthorship W2143048304A5050036233 @default.
• W2143048304 hasAuthorship W2143048304A5071820799 @default.
• W2143048304 hasAuthorship W2143048304A5072691306 @default.
• W2143048304 hasAuthorship W2143048304A5077171863 @default.
• W2143048304 hasAuthorship W2143048304A5082026989 @default.
• W2143048304 hasAuthorship W2143048304A5082983207 @default.
• W2143048304 hasAuthorship W2143048304A5091487204 @default.
• W2143048304 hasBestOaLocation W21430483041 @default.
• W2143048304 hasConcept C105702510 @default.
• W2143048304 hasConcept C118487528 @default.
• W2143048304 hasConcept C2776823239 @default.
• W2143048304 hasConcept C2776882836 @default.
• W2143048304 hasConcept C2777723521 @default.
• W2143048304 hasConcept C2779178360 @default.
• W2143048304 hasConcept C71924100 @default.
• W2143048304 hasConcept C86803240 @default.
• W2143048304 hasConcept C95444343 @default.
• W2143048304 hasConceptScore W2143048304C105702510 @default.
• W2143048304 hasConceptScore W2143048304C118487528 @default.

• next