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- W2143072009 abstract "An efficient stereoselective total synthesis of (+)-mupirocin H is described. The chiron and asymmetric strategies were appropriately utilized for the rapid construction of the novel five-membered lactone with six stereogenic centres. The C3–C5 triol segment was derived directly from readily-available D-ribose, and the chirality at the C6 position was introduced by means of substrate-controlled conjugate addition. The remaining chiral centers (C10 and C11) were obtained by Oppolzer's protocol, and the olefin was generated through a Julia–Kocienski olefination." @default.
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- W2143072009 date "2014-07-29" @default.
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- W2143072009 title "An expedient total synthesis of mupirocin H" @default.
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- W2143072009 doi "https://doi.org/10.1039/c4ra06373b" @default.
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