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• W2143128764 endingPage "4859" @default.
• W2143128764 startingPage "4853" @default.
• W2143128764 abstract "ABSTRACT In this paper, we report on the potential use of atomic force microscopy (AFM) as a tool to measure the intermolecular forces in biofilm structures and to study the effect of silver ions on sessile Staphylococcus epidermidis cell viability and stability. We propose a strategy of destabilizing the biofilm matrix by reducing the intermolecular forces within the extracellular polymeric substances (EPSs) using a low concentration (50 ppb) of silver ions. Our AFM studies on the intermolecular forces within the EPSs of S. epidermidis RP62A and S . epidermidis 1457 biofilms suggest that the silver ions can destabilize the biofilm matrix by binding to electron donor groups of the biological molecules. This leads to reductions in the number of binding sites for hydrogen bonds and electrostatic and hydrophobic interactions and, hence, the destabilization of the biofilm structure." @default.
• W2143128764 created "2016-06-24" @default.
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• W2143128764 creator A5011744252 @default.
• W2143128764 creator A5056917996 @default.
• W2143128764 date "2005-12-01" @default.
• W2143128764 modified "2023-10-01" @default.
• W2143128764 title "Role of Silver Ions in Destabilization of Intermolecular Adhesion Forces Measured by Atomic Force Microscopy in <i>Staphylococcus epidermidis</i> Biofilms" @default.
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• W2143128764 doi "https://doi.org/10.1128/aac.49.12.4853-4859.2005" @default.
• W2143128764 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1315927" @default.
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